Patents by Inventor Junyan Ji

Junyan Ji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions of mosunetuzumab and methods of use
    Patent number: 11958906
    Abstract: The disclosure provides pharmaceutical compositions comprising mosunetuzumab and methods of using the same.
    Type: Grant
    Filed: April 13, 2023
    Date of Patent: April 16, 2024
    Assignee: Genentech, Inc.
    Inventors: Junyan A. Ji, Jacqueline Yvonne Tyler
  • PHARMACEUTICAL COMPOSITIONS OF THERAPEUTIC PROTEINS AND METHODS OF USE
    Publication number: 20230406930
    Abstract: The disclosure provides pharmaceutical compositions of therapeutic proteins and methods of using the same.
    Type: Application
    Filed: April 13, 2023
    Publication date: December 21, 2023
    Inventors: Junyan JI, Ellen Dorothee MEUX, Satya Krishna Kishore RAVURI, Karin SCHOENHAMMER, Jacqueline Yvonne TYLER, Ilona Elisabeth VOLLRATH, Adithi Chandrasekhara BHARGAVA, Jeremy Jean-Pierre DUBOEUF
  • PHARMACEUTICAL COMPOSITIONS OF MOSUNETUZUMAB AND METHODS OF USE
    Publication number: 20230331861
    Abstract: The disclosure provides pharmaceutical compositions comprising mosunetuzumab and methods of using the same.
    Type: Application
    Filed: April 13, 2023
    Publication date: October 19, 2023
    Inventors: Junyan A. JI, Jacqueline Yvonne TYLER
  • Protein purification methods
    Patent number: 10906934
    Abstract: The invention provides methods of reducing fouling of ultrafiltration membranes in processes wherein virus particles are removed from aqueous solutions comprising virus particles and at least one protein by adding a surfactant or non-surfactant, non-ionic agent to the aqueous solution prior to filtration. The invention also provides methods to dissociate protein aggregates or to reduce the formation of protein aggregates by adding a surfactant or non-surfactant, non-ionic agent to the protein solution.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: February 2, 2021
    Assignee: GENENTECH, INC.
    Inventors: Arick Brown, Junyan Ji, Jun Liu, Yuchang John Wang
  • COMPOSITIONS AND METHODS USEFUL FOR STABILIZING PROTEIN-CONTAINING FORMULATIONS
    Publication number: 20200023063
    Abstract: The invention relates to use of non-surfactant compounds including, for example, polyoxyethylene (POE) sorbitans and polyethylene glycols (PEGs), for stabilizing protein-containing formulations and for the prevention of aggregation of proteins in such formulations.
    Type: Application
    Filed: September 27, 2019
    Publication date: January 23, 2020
    Applicant: Genentech, Inc.
    Inventors: Junyan JI, Jun LIU, Yuchang John WANG
  • COMPOSITIONS AND METHODS USEFUL FOR STABILIZING PROTEIN-CONTAINING FORMULATIONS
    Publication number: 20170224820
    Abstract: The invention relates to use of non-surfactant compounds including, for example, polyoxyethylene (POE) sorbitans and polyethylene glycols (PEGs), for stabilizing protein-containing formulations and for the prevention of aggregation of proteins in such formulations.
    Type: Application
    Filed: April 25, 2017
    Publication date: August 10, 2017
    Inventors: Junyan JI, Jun LIU, Yuchang John WANG
  • Compositions and methods useful for stabilizing protein-containing formulations
    Patent number: 9662395
    Abstract: The invention relates to use of non-surfactant compounds including, for example, polyoxyethylene (POE) sorbitans and polyethylene glycols (PEGs), for stabilizing protein-containing formulations and for the prevention of aggregation of proteins in such formulations.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: May 30, 2017
    Assignee: GENENTECH, INC.
    Inventors: Junyan Ji, Jun Liu, Yuchang John Wang
  • NOVEL PROTEIN PURIFICATION METHODS
    Publication number: 20140309403
    Abstract: The invention provides methods of reducing fouling of ultrafiltration membranes in processes wherein virus particles are removed from aqueous solutions comprising virus particles and at least one protein by adding a surfactant or non-surfactant, non-ionic agent to the aqueous solution prior to filtration. The invention also provides methods to dissociate protein aggregates or to reduce the formation of protein aggregates by adding a surfactant or non-surfactant, non-ionic agent to the protein solution.
    Type: Application
    Filed: March 23, 2012
    Publication date: October 16, 2014
    Applicant: GENENTECH, INC.
    Inventors: Arick Brown, Junyan Ji, Jun Liu, Yuchang John Wang
  • COMPOSITIONS AND METHODS FOR THE PREVENTION OF OXIDATIVE DEGRADATION OF PROTEINS
    Publication number: 20130171162
    Abstract: The invention relates to pharmaceutical formulations comprising a protein and free methionine in combination with one or more compounds capable of preventing the oxidation of aromatic amino acid residues within a protein. More specifically, the invention relates to stabilized, pharmaceutically effective preparations of oxidation-sensitive therapeutic agents. The invention further relates to a method of inhibiting the oxidation of such therapeutic agents.
    Type: Application
    Filed: June 28, 2012
    Publication date: July 4, 2013
    Inventors: JUNYAN A. JI, Yuchang John Wang, Boyan Zhang
  • COMPOSITIONS AND METHODS FOR THE PREVENTION OF OXIDATIVE DEGRADATION OF PROTEINS
    Publication number: 20100068210
    Abstract: The invention relates to pharmaceutical formulations comprising a protein and free methionine in combination with one or more compounds capable of preventing the oxidation of aromatic amino acid residues within a protein. More specifically, the invention relates to stabilized, pharmaceutically effective preparations of oxidation-sensitive therapeutic agents. The invention further relates to a method of inhibiting the oxidation of such therapeutic agents.
    Type: Application
    Filed: September 9, 2009
    Publication date: March 18, 2010
    Inventors: Junyan A. Ji, Yuchang John Wang, Boyan Zhang