Patents by Inventor Junze HE

Junze HE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-aromatic amide compounds, preparation methods and uses thereof
    Patent number: 12358878
    Abstract: An N-aromatic amide compounds with formula (I) is disclosed. The definitions of R1, R2, R3, R4, R5, R6, W1, W2 and W3 in the formula are the same as those in the description.
    Type: Grant
    Filed: July 28, 2023
    Date of Patent: July 15, 2025
    Assignee: Shenzhen EDK Pharmaceutical Technology Co., Ltd.
    Inventors: Guohong Yang, Lijun Yu, Junze He, Meijuan Duan
  • N-AROMATIC AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF
    Publication number: 20230382870
    Abstract: An N-aromatic amide compounds with formula (I) is disclosed. The definitions of R1, R2, R3, R4, R5, R6, W1, W2 and W3 in the formula are the same as those in the description.
    Type: Application
    Filed: July 28, 2023
    Publication date: November 30, 2023
    Inventors: Guohong Yang, Lijun Yu, Junze He, Meijuan Duan
  • N-aromatic amide compounds, preparation methods and uses thereof
    Patent number: 11760727
    Abstract: The present invention relates to N-aromatic amide compounds with formula (I) and/or (II) and preparation methods therefor, pharmaceutical compositions and pharmaceutical formulations containing the compounds with formula (I) and/or (II), and use of the compounds with formula (I) and/or (II) in preparing a medicament for the treatment of diseases related to androgens. The definitions of R1, R2, R3, R4, R5, R6, W1, W2, W3, W4 and W5 in the formula are the same as those in the description. The compounds with the formula (I) and/or (II) are capable of binding to the androgen receptors and have activity for anti-androgen and degrading androgen receptor. The compounds can be used alone or as compositions for the treatment of various androgen-related diseases such as prostate cancer, prostate hyperplasia, breast cancer, bladder cancer, ovarian cancer and the like, and also for the treatment of acne, hirsutism, psilosis and other diseases.
    Type: Grant
    Filed: March 27, 2021
    Date of Patent: September 19, 2023
    Assignee: Shenzhen EDK Pharmaceutical Technology Co., Ltd.
    Inventors: Guohong Yang, Lijun Yu, Junze He, Meijuan Duan
  • N-AROMATIC AMIDE COMPUNDS, PREPARATION METHODS AND USES THEREOF
    Publication number: 20210214311
    Abstract: The present invention relates to N-aromatic amide compounds with formula (I) and/or (II) and preparation methods therefor, pharmaceutical compositions and pharmaceutical formulations containing the compounds with formula (I) and/or (II), and use of the compounds with formula (I) and/or (II) in preparing a medicament for the treatment of diseases related to androgens. The definitions of R1, R2, R3, R4, R5, R6, W1, W2, W3, W4 and W5 in the formula are the same as those in the description. The compounds with the formula (I) and/or (II) are capable of binding to the androgen receptors and have activity for anti-androgen and degrading androgen receptor. The compounds can be used alone or as compositions for the treatment of various androgen-related diseases such as prostate cancer, prostate hyperplasia, breast cancer, bladder cancer, ovarian cancer and the like, and also for the treatment of acne, hirsutism, psilosis and other diseases.
    Type: Application
    Filed: March 27, 2021
    Publication date: July 15, 2021
    Inventors: Guohong YANG, Lijun YU, Junze HE, Meijuan DUAN