Abstract: An insertion mechanism for a cannula includes a cannula housing, a displaceable cannula, at least one cannula holder, an insertion spring, a triggering element, and a safety device. The safety device, in a secured state, holds the triggering element in a blocked position against a force of the insertion spring and, in a released state, releases the triggering element such that the triggering element is movable into a release position by the force of said insertion energy store and the at least one cannula holder is able to move relative to the cannula housing, driven by the insertion energy store, so as to trigger or implement an insertion movement or insertion. To reach the released state, the safety mechanism is heatable by a heating element and softened and/or weakened with respect to its mechanical carrying or holding capacity, or severed or at least partially or completely melted.

Abstract: An insertion mechanism for a cannula includes a cannula housing, a displaceable cannula, at least one cannula holder, an insertion spring, a triggering element, and a safety device. The safety device, in a secured state, holds the triggering element in a blocked position against a force of the insertion spring and, in a released state, releases the triggering element such that the triggering element is movable into a release position by the force of said insertion energy store and the at least one cannula holder is able to move relative to the cannula housing, driven by the insertion energy store, so as to trigger or implement an insertion movement or insertion. To reach the released state, the safety mechanism is heatable by a heating element and softened and/or weakened with respect to its mechanical carrying or holding capacity, or severed or at least partially or completely melted.

Abstract: A modular device for administering a fluid medicament fixable to the skin of a user includes a reservoir module with a reservoir defining a first axis, a first connecting structure and a first electrical contact arrangement; and a pump module with a piston rod defining a second axis, a second connecting structure arranged around the piston rod, and a second electrical contact arrangement. The first and second connecting structures are plugged together and the first axis and the second axes lie on a common axis forming a rotational axis. The pump module is rotated relative to the reservoir module about this rotational axis to electrically connect the first and second electrical contact arrangements. The first contact arrangement is displaced radially farther from the first axis than the first connecting structure, and the second electrical contact arrangement is displaced radially farther from the second axis than the second connecting structure.

Abstract: Monitoring an injection process executed by a variable dose injection device with feedback means for generating a number of feedback events proportionate to the dose to be determined is disclosed. A dialed or injected dose is determined by measuring a first signal of the process comprising a first signal peak related to a feedback event; detecting the first signal peak in the first signal; selecting an evaluation interval comprising the detected peak and adapted to an expected peak duration; deriving, from the first signal limited to the evaluation interval, a feature or characterizing parameter of the feedback event; identifying, from the derived feature, the feedback event as one of a dial up, dial down, or expel feedback event, and counting identified feedback events to determine the dialed or the ejected dose. The two-stage approach with serially executed peak detection and peak identification allows to optimize data storage and processing power.

Abstract: An infusion apparatus for delivering medication includes a housing, a drive mechanism, a force sensor, and a transfer element. The drive mechanism comprises first and second conveying elements, the second conveying element for advancing a plug in a reservoir in the distal direction, the first conveying element with limited axial movement relative to the housing but rotatable to cause an ejecting or resetting movement of the second conveying element. The force sensor is arranged along a central axis between the housing and the proximal end of the drive mechanism. The transfer element is axially arranged between the force sensor and the first conveying element and the force sensor bears axial forces exerted by the ejection movement. The second conveying element moves the transfer element away from the first conveying element against the bias of a restoring force such that the force sensor bears axial forces exerted by the resetting movement.

Abstract: An infusion apparatus for delivering medication includes a housing, a drive mechanism, a force sensor, and a transfer element. The drive mechanism comprises first and second conveying elements, the second conveying element for advancing a plug in a reservoir in the distal direction, the first conveying element with limited axial movement relative to the housing but rotatable to cause an ejecting or resetting movement of the second conveying element. The force sensor is arranged along a central axis between the housing and the proximal end of the drive mechanism. The transfer element is axially arranged between the force sensor and the first conveying element and the force sensor bears axial forces exerted by the ejection movement. The second conveying element moves the transfer element away from the first conveying element against the bias of a restoring force such that the force sensor bears axial forces exerted by the resetting movement.

Abstract: An insertion mechanism for a cannula includes a cannula housing, a displaceable cannula, at least one cannula holder, an insertion spring, a triggering element, and a safety device. The safety device, in a secured state, holds the triggering element in a blocked position against a force of the insertion spring and, in a released state, releases the triggering element such that the triggering element is movable into a release position by the force of said insertion energy store and the at least one cannula holder is able to move relative to the cannula housing, driven by the insertion energy store, so as to trigger or implement an insertion movement or insertion. To reach the released state, the safety mechanism is heatable by a heating element and softened and/or weakened with respect to its mechanical carrying or holding capacity, or severed or at least partially or completely melted.

Abstract: The invention provides a injection device for administering an injectable product, including a base section adapted to receive a container from which a product dose is dispensed through a needle by displacement of a piston in the container, and a drive unit including a driven member, a drive element and a damping arrangement, the drive unit for applying a force to advance the piston in the container to dispense a dose, wherein the damping arrangement generally counteracts the drive force and counter forces. The invention also encompasses a needle safety sleeve and a blocking structure for use with injection devices.

Abstract: The invention provides a injection device for administering an injectable product, including a base section adapted to receive a container from which a product dose is dispensed through a needle by displacement of a piston in the container, and a drive unit including a driven member, a drive element and a damping arrangement, the drive unit for applying a force to advance the piston in the container to dispense a dose, wherein the damping arrangement generally counteracts the drive force and counter forces. The invention also encompasses a needle safety sleeve and a blocking structure for use with injection devices.

Abstract: The invention relates to a compact storage system and a corresponding method for storing frozen specimens. The compact storage system comprises one storage area, a housing with thermal insulation and at least one refrigeration unit, with which at least the storage area is coolable down to a temperature of at least ?15° C. The compact storage system also comprises storage shelves arranged completely within the refrigerated storage area and a transfer area arranged above this storage area. An essentially horizontally moving robot is arranged within the transfer area. The compact storage system is characterised in that it comprises at least one essentially vertical paternoster device, with a plurality of essentially horizontally oriented storage shelves circulating on an essentially oval path. The robot working in conjunction with the paternoster device is accomplished for removing or depositing a storage shelf and/or objects from/onto a storage shelf respectively.

Abstract: The invention provides a injection device for administering an injectable product, including a base section adapted to receive a container from which a product dose is dispensed through a needle by displacement of a piston in the container, and a drive unit including a driven member, a drive element and a damping arrangement, the drive unit for applying a force to advance the piston in the container to dispense a dose, wherein the damping arrangement generally counteracts the drive force and counter forces. The invention also encompasses a needle safety sleeve and a blocking structure for use with injection devices.

Abstract: The invention provides a injection device for administering an injectable product, including a base section adapted to receive a container from which a product dose is dispensed through a needle by displacement of a piston in the container, and a drive unit including a driven member, a drive element and a damping arrangement, the drive unit for applying a force to advance the piston in the container to dispense a dose, wherein the damping arrangement generally counteracts the drive force and counter forces. The invention also encompasses a needle safety sleeve and a blocking structure for use with injection devices.

Abstract: The invention provides a injection device for administering an injectable product, including a base section adapted to receive a container from which a product dose is dispensed through a needle by displacement of a piston in the container, and a drive unit including a driven member, a drive element and a damping arrangement, the drive unit for applying a force to advance the piston in the container to dispense a dose, wherein the damping arrangement generally counteracts the drive force and counter forces. The invention also encompasses a needle safety sleeve and a blocking structure for use with injection devices.

Abstract: The invention provides a injection device for administering an injectable product, including a base section adapted to receive a container from which a product dose is dispensed through a needle by displacement of a piston in the container, and a drive unit including a driven member, a drive element and a damping arrangement, the drive unit for applying a force to advance the piston in the container to dispense a dose, wherein the damping arrangement generally counteracts the drive force and counter forces. The invention also encompasses a needle safety sleeve and a blocking structure for use with injection devices.

Abstract: The invention provides a injection device for administering an injectable product, including a base section adapted to receive a container from which a product dose is dispensed through a needle by displacement of a piston in the container, and a drive unit including a driven member, a drive element and a damping arrangement, the drive unit for applying a force to advance the piston in the container to dispense a dose, wherein the damping arrangement generally counteracts the drive force and counter forces. The invention also encompasses a needle safety sleeve and a blocking structure for use with injection devices.

Abstract: An injection device includes a timing device that is triggered by an injection. After a predetermined period of time, the timing device triggers a sensing device that produces a signal, such as an audible tone. The signal alerts the user that a sufficient amount of time has passed and the injection device can be removed.

Abstract: The present invention provides an auto-injection device including a housing, a container from which a product is dispensed by advancing a piston, the container shiftably accommodated by the housing and carrying a needle, and a drive unit including a driven member, wherein the driven member is shiftably accommodated by the housing and, during an auto-injection, is adapted for inserting the needle and advancing the container to a predetermined frontal position in relation to the housing and advancing the piston within the container for dispensing of the product, wherein the driven member remains uncoupled with the piston until the container reaches its frontal position, and upon the container reaching its frontal position, the driven member detaches from the container and couples with the piston for advancing the piston within the container.

Abstract: The present invention provides an infusor including a housing, a reservoir accommodated in the housing for containing a product fluid to be administered, and a delivery means accommodated in the housing for an automatic dosed delivery of the product fluid from the reservoir, wherein the reservoir includes at least two separate fluid spaces having separate fluid outlets.

Abstract: A resettable display of a device for metered administration of a fluid drug, comprising a housing, a fluid container containing the fluid and provided in or on said housing, an actuating device shiftably mounted by a length in or on said housing, which, upon actuation, shifts a piston in the fluid container in order to displace from the fluid container a fluid dose adjusted by the actuating device, a display provided in or on said housing displaying a measure for the adjusted fluid dose, and a resetting means shifted with the actuating device and thus resetting the display. The display comprises a minimum of one counter ring rotated from a zero position when adjusting the fluid dose by means of the actuating device in relation to the housing. The resetting means mechanically transfers the shift movement of the actuating device into a reverse rotary movement of the counter ring towards its zero position (FIG. 1).

Abstract: The present invention provides an auto-injection device including a housing, a container from which a product is dispensed by advancing a piston, the container shiftably accommodated by the housing and carrying a needle, and a drive unit including a driven member, wherein the driven member is shiftably accommodated by the housing and, during an auto-injection, is adapted for inserting the needle and advancing the container to a predetermined frontal position in relation to the housing and advancing the piston within the container for dispensing of the product, wherein the driven member remains uncoupled with the piston until the container reaches its frontal position, and upon the container reaching its frontal position, the driven member detaches from the container and couples with the piston for advancing the piston within the container.