Patents by Inventor Jurg R. Pfister

Jurg R. Pfister has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treprostinil derivative compounds and methods of using same
    Patent number: 11958822
    Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
    Type: Grant
    Filed: October 14, 2022
    Date of Patent: April 16, 2024
    Assignee: Corsair Pharma, Inc.
    Inventors: Cyrus K. Becker, Meenakshi S. Venkatraman, Xiaoming Zhang, Jürg R. Pfister, Gwenaella Rescourio
  • Treprostinil derivative compounds and methods of using same
    Patent number: 9845305
    Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable dosage. Transdermal applications can be used.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: December 19, 2017
    Assignee: CORSAIR PHARMA, INC.
    Inventors: Cyrus K. Becker, Jürg R. Pfister, Gwenaella Rescourio, Meenakshi S. Venkatraman, Xiaoming Zhang
  • TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME
    Publication number: 20170081303
    Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
    Type: Application
    Filed: October 18, 2016
    Publication date: March 23, 2017
    Inventors: Cyrus K. BECKER, Jürg R. PFISTER, Gwenaella RESCOURIO, Meenakshi S. VENKATRAMAN, Xiaoming ZHANG
  • Treprostinil derivative compounds and methods of using same
    Patent number: 9505737
    Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
    Type: Grant
    Filed: July 16, 2014
    Date of Patent: November 29, 2016
    Assignee: CORSAIR PHARMA, INC.
    Inventors: Cyrus K. Becker, Jürg R. Pfister, Gwenaella Rescourio, Meenakshi S. Venkatraman, Xiaoming Zhang
  • 7-AZONIABICYCLO[2.2.1]HEPTANE DERIVATIVES, METHODS OF PRODUCTION, AND PHARMACEUTICAL USES THEREOF
    Publication number: 20160296497
    Abstract: Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetylcholine receptor-mediated diseases, such as pulmonary diseases, are provided
    Type: Application
    Filed: January 14, 2016
    Publication date: October 13, 2016
    Inventors: Jürg R. PFISTER, Gwenaella RESCOURIO, Meenakshi S. VENKATRAMAN, Xiaoming ZHANG
  • Treprostinil derivative compounds and methods of using same
    Patent number: 9371264
    Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
    Type: Grant
    Filed: January 13, 2014
    Date of Patent: June 21, 2016
    Assignee: CORSAIR PHARMA, INC.
    Inventors: Cyrus K. Becker, Jürg R. Pfister, Gwenaella Rescourio, Meenakshi S. Venkatraman, Xiaoming Zhang
  • 7-azoniabicyclo[2.2.1]heptane derivatives, methods of production, and pharmaceutical uses thereof
    Patent number: 9320731
    Abstract: Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetylcholine receptor-mediated diseases, such as pulmonary diseases, are provided.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: April 26, 2016
    Assignee: THERON PHARMACEUTICALS, INC.
    Inventors: Jürg R. Pfister, Gwenaella Rescourio, Meenakshi S. Venkatraman, Xiaoming Zhang
  • TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME
    Publication number: 20150166503
    Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
    Type: Application
    Filed: July 16, 2014
    Publication date: June 18, 2015
    Inventors: Cyrus K. BECKER, Jürg R. PFISTER, Gwenaella RESCOURIO, Meenakshi S. VENKATRAMAN, Xiaoming ZHANG
  • TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME
    Publication number: 20140256730
    Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
    Type: Application
    Filed: January 13, 2014
    Publication date: September 11, 2014
    Applicant: Corsair Pharma, Inc.
    Inventors: Cyrus K. BECKER, Jürg R. PFISTER, Gwenaella RESCOURIO, Meenakshi S. VENKATRAMAN, Xiaoming ZHANG
  • 7-AZONIABICYCLO[2.2.1]HEPTANE DERIVATIVES, METHODS OF PRODUCTION, AND PHARMACEUTICAL USES THEREOF
    Publication number: 20140249195
    Abstract: Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetylcholine receptor-mediated diseases, such as pulmonary diseases, are provided
    Type: Application
    Filed: April 14, 2014
    Publication date: September 4, 2014
    Applicant: THERON PHARMACEUTICALS, INC
    Inventors: Jürg R. PFISTER, Gwenaella RESCOURIO, Meenakshi S. VENKATRAMAN, Xiaoming ZHANG
  • 7-azoniabicyclo[2.2.1]heptane derivatives, methods of production, and pharmaceutical uses thereof
    Patent number: 8742134
    Abstract: Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetylcholine receptor-mediated diseases, such as pulmonary diseases, are provided.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: June 3, 2014
    Assignee: Theron Pharmaceuticals, Inc.
    Inventors: Jurg R. Pfister, Gwenaella Rescourio, Meenakshi S. Venkatraman, Xiaoming Zhang
  • 7-azoniabicyclo [2.2.1] heptane derivatives, methods of production, and pharmaceutical uses thereof
    Patent number: 8742131
    Abstract: Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetyl-choline receptor-mediated diseases, such as pulmonary diseases, are provided.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: June 3, 2014
    Assignee: Theron Pharmaceuticals, Inc.
    Inventors: Jürg R. Pfister, Gwenaella Rescourio, Meenakshi S. Venkatraman, Xiaoming Zhang
  • 7-azoniabicyclo[2.2.1]heptane derivatives, methods of production, and pharmaceutical uses thereof
    Patent number: 8426611
    Abstract: Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetylcholine receptor-mediated diseases, such as pulmonary diseases, are provided.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: April 23, 2013
    Assignee: Theron Pharmaceuticals Inc.
    Inventors: Jürg R. Pfister, Gwenaella Rescourio, Meenakshi S. Venkatraman, Xiaoming Zhang
  • 7-AZONIABICYCLO [2.2.1] HEPTANE DERIVATIVES, METHODS OF PRODUCTION, AND PHARMACEUTICAL USES THEREOF
    Publication number: 20130059898
    Abstract: Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetyl-choline receptor-mediated diseases, such as pulmonary diseases, are provided.
    Type: Application
    Filed: January 27, 2011
    Publication date: March 7, 2013
    Applicant: Theron Pharmaceuticals, Inc.
    Inventors: Jürg R. Pfister, Gwenaella Rescourio, Meenakshi S. Venkatraman, Xiaoming Zhang
  • 4-substituted quinuclidine derivatives, methods of production, pharmaceutical uses thereof
    Patent number: 8114891
    Abstract: The present invention relates to compounds and formulations capable of affecting nicotinic acetylcholine receptors (nAChRs), for example, as modulators of specific nicotinic receptor subtypes (specifically, the alpha7 nAChR subtype). The present invention also relates to methods for treating a wide variety of conditions and disorders, particularly those associated with dysfunction of the central and autonomic nervous systems.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: February 14, 2012
    Assignee: CoMentis, Inc.
    Inventors: Jürg R. Pfister, Meenakshi S. Venkatraman, Xiaoming Zhang
  • 7-AZONIABICYCLO[2.2.1]HEPTANE DERIVATIVES, METHODS OF PRODUCTION, AND PHARMACEUTICAL USES THEREOF
    Publication number: 20120029044
    Abstract: Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetylcholine receptor-mediated diseases, such as pulmonary diseases, are provided.
    Type: Application
    Filed: January 27, 2011
    Publication date: February 2, 2012
    Inventors: Jürg R. Pfister, Gwenaella Rescourio, Meenakshi S. Venkatraman, Xiaoming Zhang
  • 4-SUBSTITUTED QUINUCLIDINE DERIVATIVES, METHODS OF PRODUCTION, AND PHARMACEUTICAL USES THEREOF
    Publication number: 20090088418
    Abstract: The present invention relates to compounds and formulations capable of affecting nicotinic acetylcholine receptors (nAChRs), for example, as modulators of specific nicotinic receptor subtypes (specifically, the alpha7 nAChR subtype). The present invention also relates to methods for treating a wide variety of conditions and disorders, particularly those associated with dysfunction of the central and autonomic nervous systems.
    Type: Application
    Filed: September 30, 2008
    Publication date: April 2, 2009
    Applicant: CoMentis, Inc.
    Inventors: Jurg R. Pfister, Meenakshi S. Venkatraman, Xiaoming Zhang
  • 5-HT3 receptor antagonists and methods of use
    Patent number: 7501436
    Abstract: The subject invention provides useful and novel 5-HT3 antagonists. The subject invention also provides methods for synthesizing the compounds of invention. The invention also provides methods for the treatment of irritable bowel syndrome and other such conditions.
    Type: Grant
    Filed: October 20, 2006
    Date of Patent: March 10, 2009
    Assignee: ARYx Therapeutics, Inc.
    Inventors: Xiaoming Zhang, Jurg R. Pfister, Cyrus Becker, Pascal Druzgala
  • Materials and Methods for Treating Coagulation Disorders
    Publication number: 20080221204
    Abstract: This invention is drawn to compounds which are more easily metabolized by the metabolic drug detoxification systems. Particularly, warfarin analogs which have been designed to include esters within the structure of the compounds are taught. The invention teaches methods of reducing the toxicity of drugs comprising the introduction of ester groups into drugs during the synthesis of the drug. This invention is also drawn to methods of treating coagulation disorders comprising the administration of compounds which have been designed to be metabolized by serum or intracellular hydrolases and esterases. Pharmaceutical compositions of the ester containing warfarin, analogs are also taught.
    Type: Application
    Filed: May 22, 2008
    Publication date: September 11, 2008
    Inventors: Pascal Druzgala, Xiaoming Zhang, Jurg R. Pfister
  • Materials and methods for treating hypercholesterolemia
    Patent number: 7384973
    Abstract: The subject invention provides novel HMG-CoA-reductase inhibitors. In a preferred embodiment, the HMG-CoA reductase inhibitors of the subject invention can be deactivated to a primary inactive metabolite by hydrolytic enzymes. Compounds of the present invention can be advantageously used to treat patients suffering hypercholesterolemia.
    Type: Grant
    Filed: September 6, 2005
    Date of Patent: June 10, 2008
    Assignee: ARYx Therapeutics, Inc.
    Inventors: Pascal Druzgala, Xiaoming Zhang, Jurg R. Pfister