Abstract: A device for dispensing a liquid product, comprising: a container (2) including an opening to dispense the liquid product; an outer screw cap (3), which is configured to be mounted onto the container (2); an inner cap (4), which is engageable with the outer screw cap (3) and movable thereon from an open position in which the liquid product is dispensed from the container (2), to a closed position in which the liquid product is blocked from flowing out; and an applicator (5) coupled to the inner cap (4) and configured to dispense the liquid product therefrom; wherein a channel (321) is formed on a portion of the outer screw cap (3) for engaging with the inner cap (4), and a slider (413) is formed on the inner cap (4), and the slider (413) slides along the channel (321) during the rotation of the inner cap (4) with respect to the outer screw cap (3) between the open position and the closed position, and during the rotation towards the open position, the inner cap (4) will axially move away from the outer screw

Abstract: A panel structure for a hidden water tank includes: a panel mounting frame configured to be connected to a water tank body; a panel body disposed on an outer side of the panel mounting frame and configured to be opened and closed relative to the panel mounting frame; and a hinge configured to connect a first end of the panel body to the panel mounting frame. A second end of the panel body is connected to the panel mounting frame.

Abstract: Disclosed are a quick liquid injection structure and an aerosol generating device. The quick liquid injection structure includes a valve body, a liquid-injection tube and an elastic member. A gas exhaust hole is disposed on a side wall of the valve body. The liquid-injection tube is coaxially disposed within the valve body, and the liquid-injection tube comprises a liquid-inlet port, a liquid injection passageway and a liquid-outlet hole which are fluidly communicated. The elastic member is sleeved outside the liquid-injection tube, one end of the elastic member abuts against a first abutment part that extends from an outer wall of the liquid-injection tube, and another end of the elastic member abuts against a second abutment part that extends from an inner wall of the valve body. An exhaust gap is formed between the valve body and an end of the liquid-injection tube close to the liquid-inlet port.

Abstract: Disclosed are a quick liquid injection structure and an aerosol generating device. The quick liquid injection structure includes a valve body, a liquid-injection tube and an elastic member. A gas exhaust hole is disposed on a side wall of the valve body. The liquid-injection tube is coaxially disposed within the valve body, and the liquid-injection tube comprises a liquid-inlet port, a liquid injection passageway and a liquid-outlet hole which are fluidly communicated. The elastic member is sleeved outside the liquid-injection tube, one end of the elastic member abuts against a first abutment part that extends from an outer wall of the liquid-injection tube, and another end of the elastic member abuts against a second abutment part that extends from an inner wall of the valve body. An exhaust gap is formed between the valve body and an end of the liquid-injection tube close to the liquid-inlet port.

Abstract: Embodiments of the present disclosure relates to dynamic virtual platoon. According to embodiments of the present disclosure, a first device receives driving information from vehicles and forwards the driving information to a network device. The second device determines the vehicle platoon based on the driving information and transmits the information related to the vehicle platoon to the first device. The first device determines control information to remotely drive the vehicles. In this way, the coverage of the vehicle platoon is increased and a dynamic platoon is formed. The first device controls the driving of the vehicles instead of the head vehicle, which reduces burden on the head vehicle.

Abstract: The present invention provides a method for constructing a high-throughput sequencing library, which comprises: fragmenting genomic DNA; end-repairing the DNA fragments; adding a base A to the 3? end of the end-repaired DNA fragments; connecting the DNA fragments having cohesive end A with a methylated adapter; carrying out hybrid capture on the connection products by using specific probes to obtain object fragments; treating the object fragments with bisulfite, to convert non-methylated cytosines to uracils; PCR amplifying the converted object fragments; and separating and purifying the amplification products, wherein the amplification products constitute the high-throughput sequencing library. The present invention also provides a method and an apparatus for identifying methylation information in specified genome regions of a sample.

Abstract: A method for detecting hydroxymethylation modification in nucleic acid comprises: glycosylating the nucleic acid, digesting with MspI, ligating the digested fragments to a biotin-labeled linker at both ends thereof, digesting with NlaIII; capturing the digested fragments using streptavidin magnetic beads to produce fragments having the biotin-labeled linker at one end and a CATG 4-base sticky end at the other end, wherein these fragments reveal modification information of their adjacent CCGG sites; ligating the CATG sticky end to a linker containing a recognition site of MmeI or Ecop15I, digesting with corresponding restriction endonuclease to produce short sequence fragments that can reveal modification information of their adjacent CCGG sites; and performing a tag number comparison to obtain information about methylation and hydroxymethylation modification relative levels. A use of the method is also provided.

Abstract: Provided is a high throughput methylation detection method, particularly a combined sequence capture and bisulfite sequencing method. The method accurately and effectively analyzes the methylation status of the target area in several samples simultaneously, lowers the difficulty of probe design, enhances operation and application feasibility, and enables high throughput methylation detection of high accuracy on interested target sequences and areas in a complete genome. The method is targeted and conserves energy and time.

Abstract: A method for detecting hydroxymethylation modification in nucleic acid comprises: glycosylating the nucleic acid, digesting with MspI, ligating the digested fragments to a biotin-labeled linker at both ends thereof, digesting with NlaIII; capturing the digested fragments using streptavidin magnetic beads to produce fragments having the biotin-labeled linker at one end and a CATG 4-base sticky end at the other end, wherein these fragments reveal modification information of their adjacent CCGG sites; ligating the CATG sticky end to a linker containing a recognition site of MmeI or Ecop15I, digesting with corresponding restriction endonuclease to produce short sequence fragments that can reveal modification information of their adjacent CCGG sites; and performing a tag number comparison to obtain information about methylation and hydroxymethylation modification relative levels. A use of the method is also provided.

Abstract: The present invention provides a method for constructing a high-throughput sequencing library, which comprises: fragmenting genomic DNA; end-repairing the DNA fragments; adding a base A to the 3? end of the end-repaired DNA fragments; connecting the DNA fragments having cohesive end A with a methylated adapter; carrying out hybrid capture on the connection products by using specific probes to obtain object fragments; treating the object fragments with bisulfite, to convert non-methylated cytosines to uracils; PCR amplifying the converted object fragments; and separating and purifying the amplification products, wherein the amplification products constitute the high-throughput sequencing library. The present invention also provides a method and an apparatus for identifying methylation information in specified genome regions of a sample.

Abstract: Provided is a high throughput methylation detection method, particularly a combined sequence capture and bisulfite sequencing method. The method accurately and effectively analyzes the methylation status of the target area in several samples simultaneously, lowers the difficulty of probe design, enhances operation and application feasibility, and enables high throughput methylation detection of high accuracy on interested target sequences and areas in a complete genome. The method is targeted and conserves energy and time.