Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3and R4 are as defined herein.

Abstract: Methods of treating an inflammatory disorder include administering an effective amount of a compound represented by Structural Formula (I): Ring A is optionally substituted, contains zero, one, two, or three double bonds, and is optionally fused to an aliphatic, aryl or heteroaryl ring; X is an optionally substituted 1 to 3 carbon aliphatic chain that is optionally fused to a monocyclic, optionally substituted, aliphatic, heterocyclic, aryl, or heteroaryl ring, wherein one or two carbons in X are optionally replaced with —O—, —S—, or —NRe—; Y is carbon or nitrogen; R1 and R2 are independently —H, —OH, —CN, —NO2, —NRfRg, halogen, optionally substituted alkyl, or optionally substituted alkoxy; or R1 and R2 together link the carbons to which they are bonded with a bond, —O—, —S—, or —NRh—; R3 and R4 are independently —H, —OH, —CN, —NO2, —NRiRj, halogen, optionally substituted alkyl, or optionally substituted alkoxy, or R4 is ?O; or R3 and R4, taken together with the atoms to which they are bonded, form a

Abstract: The invention relates to compositions to be administered to a living being, a method for marking agents that are administered to living beings, the use thereof, and an accelerated test.

Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3 and R4 are as defined herein.

Abstract: The present invention relates to novel recombinant vaccines providing protective immunity against tuberculosis. Further, the present invention refers to novel recombinant nucleic acid molecules, vectors containing said nucleic acid molecules, cells transformed with said nucleic acid molecules and polypeptides encoded by said nucleic acid molecules.

Abstract: A microtome comprising a knife holding device for a cutting element (16) and comprising a specimen holding device (12) for a specimen which is to be cut thin is described. Associated with the specimen holding device (12) for performing a cutting movement is a first drive device (18) and associated with the specimen holding device (12) or the knife holding device is a second drive device (38) for performing a feed movement. A sender (20) is associated with the first drive device (18). The sender (20) is connected with an electronic control means (28). Control of the first drive device (18) is effected by means of a first operating element (28). Control of the second drive device (38) is effected by means of a second operating element (44). To achieve an excellent degree of operating comfort for the microtome the first operating element (28) has two control modes, namely a standard mode and a second mode.

Abstract: The present invention relates to novel recombinant vaccines providing protective immunity against tuberculosis. Further, the present invention refers to novel recombinant nucleic acid molecules, vectors containing said nucleic acid molecules, cells transformed with said nucleic acid molecules and polypeptides encoded by said nucleic acid molecules.

Abstract: An inductive sensor on the basis of an annularly closed, soft-magnetic core (K) is disclosed wherein the current to be measured produces an inductive change within the annularly closed magnetic circuit, said inductive change being taken via a measurement winding (MW) wrapped around the core. In order to achieve a linear behavior within a broad range of measurement, the annularly closed core comprises core regions (KB) that comprise a magnetic composite powder material and, in particular, a ferrite polymer composite material (FPC).

Abstract: The present invention relates to novel recombinant vaccines providing protective immunity against tuberculosis. Further, the present invention refers to novel recombinant nucleic acid molecules, vectors containing said nucleic acid molecules, cells transformed with said nucleic acid molecules and polypeptides encoded by said nucleic acid molecules.

Abstract: The invention relates to a method for inputting information into a mobile radio telephone (1) via its input data channel by appropriately moving a motion detector (10) which belongs to the radio telephone (1) and senses this movement. In this arrangement, the mobile radio telephone (1) can be constructed to be pen-shaped and can contain the motion detector (10) in its pen point.

Abstract: The invention relates to a method for inputting information into a mobile radio telephone (1) via its input data channel by appropriately moving a motion detector (10) which belongs to the radio telephone (1) and senses this movement. In this arrangement, the mobile radio telephone (1) can be constructed to be pen-shaped and can contain the motion detector (10) in its pen point.

Abstract: The invention relates to a process for cooling polymerization reactors in the preparation of polyolefins, the polymerization being carried out in a first reactor and in at least one further reactor, the further reactor or reactors being connected downstream of the first reactor and each being cooled by an internal cooling circuit in which a cooling medium circulates. The invention comprises feeding cooling medium from the cooling circuit (9) of the first reactor (1) into the cooling circuit (10) of at least one further reactor (2) and taking off the same amount of cooling medium from the cooling circuit (10) of this reactor (2), cooling it and recirculating it into the cooling circuit (9) of the first reactor (1).

Abstract: In order to inspect at least one antenna branch (A1, A2, . . . An), in particular in a vehicle, a power level to be radiated is initially fed into the antenna branch, after which a power level which is reflected in the antenna branch is sensed. Then, a relationship is formed between the fed-in power level and the reflected power level in order to obtain a quality signal indicating the quality of the antenna branch. This procedure can be carried out successively when there are a plurality of antenna branches, in order to select, as a function of the respective quality signal, that antenna branch at which the reflected power level is lowest. In this way, on the one hand, it is possible to check the matching of the antenna branches while, on the other hand, it is possible to ensure that, for example when specific antenna branches are damaged, it is always possible to find other antenna branches for satisfactory communication.

Abstract: A method for adjusting the frequency of an oscillator for a receiver circuit comprising: downconverting a received signal to generate a downconverted signal, counting the number of zero crossings of the downconverted signal over a predefined time interval, determining a correction number of zero crossings based on the data of the downconverted signal over the predefined time interval, determining a corrected number of zero crossings for the received signal based on the counted number of zero crossings and the correction number of zero crossings, adjusting the frequency of the oscillator based on the corrected number of zero crossings.

Abstract: Bending elements for the triggering indicator of a belt tensioner.The triggering indicator for belt tensioners in motor vehicles includes a helical bending element made of a thermoplastic material such as polyamide, polyester or polyacetal.

Abstract: A device for lifting one or more flexible, flat parts such as stacked pap pasteboard, cardboard, plastic is disclosed. The device relies on the propensity of a bundle of such parts to flex up around its edge when compressed at a point away from that edge. In one embodiment, a compression device presses down on one bundle in a stack of several bundles of parts to be lifted and a second compression device presses down the underlying stack, thus opening up a gap between the upper bundle and lower stack. A lifting arm is driven into this gap, and a clamp presses down on the bundle above the lifting arm, grasping the bundle. Two retainers are extended down onto the lower stack to prevent the stack from moving as the bundle is lifted. Once contact between the lifted bundle and the remaining stack is broken, the retainers are withdrawn and the lifting device is maneuvered to a delivery position.

Abstract: A heating system for a passenger compartment of a motor vehicle includes a heat exchanger located in the passenger compartment and a feeding conduit extending between the heat exchanger and the cooling circuit of the vehicle internal combustion engine and connected to the cooling circuit at a point downstream of the internal combustion engine in a direction of liquid flow. A return conduit extends between the heat exchanger and a delivery unit of the cooling circuit. The heating system also includes a shut-off device for blocking flow of heat to the heat exchanger. The shut-off device has first and second chambers and inlet and outlet ports communicating with the first chamber. A pressure port communicates with the second chamber and is connected with the feeding conduit. A wall separates the first and second chambers.

Abstract: A central locking system for use in a motor vehicle includes a pressure source generating preferably an under pressure and an over pressure. The source is connected to a series of pneumatic control units each including a pressure chamber, a control element arranged in the chamber for movement between two control positions, an opening in the chamber communicating with a space enclosing a valve which normally closes the opening and the space being provided with a discharging nipple which is coupled via the subsequent series connected control units to an indicator device. The indicator device is arranged in the field of view of the car operator. In this manner, the operating condition of locking devices which are outside of view of the operator can be reliably checked.

Abstract: A housing surrounds a compressor for cooling media and forms at one axial end of the same a chamber which receives from the compressor one or more streams of gaseous cooling medium in which compressor lubricating oil is entrained. The chamber communicates with an outlet of the housing and is filled with a body of gas-permeable material through which the stream or streams must pass on the way to the outlet, and which separates entrained oil from the gaseous cooling medium.

Abstract: The cooling system includes a cyclically operating cooling-medium compressor driven by the vehicle engine. At low to medium engine speeds, corresponding to speeds from idling to city-driving speeds, the cooling system develops a cooling power sufficient to satisfactorily cool the interior of the passenger compartment. At higher engine speeds, corresponding to highway travel, the cooling power developed by the cooling system is automatically decreased by automatically decreasing the per-cycle volumetric throughput of the cooling-medium compressor. The automatic decrease is effected in automatic response to the reaching of a certain engine rpm or a certain condensation pressure in the condenser of the cooling system. In the illustrated embodiment, the compressor is a sliding-vane compressor, and the per-rotation volumetric throughput thereof is decreased by arresting certain ones of the vanes in the retracted position.