Patents by Inventor Jurgen K. Sandow

Jurgen K. Sandow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5091365
    Abstract: The invention relates to the use of aids of the general formula ##STR1## in which B denotes a basic amino acid, A/B denotes an acidic or basic amino acid, X denotes a neutral and hydrophilic amino acid, L denotes a lipophilic neutral amino acid, and R denotes hydrogen or an acyl radical, or the physiologically tolerated salts thereof, for promoting the absorption of peptides and proteins on administration onto the mocosa, as well as to pharmaceutical compositions which contain a pharmacologically effective amount of one or more peptides or proteins as well as an aid of the abovementioned formula.
    Type: Grant
    Filed: August 5, 1988
    Date of Patent: February 25, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Jurgen K. Sandow, Rainer Schmiedel, Klaus Wirth, Hans P. Merkle, Suzanne Raehs
  • Patent number: 5091367
    Abstract: The invention relates to peptides of the formula ##STR1## in which X is absent or is hydrogen or acyl; A is Pgl, de-hydro-Pro, Pro, D-Thi or D-Pgl or represents optionally substituted D-Nal(2), D-Phe or D-Trp; B is His or optionally substituted D-Phe; C is Trp, D-Thi, D-Pal(3) or optionally substituted D-Trp; D is Tyr, Arg of His; E is D-Ser(R.sup.1), .beta.-Asn, .beta.-Asp-OMe, D-Thi or --NH--CH(CH.sub.2 R.sup.2)--CO--; F is Ser(R.sup.1), Leu, Trp or Phe; G is Gly-NH.sub.2, Aza-Gly-NH.sub.2, D-Ala-NH.sub.2 or NH-alkyl; R.sup.1 is glycosyl and R.sup.2 is hydrogen, acyl, aryl or heteroaryl.The invention also relates to methods for the preparation of these peptides, agents containing them and their use.
    Type: Grant
    Filed: June 28, 1991
    Date of Patent: February 25, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Wolfgang Konig, Jurgen K. Sandow, Cenek Kolar
  • Patent number: 5071836
    Abstract: Peptides of the formulaAc-D-Nal(2)-D-Phe-D-Phe-Ser-X-D-Ser(Rha)-Leu-Arg-Pro-Yin which X represents Tyr or His and Y represents Gly-NH.sub.2, D-Ala-NH.sub.2, Azgly-NH.sub.2 or NH--C.sub.2 H.sub.5 are competitive antagonists of Gn-RH. They are used for the treatment of gonadotropin- and steroid-dependent diseases and are prepared by known methods of peptide chemistry.
    Type: Grant
    Filed: December 12, 1989
    Date of Patent: December 10, 1991
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Cenek Kolar, Wolfgang Konig, Jurgen K. Sandow
  • Patent number: 4941874
    Abstract: The invention relates to a device for the injection of implants, preferably implants "in the form of small rods" (called rods), which are used for the long-term treatment of diseases, whose essential features are the completely transparent construction, especially of the injector body (3), as well as a protecting device which prevents the plunger rod from falling out, and a protective cap (6) for the plunger rod.
    Type: Grant
    Filed: August 9, 1988
    Date of Patent: July 17, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Jurgen K. Sandow, Wilfried De Felice, Horst Pajunk, Heinrich Pajunk
  • Patent number: 4621073
    Abstract: The invention relates to cyclic hexapeptides of the general formula III ##STR1## in which X represents the radical of an L-aminoacid of the general formula IIIa ##STR2## in which A and B are identical or different and denote alkyl having 1 to 3 carbon atoms, or A and B together represent a saturated, unsaturated or aromatic monocyclic or bicyclic structure having 3 to 6 carbon atoms, n denotes 0 or 1, and Y represents an aliphatic or aromatic L-aminoacid the side chain of which can be hydroxylated, and their salts with physiologically tolerated acids, and to a process for their preparation and their use and their intermediates.
    Type: Grant
    Filed: January 31, 1984
    Date of Patent: November 4, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Axel Friedrich, Wolfgang Konig, Volker Teetz, Rolf Geiger, Jurgen K. Sandow
  • Patent number: 4395400
    Abstract: What are disclosed are a nonapeptide of the formula ##STR1## wherein D-Aad (OBu.sup.t) represents D-.alpha.-aminoadipic acid .delta.-tert. butyl ester, methods for making this peptide, pharmaceutical preparations containing this peptide, and methods for its use in increasing fertility or for contraception.
    Type: Grant
    Filed: June 1, 1981
    Date of Patent: July 26, 1983
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Wolfgang Konig, Rolf Geiger, Jurgen K. Sandow
  • Patent number: 4377575
    Abstract: What is disclosed are steroid-21-halogeno-17-(alkyl carbonates), useful as medicaments for the treatment of inflammatory dermatoses, and a method for making them.
    Type: Grant
    Filed: December 15, 1980
    Date of Patent: March 22, 1983
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Ulrich Stache, Werner Fritsch, Hans G. Alpermann, Jurgen K. Sandow
  • Patent number: 4263282
    Abstract: What is disclosed in a method of inducing a contraceptive effect in a mammal by administering a contraceptively effective amount of a peptide of the formula ##STR1## in which X stands for D-serine-tert.butyl ether or D-glutamic acid .gamma.-cyclohexylamide.
    Type: Grant
    Filed: November 20, 1979
    Date of Patent: April 21, 1981
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Marianne von der Ohe, Jurgen K. Sandow, Wolfrad von Rechenberg
  • Patent number: 4003884
    Abstract: Peptides having LH-RH/FSH-RH activity useful for treatment of male and female sterility.
    Type: Grant
    Filed: May 16, 1975
    Date of Patent: January 18, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Wolfgang Konig, Rolf Geiger, Jurgen K. Sandow