Abstract: Disclosed are a drug-carrier complex and a preparation method therefor and use thereof. The drug-carrier complex comprises an active ingredient and a carrier, wherein the carrier is albumin, the active ingredient is loaded on the carrier, and the active ingredient is a platinum-based drug. Compared with free platinum-based drugs, the drug-carrier complex can significantly extend in vivo half-life of the platinum-based drug, improve in vivo tissue distribution of the platinum-based drug, increase tissue selectivity of the platinum-based drug, reduce damage to normal tissues and systemic toxicity of the platinum-based drug, and thus improve therapeutic effect.