Patents by Inventor Junmiao LI

Junmiao LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FURAN FUSED RING-SUBSTITUTED GLUTARIMIDE COMPOUND
    Publication number: 20240190851
    Abstract: Disclosed are a series of furan fused ring-substituted glutarimide compounds and an application thereof in preparation of a drug for treating related diseases. In particular, disclosed is a compound represented by formula (II) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 16, 2022
    Publication date: June 13, 2024
    Inventors: Maoyi LEI, Junmiao LI, Shuhui CHEN
  • Bicyclic compound that acts as CRBN protein regulator
    Patent number: 11905276
    Abstract: A compound represented by formula (III) or a pharmaceutically acceptable salt thereof, and disclosed is an application thereof in the preparation of a medication for treating diseases related to a CRBN receptor.
    Type: Grant
    Filed: September 14, 2020
    Date of Patent: February 20, 2024
    Assignee: MEDSHINE DISCOVERY INC.
    Inventors: Yunfu Luo, Maoyi Lei, Yu Xu, Junmiao Li, Guoli Zhang, Jinghong Dong, Shuhui Chen
  • BICYCLIC COMPOUND THAT ACTS AS CRBN PROTEIN REGULATOR
    Publication number: 20230348441
    Abstract: A compound represented by formula (III) or a pharmaceutically acceptable salt thereof, and disclosed is an application thereof in the preparation of a medication for treating diseases related to a CRBN receptor.
    Type: Application
    Filed: September 14, 2020
    Publication date: November 2, 2023
    Inventors: Yunfu LUO, Maoyi LEI, Yu XU, Junmiao LI, Guoli ZHANG, Jinghong DONG, Shuhui CHEN
  • PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME
    Publication number: 20230158152
    Abstract: A proteolysis targeting chimera (PROTAC), and an application thereof in preparation of a drug for treating a related disease. Specifically disclosed are a compound as represented by formula (I) and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 17, 2021
    Publication date: May 25, 2023
    Inventors: Maoyi LEI, Lei PENG, Yunfu LUO, Yu XU, Junmiao LI, Xinyuan DENG, Zisheng KANG, Weizhi GE, GuoIi ZHANG, Shuhui CHEN
  • Medical application of pyrimidine sulfonamides derivatives
    Patent number: 11628168
    Abstract: The present disclosure provides application of a compound in conformity with a general formula I and an isomer or pharmaceutically acceptable salt thereof to preparation of a medicinal composition for treating or preventing a high altitude disease. The high altitude disease is selected from an acute high altitude disease and a chronic high altitude disease generated in a high altitude environment with an altitude of 2,000 m or above.
    Type: Grant
    Filed: June 5, 2019
    Date of Patent: April 18, 2023
    Assignees: CHINESE PLA GENERAL HOSPITAL, SHIJIAZHUANG SAGACITY NEW DRUG DEVELOPMENT COMPANY, LTD.
    Inventors: Kunlun He, Xiaojian Gao, Chunlei Liu, Zeyu Zhang, Xin Li, Chen Li, Yunfu Luo, Maoyi Lei, Junmiao Li, Yiwei Wang
  • CRYSTAL FORM OF PYRIMIDINE SULFONAMIDE COMPOUND AND PREPARATION METHOD THEREFOR
    Publication number: 20220220098
    Abstract: Disclosed are a Crystal Form (I) of a pyrimidine sulfonamide compound and a preparation method therefor. The present disclosure relates to an application thereof in the preparation of a medicament for treating diseases related to ETA receptor antagonists.
    Type: Application
    Filed: May 22, 2020
    Publication date: July 14, 2022
    Inventors: Junmiao LI, Maoyi LEI, Yunfu LUO
  • Pyrimidine sulfamide derivative and preparation method and medical application thereof
    Patent number: 11319305
    Abstract: Disclosed are a series of pyrimidine sulfamide compounds and applications thereof in preparing a drug for a disease related to an ETA receptor antagonist. In particular, disclosed is a derived compound represented by formula (I) or a tautomer or pharmaceutically acceptable composition thereof.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: May 3, 2022
    Assignee: Shijiazhuang Sagacity New Drug Development Co., Ltd.
    Inventors: Yunfu Luo, Maoyi Lei, Junmiao Li, Yu Xu, Ran Wei, Shuhui Chen
  • MEDICAL APPLICATION OF PYRIMIDINE SULFONAMIDES DERIVATIVES
    Publication number: 20210393627
    Abstract: The present disclosure provides application of a compound in conformity with a general formula I and an isomer or pharmaceutically acceptable salt thereof to preparation of a medicinal composition for treating or preventing a high altitude disease. The high altitude disease is selected from an acute high altitude disease and a chronic high altitude disease generated in a high altitude environment with an altitude of 2,000 m or above.
    Type: Application
    Filed: June 5, 2019
    Publication date: December 23, 2021
    Applicants: CHINESE PLA GENERAL HOSPITAL, SHIJIAZHUANG SAGACITY NEW DRUG DEVELOPMENT COMPANY, LTD.
    Inventors: Kunlun HE, Xiaojian GAO, Chunlei LIU, Zeyu ZHANG, Xin LI, Chen LI, Yunfu LUO, Maoyi LEI, Junmiao LI, Yiwei WANG
  • PYRIMIDINE SULFAMIDE DERIVATIVE AND PREPARATION METHOD AND MEDICAL APPLICATION THEREOF
    Publication number: 20200283425
    Abstract: Disclosed are a series of pyrimidine sulfamide compounds and applications thereof in preparing a drug for a disease related to an ETA receptor antagonist. In particular, disclosed is a derived compound represented by formula (I) or a tautomer or pharmaceutically acceptable composition thereof.
    Type: Application
    Filed: November 19, 2018
    Publication date: September 10, 2020
    Inventors: Yunfu LUO, Maoyi LEI, Junmiao LI, Yu XU, Ran WEI, Shuhui CHEN