Patents by Inventor Jurgen Michaelis

Jurgen Michaelis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the treatment or prevention of eczema/dermatitis
    Patent number: 5798335
    Abstract: The present invention provides a method for the treatment or prevention of eczema/dermatitis. This method involves the administration of Peptide T or its derivatives or analogues. Preferred compounds used in the method include: 1) D-Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr-NH.sub.2 ; 2) Ala-Ser-thr-thr-Thr-Asn-Tyr-Thr, 3) D-Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr, 4) D-Ala-Ala-Ser-Ser-Asn-Tyr-Met; 5) Thr-Asp-Asn-Tyr-Thr, 6) Thr-Thr-Ser-Tyr-Thr, 7) Thr-Thr-Asn-Tyr-Thr, 8) D-Thr-Thr-Tyr-D-Thr, 9) D-Ala-Ser-D-Thr-Thr-D-Thr-Asn-Tyr-D-Thr-NH.sub.2 ; 10) D-Ser-Ser-D-Thr-Thr-D-Thr-Thr-Tyr-D-Thr-NH.sub.2.
    Type: Grant
    Filed: May 7, 1996
    Date of Patent: August 25, 1998
    Assignee: Peptide Technology Limited
    Inventors: Jurgen Michaelis, Timothy Elliot Trigg
  • Treatment or prevention of Crohn's disease and/or ulcerative colitis
    Patent number: 5795858
    Abstract: The present invention provides a method for the treatment or prevention of Crohn's disease and/or ulcerative colitis. The method involves the administration of Peptide T or its derivatives or analogues. Preferred compounds used in the method include:1. D--Ala--Ser--Thr--Thr--Thr--Asn--Tyr--Thr--NH.sub.22. Ala--Ser--Thr--Thr--Thr--Asn--Tyr--Thr3. D--Ala--Ser--Thr--Thr--Thr--Ans--Tyr--Thr4. D--Ala--Ala--Ser--Ser--Ser--Asn--Tyr--Met5. Thr--Asp--Asn--Tyr--Thr6. Thr--Thr--Ser--Tyr--Thr7. Thr--Thr--Asn--Tyr--Thr8. D--Thr--Thr--Tyr--D--Thr9. D--Ala--Ser--D--Thr--Thr--D--Thr--Asn--Tyr--D--Thr--NH.sub.210. D--Ser--Ser--D--Thr--Thr--D--Thr--Thr--Tyr--D--Thr--NH.sub.
    Type: Grant
    Filed: March 31, 1995
    Date of Patent: August 18, 1998
    Assignee: Peptide Technology Limited
    Inventors: Jurgen Michaelis, Merilyn J. Sleigh
  • Method for the treatment of the complications and pathology of diabetes
    Patent number: 5561110
    Abstract: The present invention provides a method for the treatment of the complications and pathology of diabetes. The method involves the administration to a diabetic subject of a composition comprising a compound selected from the group consisting of (.beta.-Ala-His).sub.n, (Lys-His).sub.n, a compound of the formula R.sub.1 -X-R.sub.2, pharmaceutically acceptable salts thereof and combinations thereof; and a pharmaceutically acceptable carrier, in which n is 2-5, R.sub.1 is one or two naturally occurring amino acids, optionally alpha-amino acetylated with alkyl or aralkyl of 1 to 12 carbon atoms, preferably 2 to 6 carbon atoms, R.sub.2 is 1 or 2 naturally occurring amino acids, optionally alpha-carboxyl esterified or amidated with alkyl or aralkyl of 1 to 12 carbon atoms, preferably 2 to 6 carbon atoms and X is R.sub.3 -L or D-His (R.sub.4)-R.sub.5 where R.sub.3 is void or .omega.-aminoacyl with 1 to 12 carbon atoms, preferably 2 to 6 carbon atoms, R.sub.
    Type: Grant
    Filed: July 27, 1994
    Date of Patent: October 1, 1996
    Assignees: Peptide Technology Limited, King's College London
    Inventors: Jurgen Michaelis, Alan R. Hipkiss, Sianna Panagiotopoulos