Patents by Inventor Junxing Shi

Junxing Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N4-acylcytosine-1,3-dioxolane nucleosides for treatment of viral infections
    Patent number: 6908924
    Abstract: The present invention is directed to a compound, method and composition of treating or preventing viral infections, in particular, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts, comprising the administration of N4-acylcytosine-1,3-dioxolane and pharmaceutically acceptable salts, prodrugs, and other derivatives thereof.
    Type: Grant
    Filed: December 16, 2002
    Date of Patent: June 21, 2005
    Assignee: Pharmasset, Inc.
    Inventors: Kyoichi A. Watanabe, Junxing Shi, Michael J. Otto
  • BETA-2'-OR 3'-HALONUCLEOSIDES
    Publication number: 20050119286
    Abstract: The present invention includes compounds and compositions of ?-halonucleosides, as well as methods to treat HIV, HBV or abnormal cellular proliferation comprising administering said compounds or compositions.
    Type: Application
    Filed: June 24, 2002
    Publication date: June 2, 2005
    Inventors: Michael Otto, Junxing Shi, Chung Chu, Raymond Schinazi, Giuseppe Gumina, Youhoon Chong, Yongseok Choi
  • 2'-Fluoronucleosides
    Publication number: 20040254141
    Abstract: A class of 2′-fluoro-nucleoside compounds are disclosed which are useful in the treatment of hepatitis B infection, hepatitis C infection, HIV and abnormal cellular proliferation, including tumors and cancer.
    Type: Application
    Filed: March 8, 2004
    Publication date: December 16, 2004
    Inventors: Raymond F. Schinazi, Dennis C. Liotta, Chung K. Chu, J. Jeffrey McAtee, Junxing Shi, Yongseok Choi, Kyeong Lee, Joon H. Hong
  • N4-acylcytosine nucleosides for treatment of viral infections
    Publication number: 20040214844
    Abstract: The present invention is directed to a method and composition of treating or preventing viral infections, in particular, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts, comprising the administration of N4-acyl-2′,3′-dideoxy-5-fluorocytidine or N4-acyl-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine, and pharmaceutically acceptable salts, prodrugs, and other derivatives thereof.
    Type: Application
    Filed: December 13, 2002
    Publication date: October 28, 2004
    Inventors: Michael J. Otto, Junxing Shi, Kyoichi A. Watanabe
  • 2', 3'-Dideoxynucleoside analogues for the treatment or prevention of Flaviviridae infections
    Publication number: 20040067877
    Abstract: A method for the treatment or prevention of Flaviviridae infections, in particular, hepatitis C virus infection, in a host, and in particular, a human, is provided that includes administering an effective amount of a &bgr;-L- or &bgr;-D-2′,3′-dideoxynucleoside or a pharmaceutically acceptable salt or prodrug thereof, optionally in a pharmaceutically acceptable diluent or excipient.
    Type: Application
    Filed: August 1, 2003
    Publication date: April 8, 2004
    Inventors: Raymond F. Schinazi, Robert Striker, Junxing Shi
  • Modified fluorinated nucleoside analogues
    Publication number: 20040002476
    Abstract: The invention is a compound, composition, use for and a method of treating Flaviviridae (Hepacivirus, Flavirius, Pestivirus) infections, including BVDV and HCV, or abnormal cellular proliferation, including malignant tumors, in a host including animals, and especially humans, using a &bgr;-D or &bgr;-L nucleoside of general formula (I)-(XX), or their pharmaceutically acceptable salt or prodrug thereof.
    Type: Application
    Filed: February 13, 2003
    Publication date: January 1, 2004
    Inventors: Lieven J. Stuyver, Junxing Shi, Kyoichi A. Watanabe
  • N4-acylcytosine-1,3- dioxolane nucleosides for treatment of viral infections
    Publication number: 20030176319
    Abstract: The present invention is directed to a compound, method and composition of treating or preventing viral infections, in particular, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts, comprising the administration of N4-acylcytosine-1,3-dioxolane and pharmaceutically acceptable salts, prodrugs, and other derivatives thereof.
    Type: Application
    Filed: December 16, 2002
    Publication date: September 18, 2003
    Inventors: Kyoichi A. Watanabe, Junxing Shi, Michael J. Otto
  • Treatment of EBV and KHSV infection and associated abnormal cellular proliferation
    Publication number: 20030176392
    Abstract: A method and composition for the treatment, prevention and/or prophylaxis of a host, and in particular, a human, infected with Epstein-Barr virus (EBV), is provided that includes administering an effective amount of a 5-substituted uracil nucleoside or its pharmaceutically acceptable salt or prodrug, optionally in a pharmaceutically acceptable diluent or excipient.
    Type: Application
    Filed: December 19, 2002
    Publication date: September 18, 2003
    Inventors: Raymond F. Schinazi, Junxing Shi, Joyce D. Fingeroth, Erik Gustafson
  • 2'-fluoronucleosides
    Publication number: 20020198171
    Abstract: A class of 2′-fluoro-nucleoside compounds are disclosed which are useful in the treatment of hepatitis B infection, hepatitis C infection, HIV and abnormal cellular proliferation, including tumors and cancer.
    Type: Application
    Filed: January 30, 2002
    Publication date: December 26, 2002
    Inventors: Raymond F. Schinazi, Dennis C. Liotta, Chung K. Chu, J. Jeffrey McAtee, Junxing Shi, Yongseok Choi, Kyeong Lee, Joon H. Hong
  • 2?-Fluoronucleosides
    Patent number: 6348587
    Abstract: A class of 2′-fluoro-nucleoside compounds are disclosed which are useful in the treatment of hepatitis B infection, hepatitis C infection, HIV and abnormal cellular proliferation, including tumors and cancer.
    Type: Grant
    Filed: February 25, 1999
    Date of Patent: February 19, 2002
    Assignees: Emory University, University of Georgia Research Foundation, Inc.
    Inventors: Raymond F. Schinazi, Dennis C. Liotta, Chung K. Chu, J. Jeffrey McAtee, Junxing Shi, Yongseok Choi, Kyeong Lee, Joon H. Hong