Abstract: Disclosed in the present invention is use of a long-acting ?2AR agonist or pharmaceutically acceptable salts thereof in preparation of drugs for treating cancer. The long-acting ?2AR agonist of the present invention can target ?2AR on the surface of a cancer cell membrane as a single functional molecular target, and perform targeted inhibition on a self-renewal capability of cancer stem cells to exert a function of inhibiting cancer initiation and progression. Therefore, the ?2AR agonist may be clinically used for treating cancer. In addition, as a repurposed drug, the long-acting ?2AR agonist may exhibit enhanced clinical translation potential and druggability.

Abstract: A lighting device, comprising a housing, a light emitting diode, an optical system configured to at least partially collimate light emissions in a forward direction; and a removable accessory that reflects a portion of the light emissions more than 90 degrees from the forward direction. Also, a lighting device comprising a housing and a plurality of light emitters arranged in a row, and a light distribution-modifying element comprising a body portion and a plurality of light distribution-modifying protrusions (each comprising a reflection surface) arranged in a row substantially parallel to the row of light emitters, at least some of the light emitters aligned with at least some of the plurality of light distribution-modifying protrusions as respective pairs. Also, a light distribution-modifying element, and a lighting device comprising a housing, at least one light emitter, and a light distribution-modifying element comprising a body portion and a light distribution-modifying protrusion. Also, methods.

Abstract: A lighting device, comprising a housing, a light emitting diode, an optical system configured to at least partially collimate light emissions in a forward direction; and a removable accessory that reflects a portion of the light emissions more than 90 degrees from the forward direction. Also, a lighting device comprising a housing and a plurality of light emitters arranged in a row, and a light distribution-modifying element comprising a body portion and a plurality of light distribution-modifying protrusions (each comprising a reflection surface) arranged in a row substantially parallel to the row of light emitters. at least some of the light emitters aligned with at least some of the plurality of light distribution-modifying protrusions as respective pairs. Also, a light distribution-modifying element, and a lighting device comprising a housing, at least one light emitter, and a light distribution-modifying element comprising a body portion and a light distribution-modifying protrusion. Also, methods.