Patents by Inventor Junying Yu

Junying Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Endothelial cell production by programming
    Patent number: 8785192
    Abstract: The invention generally regards methods for providing endothelial cells and precursors of endothelial cells from a variety of cell sources, such as pluripotent stem cells. Also provided are therapeutic compositions including the provided endothelial cells, and methods of using them for the treatment of subjects.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: July 22, 2014
    Assignee: Cellular Dynamics International, Inc.
    Inventors: Junying Yu, Maksym A. Vodyanyk
  • SOMATIC CELL REPROGRAMMING
    Publication number: 20140057355
    Abstract: The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method.
    Type: Application
    Filed: March 11, 2013
    Publication date: February 27, 2014
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: James A. Thomson, Junying Yu
  • HEMATOPOIETIC PRECURSOR CELL PRODUCTION BY PROGRAMMING
    Publication number: 20140037600
    Abstract: The invention generally regards methods for providing ematopoietic cells and precursors of hematopoietic cells from a variety of cell sources, such as pluripotent stem cells or somatic cells. Also provided are therapeutic compositions including the provided hematopoietic cells and precursors of hematopoietic cells, and methods of using such for the treatment of subjects.
    Type: Application
    Filed: February 7, 2012
    Publication date: February 6, 2014
    Applicant: CELLULAR DYNAMICS INTERNATIONAL, INC.
    Inventors: Junying Yu, Maksym A. Vodyanyk
  • HEPATOCYTE PRODUCTION BY FORWARD PROGRAMMING
    Publication number: 20130251694
    Abstract: The invention generally features methods for providing hepatocytes from a variety of cell sources, particularly pluripotent stem cells, therapeutic compositions featuring such cells, and methods of using them for the treatment of subjects.
    Type: Application
    Filed: June 5, 2013
    Publication date: September 26, 2013
    Applicant: CELLULAR DYNAMICS INTERNATIONAL, INC.
    Inventors: Junying YU, Fongching Kevin CHAU, Jinlan JIANG, Yong JIANG, Maksym A. VODYANYK
  • PLURIPOTENT STEM CELLS OBTAINED BY NON-VIRAL REPROGRAMMING
    Publication number: 20130217117
    Abstract: Methods for reprogramming primate somatic cells to pluripotency using an episomal vector that does not encode an infectious virus are disclosed. Pluripotent cells produced in the methods are also disclosed.
    Type: Application
    Filed: September 7, 2012
    Publication date: August 22, 2013
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: James Thomson, Junying Yu
  • SOMATIC CELL REPROGRAMMING
    Publication number: 20130210138
    Abstract: The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method.
    Type: Application
    Filed: February 13, 2013
    Publication date: August 15, 2013
    Inventors: James A. Thomson, Junying Yu
  • Hepatocyte production by forward programming
    Patent number: 8481317
    Abstract: The invention generally features methods for providing hepatocytes from a variety of cell sources, particularly pluripotent stem cells, therapeutic compositions featuring such cells, and methods of using them for the treatment of subjects.
    Type: Grant
    Filed: April 13, 2011
    Date of Patent: July 9, 2013
    Assignee: Cellular Dynamics International, Inc.
    Inventors: Junying Yu, Fongching Kevin Chau, Jinlan Jiang, Yong Jiang, Maksym A. Vodyanyk
  • Reprogramming somatic cells using retroviral vectors comprising Oct-4 and Sox2 genes
    Patent number: 8440461
    Abstract: The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: May 14, 2013
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: James A. Thomson, Junying Yu
  • OCT4 and SOX2 with SV40 T antigen produce pluripotent stem cells from primate somatic cells
    Patent number: 8268620
    Abstract: Methods for reprogramming primate somatic cells to pluripotency using an episomal vector that does not encode an infectious virus are disclosed. Pluripotent cells produced in the methods are also disclosed.
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: September 18, 2012
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: James Thomson, Junying Yu
  • Composition comprising recombinant nucleic acid encoding Sox2, Oct-4, Nanog and Lin28
    Patent number: 8183038
    Abstract: The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method.
    Type: Grant
    Filed: March 18, 2010
    Date of Patent: May 22, 2012
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: James A. Thomson, Junying Yu
  • ENDOTHELIAL CELL PRODUCTION BY PROGRAMMING
    Publication number: 20120009618
    Abstract: The invention generally regards methods for providing endothelial cells and precursors of endothelial cells from a variety of cell sources, such as pluripotent stem cells. Also provided are therapeutic compositions including the provided endothelial cells, and methods of using them for the treatment of subjects.
    Type: Application
    Filed: July 7, 2011
    Publication date: January 12, 2012
    Applicant: CELLULAR DYNAMICS INTERNATIONAL, INC.
    Inventors: Junying Yu, Maksym A. Vodyanyk
  • HEPATOCYTE PRODUCTION BY FORWARD PROGRAMMING
    Publication number: 20110280844
    Abstract: The invention generally features methods for providing hepatocytes from a variety of cell sources, particularly pluripotent stem cells, therapeutic compositions featuring such cells, and methods of using them for the treatment of subjects.
    Type: Application
    Filed: April 13, 2011
    Publication date: November 17, 2011
    Applicant: Cellular Dynamics International, Inc.
    Inventors: Junying Yu, Fongching Kevin Chau, Jinlan Jiang, Yong Jiang, Maksym A. Vodyanyk
  • EPISOMAL REPROGRAMMING WITH CHEMICALS
    Publication number: 20110104125
    Abstract: Methods and composition of induction of pluripotent stem cells are disclosed. For example, in certain aspects methods for generating essentially vector-free induced pluripotent stem cells with cell signaling regulators are described. Furthermore, certain aspects of the invention provide novel compositions comprising induced pluripotent stem cells essentially free of exogenous retroviral vector elements in the presence of a medium comprising signaling inhibitors. In certain aspects, feeder-free episomal reprogramming methods may be provided.
    Type: Application
    Filed: November 4, 2010
    Publication date: May 5, 2011
    Inventor: JUNYING YU
  • SOMATIC CELL REPROGRAMMING
    Publication number: 20110028537
    Abstract: The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method.
    Type: Application
    Filed: March 18, 2010
    Publication date: February 3, 2011
    Inventors: James A. Thomson, Junying Yu
  • PLURIPOTENT STEM CELLS OBTAINED BY NON-VIRAL REPROGRAMMING
    Publication number: 20100184227
    Abstract: Methods for reprogramming primate somatic cells to pluripotency using an episomal vector that does not encode an infectious virus are disclosed. Pluripotent cells produced in the methods are also disclosed.
    Type: Application
    Filed: October 23, 2009
    Publication date: July 22, 2010
    Inventors: James Thomson, Junying Yu
  • Generation of Clonal Mesenchymal Progenitors and Mesenchymal Stem Cell Lines Under Serum-Free Conditions
    Publication number: 20100015705
    Abstract: Methods for obtaining multipotent mesenchymal stem cells under serum-free conditions and methods for identifying multipotent mesenchymal progenitor cells are disclosed.
    Type: Application
    Filed: September 4, 2009
    Publication date: January 21, 2010
    Inventors: Maksym A. Vodyanyk, Junying Yu, James A. Thomson
  • Generation of clonal mesenchymal progenitors and mesenchymal stem cell lines under serum-free conditions
    Patent number: 7615374
    Abstract: Methods for obtaining multipotent mesenchymal stem cells under serum-free conditions and methods for identifying multipotent mesenchymal progenitor cells are disclosed.
    Type: Grant
    Filed: February 1, 2008
    Date of Patent: November 10, 2009
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Maksym A. Vodyanyk, Junying Yu, James A. Thomson, Igor I. Slukvin
  • GENERATION OF CLONAL MESENCHYMAL PROGENITORS AND MESENCHYMAL STEM CELL LINES UNDER SERUM-FREE CONDITIONS
    Publication number: 20090081784
    Abstract: Methods for obtaining multipotent mesenchymal stem cells under serum-free conditions and methods for identifying multipotent mesenchymal progenitor cells are disclosed.
    Type: Application
    Filed: February 1, 2008
    Publication date: March 26, 2009
    Inventors: Maksym A. Vodyanyk, Junying Yu, James A. Thomson, Igor I. Slukvin
  • SOMATIC CELL REPROGRAMMING
    Publication number: 20080233610
    Abstract: The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method.
    Type: Application
    Filed: March 21, 2008
    Publication date: September 25, 2008
    Inventors: James A. Thomson, Junying Yu