Abstract: The present invention relates to: a recombinant protein in which an interferon-beta mutein, in which an amino acid residue is substituted, and an antibody binding to a specific antigen are fused together; and a pharmaceutical composition for treating cancer, the composition comprising, as active ingredients, a polynucleotide, an expression vector and a recombinant microorganism, and the recombinant protein. In the recombinant protein, the physical properties of interferon-beta are improved through site-specific mutation, and thus the recombinant protein may have improved biological activity and purification efficiency, and the productivity thereof can be increased.

Abstract: A battery module including a plurality of cylindrical battery cells, a first frame having a receiving hole configured to receive the plurality of cylindrical battery cells, a second frame having a plurality of holes incised so as to each have a predetermined area in one side surface thereof, the second frame being coupled to the first frame is provided. A heat conduction pad located inside the second frame covers the plurality of holes. A receiving frame having a space portion for a heating solution and an operation unit configured to activate the heating solution and a heat conduction unit is also provided.

Abstract: Provided is a cartridge for moving an ultrasound focal point. The cartridge for moving an ultrasound focal point includes: a drive gear rotatably installed around a first axis; a driven gear configured to rotate around a second axis parallel to the first axis and move horizontally along the second axis at the same time by rotation power received from the drive gear; and an ultrasound irradiation moving body that is horizontally moved with the driven gear and vertically moved in a direction perpendicular to the first axis or the second axis. Thus, the ultrasound focal point can be stably moved in the horizontal and vertical directions, and thus the treatment efficiency can be improved.

Abstract: The inventive concept provides a substrate treating apparatus. The substrate treating apparatus includes a treating bath for liquid treating a plurality of substrates and having an accommodation space for accommodating a treating liquid; and a posture changing member for changing a posture of a substrate which is immersed in the treating liquid from a vertical posture to a horizontal posture.

Abstract: The disclosed display system may include a housing having an inner surface, and one or more display devices housed within the housing. The display system may also include a flexible heat spreader coupled to a surface of one of the display devices and the inner surface of the housing to thermally couple the display device to the housing. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: A method of providing information on medical personnel may be provided. The method according to an embodiment may include: receiving surgical information including information on a medical treatment department performing a surgery, information on an operating surgeon, surgical category information, and surgical code information; determining a score for each item that constitutes the surgical information on medical personnel on the basis of information on on-duty records of the medical personnel; determining a medical personnel score corresponding to the surgical information on the basis of a weighted value corresponding to the score for the each item; and providing information on the medical personnel that includes the medical personnel score.

Abstract: The present invention provides an apparatus for treating a substrate, the apparatus including: a processing tank having an accommodation space in which a processing liquid is accommodated; a support member for supporting at least one substrate in the receiving space in a vertical posture; and a posture changing robot for changing a posture of the substrate in a state of being immersed in the liquid state from the vertical posture to a horizontal posture, in which wherein the posture changing robot includes: a hand configured to grip the substrate; and an arm for moving the hand.

Abstract: The present invention relates to a dry powder formulation of interferon beta and a method for preparing same and, more specifically, to a dry powder formulation of interferon beta in the form of spherical particles having a high degree of morphological perfection, prepared by spray-drying a liquid composition containing interferon beta, and a method for preparing the dry powder formulation of interferon beta.

Abstract: A connecting apparatus for floating structures and a floating pier including the same with improved connection workability during installation or replacement of floating structures are disclosed. The floating pier includes a first floating structure including a plurality of first brackets, a first deck plate seated on the upper part of the plurality of first brackets, and a first buoyancy body penetrating the lower part of the plurality of first brackets; a second floating structure including a plurality of second brackets, a second deck plate seated on the upper part of the plurality of second brackets, and a second buoyancy body penetrating the lower part of the plurality of second brackets; and a connecting structure connecting the first floating structure and the second floating structure.

Abstract: The inventive concept provides a substrate treating apparatus. The substrate treating apparatus includes a batch-type treating bath for treating a substrate in a batch-type manner; a single-type treating chamber for treating the substrate in a single-type manner; and a buffer chamber positioned on a transfer path of the substrate transferred between the batch-type treating bath and the single-type treating chamber, and supplying a liquid for maintaining a wetting state of the substrate.

Abstract: The present invention provides an apparatus for treating a substrate, the apparatus including: a processing tank having an accommodation space in which a processing liquid is accommodated; a support member for supporting at least one substrate in the receiving space in a vertical posture; and a posture changing robot for changing a posture of the substrate in a state of being immersed in the liquid state from the vertical posture to a horizontal posture, in which wherein the posture changing robot includes: a hand configured to grip the substrate; and an arm for moving the hand.

Abstract: The present invention provides an apparatus for treating a substrate. The apparatus of processing a substrate includes: a treatment bath having an receiving space accommodating treatment liquid, and treating a plurality of substrates; and a supporting unit supporting the substrates in the treatment bath, wherein the supporting unit includes: a support having a first supporting rod supporting end portions of the substrates in a vertical state; and a fixing plate coupled to the support and fixing the support, a plurality of first slots in which edges of the substrates are inserted is formed at the first supporting rod, each of the plurality of first slots is defined by a first side, a second side facing the first side, and a bottom, a front and a rear of the first slot are open toward the receiving space, and the bottom of the first slot comprises contact protrusions protruding upward from a lower end of the first side of the first slot and supporting lower end portions of the substrates.

Abstract: The inventive concept provides a substrate treating apparatus. The substrate treating apparatus includes a treating bath having an accommodation space for accommodating a treating liquid; a support member configured to support at least one substrate in a vertical posture at the accommodation space; and a posture changing robot configured to change a posture of a substrate immersed in the treating liquid from the vertical posture to a horizontal posture, and wherein the posture changing robot comprises: a body configured to hold the substrate thereon; and a liquid supply member configured to supply a wetting liquid to the substrate placed on the body.

Abstract: The present invention relates to an RNA in-vitro transcript mRNA for intracellular expression of a gene of interest and a pharmaceutical composition comprising same for vaccines. When injected into animal cells, the in-vitro transcript mRNA including the gene of interest according to the present invention allows the protein of interest to be expressed in the animal cell in large quantities, and, as such, can be used as a gene vaccine against autoimmune diseases, infectious diseases, cancer- or tumor-related diseases, inflammatory diseases, and so on.

Abstract: A method and apparatus for an instant messaging service are disclosed. A method of displaying a message, performed by a terminal, includes receiving chat bubble data for the message from a server, identifying, based on the chat bubble data, an action of a user with respect to the message, and updating a display of the message based on the identified action and the chat bubble data.

Abstract: Disclosed are a salt (mesylate salt) of methanesulfonic acid and a triazolopyrazine derivative of formula (1), pharmaceutical compositions thereof, methods of making the salt, and therapeutic use thereof:

Abstract: The inventive concept provides a substrate treating apparatus. The substrate treating apparatus includes a liquid treating chamber; a support configured to support a substrate within the liquid treating chamber; a first treating liquid supply unit configured to supply a first treating liquid to the liquid treating chamber to treat the substrate with the first treating liquid; and a second treating liquid supply unit configured to supply a second treating liquid to the liquid treating chamber to treat the substrate with the second treating liquid, and wherein the second treating liquid supply unit includes a cooler for cooling the second treating liquid.

Abstract: The present invention relates to a method for preparing 4?-thio-5-aza-2?-deoxycytidine which exhibits DNMT1 inhibitory activity. The production method according to the present invention can enhance reaction efficiency through efficient process development and can stereoselectively prepare 4?-thio-5-aza-2?-deoxycytidine, and thus is economical and appropriate for mass production.

Abstract: The substrate processing apparatus includes a housing for providing a treatment space to treat a substrate; a support unit positioned in the treatment space and for supporting the substrate; a nozzle for supplying a treatment solution to the substrate supported on the support unit; and a heating unit for heating an edge region of the substrate supported on the support unit, in which the support unit includes a support plate on which the substrate is placed; a pin for supporting the substrate placed on the support plate; and a drive unit for rotating the support plate, and the heating unit includes an insertion body made of metal located within the chuck pin; and a magnet unit for heating the insertion body by an induction heating manner.

Abstract: The present invention relates to a prophylactic administration method against respiratory viruses, comprising administering interferon-beta to a potential respiratory virus-infected subject, and more specifically, to a method for restraining self-replication infection of respiratory viruses in a subject exposed to potential respiratory virus infection by administering interferon-beta as an active ingredient to respiratory cells through breathing in the manner of direct administration to cells infected with or potentially infected with a respiratory virus.