Abstract: The invention relates to a method for isolating non-embryonic stem cells from a tissue that is located in immediate vicinity of immature, developing teeth or wisdom teeth. The invention further relates to non-embryonic stem cells derived from said tissue. The method according to the invention utilises a living soft tissue residing underneath the dental papilla 12 in immediate vicinity of the apical side of a developing tooth, which is clearly distinguished from other tooth tissue, such as dental papilla 12 or follicle. The pad-like tissue 16 can only be detected in a defined, specific developmental stage in an early phase of root formation. That is, identifying and separating the pad-like tissue 16 is only possible from the appearance of the bony alveolar fundus to the end of the formation of the root of the tooth.

Abstract: The invention relates to an implant 20 comprising at least one shaft area 21 for anchoring in a bony structure and further comprising at least one opening 24 at the distal end 25 of the shaft area 21 in which the shaft area 21 has a continuous bore 23 extending from the opening 24 to at least one outlet 26 at the apical end 27, so that targeted introduction of material at least into the periapical area is possible with a stable anchoring in the bone structure even after implantation.