Abstract: An object of the present invention is to provide a compound that has a specific chemical structure having an activation effect on SIRT6 and is useful as an active component for preventing and treating inflammatory diseases, and the present invention relates to a compound represented by Formula (1) or a pharmaceutically acceptable salt thereof, where each symbol in Formula (1) has the same definition as that described in the specification.

Abstract: An object of the present invention is to provide: a developer that can provide a thermosensitive recording material excellent in color development sensitivity and storage stability; and a thermosensitive recording material obtained using the developer. The object is achieved by a developer including a compound represented by the following Formula (1). In Formula (1), a, A, and L are as follows: a is an integer selected from 1 to 5, A is each independently a fluoro group or a perfluoroalkyl group, and L is any of functional groups represented by the following Formula (2): wherein in Formula (2), R is a C1-C4 alkyl group, and * represents a binding site to a sulfur atom in Formula (1).

Abstract: A printing device is configured to perform a plurality of print cycles including a plurality of conveying periods and a plurality of printing periods. An N-th print cycle includes: selecting m number of conveying periods from among the plurality of conveying periods; setting one or more valid conveying periods; obtaining a first time duration by dividing a time duration corresponding to the m number of conveying periods into a plurality of time segments; adjusting a time duration of each of the one or more valid conveying periods using the first time duration; outputting a pulse in each of the one or more valid conveying periods to convey the printing medium in response to a motor being driven to rotate upon receipt of the pulse; and printing a portion of an object on the printing medium in each of the plurality of the printing periods.

Abstract: A printing apparatus configured to print a label image on a medium, the medium on which the label image is printed including: a first end which is an upstream end of a tail region in a conveyance direction that is one of first printing regions in which one first character is lastly printed; and a second end which is an upstream end of a tail character in the conveyance direction that is the most upstream one of second characters printed in a second printing region, and wherein a controller is configured to cause a cutter to cut the medium at a first cutting target position located upstream of the first end when the first end is located more upstream than the second end and at a second cutting target position located upstream of the second end when the second end is located more upstream than the first end.

Abstract: A print control device includes a controller. The controller edits an image constituted by one or more objects including one or more upper objects, acquires an image area length, an image area width, a lower tape length, and a lower tape width, designates one upper object from among the one or more upper objects, and acquires an object area length, an object area width, and an upper tape width. In a case where a precondition is met for the designated upper object, the controller sets an orientation to a parallel orientation when a first condition or a third condition is met, and sets the orientation to an orthogonal orientation when a second condition or a fourth condition is met. The controller issues an error notification when the precondition is met but all of the first condition, the second condition, the third condition, and the fourth condition are not met.

Abstract: A printing device is configured to perform a plurality of print cycles including a plurality of conveying periods and a plurality of printing periods. An N-th print cycle includes: selecting m number of conveying periods from among the plurality of conveying periods; setting one or more valid conveying periods; obtaining a first time duration by dividing a time duration corresponding to the m number of conveying periods into a plurality of time segments; adjusting a time duration of each of the one or more valid conveying periods using the first time duration; outputting a pulse in each of the one or more valid conveying periods to convey the printing medium in response to a motor being driven to rotate upon receipt of the pulse; and printing a portion of an object on the printing medium in each of the plurality of the printing periods.

Abstract: A print control device includes a controller. The controller edits an image constituted by one or more objects including one or more upper objects, acquires an image area length, an image area width, a lower tape length, and a lower tape width, designates one upper object from among the one or more upper objects, and acquires an object area length, an object area width, and an upper tape width. In a case where a precondition is met for the designated upper object, the controller sets an orientation to a parallel orientation when a first condition or a third condition is met, and sets the orientation to an orthogonal orientation when a second condition or a fourth condition is met. The controller issues an error notification when the precondition is met but all of the first condition, the second condition, the third condition, and the fourth condition are not met.

Abstract: Provided is a novel compound or a salt thereof inhibiting MTHFD2 and useful for treating a disease caused by overexpression of MTHFD2, a disease involved in overexpression of MTHFD2 and/or a disease associated with overexpression of MTHFD2. Solution Provided is a sulfonamide derivative having a coumarin skeleton represented by the following formula (I) and having various substituents: wherein R1, R2, R3, R4, R5, R6 and R7 are the same as defined in the specification, and a salt thereof.

Abstract: A data generating apparatus includes a first storage storing a content having multiple regions, a second storage storing a parent-child relationship table, a first identifier configured to identify a target region, an updater configured to update the characters included in the target region, a changer configured to change the target region to a parent region corresponding to the target region when a carry occurs during updating, and a generator configured to generate print data of the content. The updater is configured to update the characters included in the changed target region, and the data generating apparatus further includes a second identifier configured to identify a deletion region, a first deleter configured to delete the deletion region from the content, and a second deleter configured to delete a parent region and a child region corresponding to the deletion region based on the parent-child relationship table of the deletion region.

Abstract: An editing device includes an adjuster configured to, with respect to a specific one of adjustment methods for each of blocks, determine a reduction rate at which a character size specified by setting size information associated with the specific adjustment method is reduced when the setting size information is changed to size information specifying a character size one-level smaller than the setting size information, among a plurality of pieces of size information associated with the specific adjustment method for each block in adjustment information, identify, as a reference reduction rate, a smallest one of the determined reduction rates for the character sizes each specified by the setting size information associated with the specific adjustment method for a corresponding block, and adjust the character size of one or more characters in each block with a specific reduction rate equal or approximated to the identified reference reduction rate.

Abstract: An editing apparatus, including a display and a controller configured to: obtain a size of a printing medium; obtain a layout, with respect to the printing medium, of a print object to be printed on the printing medium; obtain a length of a circumference of an adherend to which the printing medium is to be stuck; and execute a display control process of displaying, on the display, the layout such that an overlap portion and a non-overlap portion of the printing medium are distinguishable, the overlap portion being a portion of the printing medium which is covered, when the printing medium is stuck along the circumference of the adherend in order from one end to the other end of the printing medium in its specific direction, by a portion of the printing medium including the other end, the non-overlap portion being a portion of the printing medium except the overlap portion.

Abstract: A printing apparatus configured to print a label image on a medium, the medium on which the label image is printed including: a first end which is an upstream end of a tail region in a conveyance direction that is one of first printing regions in which one first character is lastly printed; and a second end which is an upstream end of a tail character in the conveyance direction that is the most upstream one of second characters printed in a second printing region, and wherein a controller is configured to cause a cutter to cut the medium at a first cutting target position located upstream of the first end when the first end is located more upstream than the second end and at a second cutting target position located upstream of the second end when the second end is located more upstream than the first end.

Abstract: Provided is a novel compound or a salt thereof inhibiting MTHFD2 and useful for treating a disease caused by overexpression of MTHFD2, a disease involved in overexpression of MTHFD2 and/or a disease associated with overexpression of MTHFD2. Solution Provided is a sulfonamide derivative having a coumarin skeleton represented by the following formula (I) and having various substituents: wherein R1, R2, R3, R4, R5, R6 and R7 are the same as defined in the specification, and a salt thereof.

Abstract: Provided is an agent for promoting growth of nonpathogenic oral indigenous bacteria, or an agent for improving oral bacterial flora, which comprises the dry powder of one or more mushrooms selected from the group consisting of Hericium erinaceus, Grifola frondosa, Lyophyllum shimeji, Hypsizygus marmoreus, Pleurotus ostreatus, Agaricus blazei, and Lentinula edodes, or an extract thereof, and which has an excellent growth-promoting effect on nonpathogenic oral indigenous bacteria and an excellent improving effect on oral bacterial flora, and which is effective in maintaining balanced indigenous bacterial flora. Also provided is a composition for oral use containing same.

Abstract: An editing apparatus, including a display and a controller configured to: obtain a size of a printing medium; obtain a layout, with respect to the printing medium, of a print object to be printed on the printing medium; obtain a length of a circumference of an adherend to which the printing medium is to be stuck; and execute a display control process of displaying, on the display, the layout such that an overlap portion and a non-overlap portion of the printing medium are distinguishable, the overlap portion being a portion of the printing medium which is covered, when the printing medium is stuck along the circumference of the adherend in order from one end to the other end of the printing medium in its specific direction, by a portion of the printing medium including the other end, the non-overlap portion being a portion of the printing medium except the overlap portion.

Abstract: A controller of a printing apparatus causes, in accordance with programs, the printing apparatus to obtain data and temporarily storing the received data in a buffer, create an image to be printed on a printing medium in accordance with the received data, obtain a receiving time period required to receive particular amount of data, obtain an image creating time period to create the image in accordance with the particular amount of data, obtain a total print length of a printing medium on which printing is executed in accordance with the data, calculate an amount of image which can be printed at a designated constant printing speed based on the receiving time period, the image creating time period and the total print length, and, when the calculated amount of image can be created, start a process of printing at the designated constant printing speed in accordance with the created image.

Abstract: A printing apparatus includes: a conveyor that conveys a medium including a base layer and a separation layer and including a first region, a second region, and a third region; a printer; and a controller. The controller is configured to control the printer to print a first mark on a portion of the medium in one of the first region and a first-region-side portion of the second region and to print a second mark on a portion of the medium in one of the third region and a third-region-side portion of the second region such that the first mark and the second mark are arranged in a line in the first direction.

Abstract: An editing device includes an adjuster configured to, with respect to a specific one of adjustment methods for each of blocks, determine a reduction rate at which a character size specified by setting size information associated with the specific adjustment method is reduced when the setting size information is changed to size information specifying a character size one-level smaller than the setting size information, among a plurality of pieces of size information associated with the specific adjustment method for each block in adjustment information, identify, as a reference reduction rate, a smallest one of the determined reduction rates for the character sizes each specified by the setting size information associated with the specific adjustment method for a corresponding block, and adjust the character size of one or more characters in each block with a specific reduction rate equal or approximated to the identified reference reduction rate.

Abstract: A printing apparatus includes: a conveyor configured to convey a medium including a transparent base layer and a separation layer stacked on each other, the medium further including a printing background layer; a printer configured to print a character on the medium conveyed by the conveyor, wherein the medium on which the character is printed is a printed medium; and a controller configured to control the conveyor and the printer. The controller is configured to: obtain outside-diameter relating information relating to an outside diameter of a wrapped member; and based on the obtained outside-diameter relating information, set a character printable region in which the printer is allowed to print the character on the printing background layer.

Abstract: A printer having multiple printing mechanisms has a printing device configured to execute a printing process to repetitively print a character defined for a page with one of the multiple printing mechanisms, and a controller. The controller is configured to determine, while the printing device is executing a first printing process which is the printing process for one page with use of the first printing mechanism, whether a first instruction to suspend the first printing process is received, print a page which is being printed when the first instruction is received to an end, and suspend the first printing process thereafter when the first instruction is received, determine whether a second instruction to start a second printing process with use of a second printing mechanism is received after the first printing process is suspended, and execute the second printing process when the second instruction is received.