Abstract: The present invention relates generally to pyrrolidine and thiazolidine DPP-IV inhibitor compounds. The present invention also provides synthetic methods for preparation of such compounds, methods of inhibiting DPP-IV using such compounds and pharmaceutical formulations containing them for treatment of DPP-IV mediated diseases, in particular, Type-2 diabetes.

Abstract: The present invention relates generally to pyrrolidine and thiazolidine DPP-IV inhibitor compounds. The present invention also provides synthetic methods for preparation of such compounds, methods of inhibiting DPP-IV using such compounds and pharmaceutical formulations containing them for treatment of DPP-IV mediated diseases, in particular, Type-2 diabetes.

Abstract: The present invention relates generally to pyrrolidine and thiazolidine DPP-IV inhibitor compounds. The present invention also provides synthetic methods for preparation of such compounds, methods of inhibiting DPP-IV using such compounds and pharmaceutical formulations containing them for treatment of DPP-IV mediated diseases, in particular, Type-2 diabetes.

Abstract: Composites and methods useful for oxygen sorption and other uses are presented, the composites comprising: (A) one or more crystalline ceramic oxides selected from compounds within general formula (1): AxA?x?ByB?y?O3-? and ??(1) (B) one or more crystalline ceramic oxides selected from compounds within general formulas (2), (3), (4), (5), (6), (7), and (8): A2BO4-???(2) A2B2O5-???(3) AO(ABO3-?)n??(4) AM2Cu3O7-???(5) Bi4V2(1-x)Me2xO11-3x,??(6) A?B?O3??(7) A2B2O7-?.

Abstract: Compositions and methods useful for oxygen sorption and other uses are presented, the compositions A composite material comprising components (A) and (B), wherein component (A) is selected from crystalline ceramic materials capable of forming a stable, reversible perovskite crystal phase at elevated temperatures (T>500° C.), and combinations thereof, and component (B) comprises a metal selected from rhodium (Rh), platinum (Pt), palladium (Pd), nickel (Ni) and silver (Ag), and combinations and alloys of these metals.

Abstract: The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 inhibitors.

Abstract: The present invention relates generally to pyrrolidine and thiazolidine DPP-IV inhibitor compounds. The present invention also provides synthetic methods for preparation of such compounds, methods of inhibiting DPP-IV using such compounds and pharmaceutical formulations containing them for treatment of DPP-IV mediated diseases, in particular, Type-2 diabetes.

Abstract: Compositions and methods useful for oxygen sorption and other uses are presented, the compositions being within the general formulas (1), (2), (3), and (4): AxByO3-?, ??(1) AxA?x?ByB?y?O3-?, and ??(2) AxA?x?A?x?ByB?y?B?y?O3-?, ??(3) MOn ??(4) and combinations thereof, especially those where the B sites are independently selected from cations of the d block transition metals Cr, Mn, Fe, Co, Ni, and Cu. One desirable set of compositions of the invention are combinations of any one or more of the compounds of generals formulas (1), (2), or (3) with one or more compounds of the general formula (4). In combination with an active support or matrix oxide within general formulas (1), (2), and (3), stability of the binary metal oxides within general formula (4) can be enhanced, while extending the oxygen sorption/desorption capacities of the matrix oxide.

Abstract: Composites and methods useful for oxygen sorption and other uses are presented, the composites comprising: (A) one or more crystalline ceramic oxides selected from compounds within general formula (1): AxA?x?ByB?y?O3-???(1) and (B) one or more crystalline ceramic oxides selected from compounds within general formulas (2), (3), (4), (5), (6), (7), and (8): A2BO4-???(2) A2B2O5-???(3) AO(ABO3-?)n ??(4) AM2Cu3O7-???(5) Bi4V2(1-x)Me2xO11-3x, ??(6) A?B?O3 ??(7) A2B2O7-???(8)

Abstract: Compositions and methods useful for oxygen sorption and other uses are presented within the general formulas (1), (2), (3), (4), (5), (6), and (7): A2BO4?? (1) A2B2O5?? (2) AO(ABO3??)n (3) AM2Cu3O7?? (4) Bi4V2(1?x)Me2xO11?3x, (5) A?B?O3 where B? is W or Mo; (6) A2B2O7??, (7) and combinations thereof, wherein: A is a cation of atoms having atomic numbers ranging from 57-71, inclusive, a cation of yttrium, cations of Groups 1 and 2 atoms, and combination thereof; B is a cation of a d-block transition metal; A? is a cation of Na or Li; M is a metal cation selected from cations of Group 2 atoms; Me is a metal cation of Cu, Bi, and Co atoms; x ranges from 0.01 to 1.00; and ? ranges from 0.05 to 0.30. The compounds (1)-(7) may function as active supports for binary metal oxides to enhance the oxygen sorption/desorption capacity of the composites.

Abstract: Compositions and methods useful for oxygen sorption and other uses are presented, the compositions A composite material comprising components (A) and (B), wherein component (A) is selected from crystalline ceramic materials capable of forming a stable, reversible perovskite crystal phase at elevated temperatures (T>500° C.), and combinations thereof, and component (B) comprises a metal selected from rhodium (Rh), platinum (Pt), palladium (Pd), nickel (Ni) and silver (Ag), and combinations and alloys of these metals.