Patents by Inventor Junwen MA

Junwen MA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of human milk oligosaccharides by a beta-N-acetylhexosaminidase from sp
    Patent number: 12577599
    Abstract: The invention discloses the application of a ?-N-acetylhexosaminidase (HaHex74) from Haloferula sp. in the synthesis of human milk oligosaccharides. The invention provides the use of HaHex74 protein or related biological materials thereof in any one of the following: synthesizing human milk oligosaccharides; synthesizing Lacto-N-triose II and/or Lacto-N-neotetraose; the HaHex74 protein having the amino acid sequence shown in SEQ ID No. 2 is derived from Haloferula sp. The ?-N-acetylhexosaminidase HaHex74 disclosed by the invention possesses high-level expression, excellent hydrolysis properties and transglycosylation activity, which may make it potentially useful in the production of human milk oligosaccharides.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: March 17, 2026
    Assignee: CHINA AGRICULTURAL UNIVERSITY
    Inventors: Zhengqiang Jiang, Yihao Liu, Shaoqing Yang, Junwen Ma, Qiaojuan Yan, Ting Li
  • Synthesis of human milk oligosaccharides by a Beta-N-acetylhexosaminidase from Haloferula sp.
    Publication number: 20230011163
    Abstract: The invention discloses the application of a ?-N-acetylhexosaminidase (HaHex74) from Haloferula sp. in the synthesis of human milk oligosaccharides. The invention provides the use of HaHex74 protein or related biological materials thereof in any one of the following: synthesizing human milk oligosaccharides; synthesizing Lacto-N-triose II and/or Lacto-N-neotetraose; the HaHex74 protein having the amino acid sequence shown in SEQ ID No. 2 is derived from Haloferula sp. The ?-N-acetylhexosaminidase HaHex74 disclosed by the invention possesses high-level expression, excellent hydrolysis properties and transglycosylation activity, which may make it potentially useful in the production of human milk oligosaccharides.
    Type: Application
    Filed: October 20, 2020
    Publication date: January 12, 2023
    Inventors: Zhengqiang JIANG, Yihao LIU, Shaoqing YANG, Junwen MA, Qiaojuan YAN, Ting LI