Patents by Inventor Junping PAN

Junping PAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of Crassifolin A in preparation of drug for promoting mitophagy and treating neurodegenerative diseases
    Patent number: 12691094
    Abstract: Disclosed in the present invention is the use of Crassifolin A in promoting mitophagy and treating neurodegenerative diseases. According to the present invention, experiments show that the diterpene compound Crassifolin A can significantly increase mitophagy levels, promote the removal of damaged mitochondria, maintain homeostasis in cells, and has potential effects of treating neurodegenerative diseases and other related diseases; moreover, Crassifolin A is a small-molecule compound that can easily penetrate through the blood-brain barrier to reach the brain so as to play a role, can be extracted from a Thickleaf croton root medicinal material, has the advantages of abundant medicinal sources, easy availability, low drug toxicity and few side effects, and has a good application prospect in the treatment of neurodegenerative diseases.
    Type: Grant
    Filed: June 22, 2022
    Date of Patent: July 28, 2026
    Assignee: JINAN UNIVERSITY
    Inventors: Yubo Zhang, Fei Xiao, Guocai Wang, Evandro Fei Fang, Junping Pan
  • USE OF CRASSIFOLIN A IN PREPARATION OF DRUG FOR PROMOTING MITOPHAGY AND TREATING NEURODEGENERATIVE DISEASES
    Publication number: 20240299342
    Abstract: Disclosed in the present invention is the use of Crassifolin A in promoting mitophagy and treating neurodegenerative diseases. According to the present invention, experiments show that the diterpene compound Crassifolin A can significantly increase mitophagy levels, promote the removal of damaged mitochondria, maintain homeostasis in cells, and has potential effects of treating neurodegenerative diseases and other related diseases; moreover, Crassifolin A is a small-molecule compound that can easily penetrate through the blood-brain barrier to reach the brain so as to play a role, can be extracted from a Thickleaf croton root medicinal material, has the advantages of abundant medicinal sources, easy availability, low drug toxicity and few side effects, and has a good application prospect in the treatment of neurodegenerative diseases.
    Type: Application
    Filed: June 22, 2022
    Publication date: September 12, 2024
    Applicant: JINAN UNIVERSITY
    Inventors: Yubo ZHANG, Fei XIAO, Guocai WANG, Evandro Fei FANG, Junping PAN