Abstract: The present disclosure relates to an in vivo duct repair device and an operating method thereof. The in vivo duct repair device includes a catheter; a nozzle assembly, two axial ends thereof including a supplying end and a spraying end, respectively, the nozzle assembly having a first material flow channel arranged inside the nozzle assembly, a first material spout communicated with the first material flow channel and spraying a first material radially outwards, a second material flow channel arranged inside the nozzle assembly and isolated from the first material flow channel and a second material spout communicated with the second material flow channel and spraying a second material radially outwards, and the nozzle assembly being configured to enter the catheter and extend the spraying end out of an introducing end of the catheter; and a drive device connected to the supplying end.

Abstract: The present disclosure provides a bioprinter nozzle, a bioprinter and a lumen tissue construct printing method. The bioprinter nozzle includes: a bio-ink flow channel disposed inside the bioprinter nozzle; a bio-ink ejection port in communication with the bio-ink flow channel and located on the lateral side of an ejection end of the bioprinter nozzle; a medical adhesive flow channel disposed inside the bioprinter nozzle and isolated from the bio-ink flow channel; and a medical adhesive ejection port in communication with the medical adhesive flow channel and disposed on the lateral side of the ejection end, the medical adhesive ejection port and the bio-ink ejection port being arranged in a staggered manner in the axial direction of the bioprinter nozzle. The bioprinter includes the bioprinter nozzle. The lumen tissue construct printing method uses the bioprinter for printing.

Abstract: The present disclosure relates to a device for printing a lumen tissue construct, a method for using the same, and a 3D bioprinter. The device includes a spray head assembly for printing a biological construct; and a bioprinting platform for supporting a lumen tissue, and for carrying a biological construct printed by the spray head assembly, and for applying the biological construct to an inner surface of the lumen tissue. The device for printing a lumen tissue construct of the present disclosure provides the spray head assembly and the bioprinting platform, and the spray head assembly applies the biological construct onto the inner surface of the lumen tissue by the bioprinting platform, to avoid such problems as recurrence of thrombus and restenosis of a lumen after the lumen tissue has been implanted for a long time, thereby improving the biological reliability of the lumen tissue.

Abstract: The present disclosure relates to a manufacturing method of a lumen tissue construct. The manufacturing method of a lumen tissue construct comprises: step 1: installing elastic film on a support in a sleeving manner; step 3: printing a biological construct on the elastic film; step 5: forming a construct bonding layer on the biological construct; and step 7: bonding a lumen tissue to the construct bonding layer. In the manufacturing method of the lumen tissue construct of the present disclosure, the printed biological construct is assembled on the inner surface of the lumen tissue to form the lumen tissue construct, thereby helping to avoid occurrence of problems such as recurrence of thrombus, restenosis of lumen and the like after the lumen tissue construct is implanted for a long time, and improving the biological reliability of the lumen tissue construct.

Abstract: A device and method for printing lumen tissue constructs and a 3D bioprinter are disclosed. The device has a spray sprayhead assembly and a bioprinting platform. The spray sprayhead assembly prints a biological construct on an inner surface of a lumen tissue by the bioprinting platform. Problems, such as, recurrence of thrombus and restenosis of a lumen after the lumen tissue has been transplanted for a long time, can be avoided. The biological reliability of the lumen tissue can be improved.

Abstract: A device and method for printing lumen tissue constructs and a 3D bioprinter are disclosed. The device has a spray sprayhead assembly and a bioprinting platform. The spray sprayhead assembly prints a biological construct on an inner surface of a lumen tissue by the bioprinting platform. Problems, such as, recurrence of thrombus and restenosis of a lumen after the lumen tissue has been transplanted for a long time, can be avoided. The biological reliability of the lumen tissue can be improved.

Abstract: The present invention relates to a device for printing lumen tissue construct, a method for using the same and a 3D bioprinter. Wherein, the device comprises a spray sprayhead assembly and a bioprinting platform, the spray sprayhead assembly prints a biological construct on an inner surface of a lumen tissue by the bioprinting platform. the device for printing lumen tissue construct of the present invention provides the sprayhead assembly and the bioprinting platform, and the sprayhead assembly prints the biological construct on the inner surface of the lumen tissue by the bioprinting platform, thus avoid such problems as recurrence of thrombus and restenosis of a lumen after the lumen tissue has been transplanted for a long time, thereby improving the biological reliability of the lumen tissue.

Abstract: The present disclosure relates to a device for printing lumen tissue construct, a method for using the same and 3D bioprinter. Wherein, the device includes a spray head assembly for printing a biological construct; and a bioprinting platform for supporting a lumen tissue, and for carrying a biological construct printed by the spray head assembly, and for applying the biological construct to an inner surface of the lumen tissue. The device for printing lumen tissue construct of the present disclosure provides the spray head assembly and the bioprinting platform, and the spray head assembly applies the biological construct onto the inner surface of the lumen tissue by the bioprinting platform, to avoid such problems as recurrence of thrombus and restenosis of a lumen after the lumen tissue has been implanted for a long time, thereby improving the biological reliability of the lumen tissue.