Patents by Inventor Jurgen Romisch

Jurgen Romisch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the determination of antibodies against lipocortins
    Patent number: 5316915
    Abstract: The invention relates to a method for the determination of antibodies against lipocortins (annexins) in a body fluid of a species, using proteins from the lipocortin family bound to a solid phase and using a labeled bioaffinity binding partner which is directed against single classes or a plurality of classes of immunoglobulins of this species.
    Type: Grant
    Filed: December 12, 1991
    Date of Patent: May 31, 1994
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Michael Kraus, Jurgen Romisch
  • Process for removing toxins from protein solutions
    Patent number: 5136026
    Abstract: A process for removing toxins from solutions of proteins, in which an aqueous solution of a protein which contains a buffer substance, a chelating agent and a detergent is subjected to an ion exchange chromatography, is described.
    Type: Grant
    Filed: April 9, 1991
    Date of Patent: August 4, 1992
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Jurgen Romisch, Norbert Heimburger
  • Method for the purification of factor XIII by affinity chromatography
    Patent number: 5047506
    Abstract: The invention relates to a method for the purification of the a subunit of factor XIII by affinity chromatography, to a therapeutic composition containing the latter, and to the use of the therapeutic composition.Factor XIII has hitherto been purified either by methods which are technically very elaborate or else by use of toxic affinity chromatography materials. The invention has the aim of providing an improved method for the purification of the a subunit of factor XIII.Factor XIII is obtained according to the invention by a method in which the a subunit of factor XIII is reversibly bound to a matrix suitable for disulfide exchange reactions and is removed from the matrix by reaction with a reducing agent. The method according to the invention makes it possible to provide the biologically active a subunit of factor XIII in high purity.
    Type: Grant
    Filed: March 9, 1989
    Date of Patent: September 10, 1991
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Hartmut Lobermann, Jurgen Romisch, Werner Stuber