Abstract: An apparatus (100) detects magnetic particles in a field of view (28). The apparatus includes selection and focus magnetic field coil pairs (12, 14), drive pairs (16), and detection coils (148). A computer is configured to receive background signals with the detection coils, controls current supplied to the drive coil pair to shift the field of view in space, and reconstruct detection signals from the detection coils into an image of the field of view (28). The computer selects one or more frequency components of the detection signals and/or weighted by use of a frequency component specific signal quality factor obtained from the background signal measurements. Only the selected and/or weighted frequency components are used for reconstruction of the image.

Abstract: The present invention relates to an apparatus (100) for influencing and/or detecting magnetic particles in a field of view (28), wherein the field of view (28) comprises at least one sub field of interest covering at least a portion of an object of interest containing magnetic particles.

Abstract: The present invention relates to an apparatus (100) for detecting magnetic particles in a field of view (28), which apparatus comprises selection means, drive means, receiving means for acquiring detection signals, and reconstruction means (152) for reconstructing an image of the field of view (28) from detection signals, said detection signals including a plurality of frequency components, wherein one or more frequency components are selected and/or weighted by use of a frequency component specific signal quality factor obtained from background signal measurements and wherein only selected and/or weighted frequency components are used for reconstruction of the image.

Abstract: The present invention relates to a device for determining mechanical, particularly elastic, parameters of an examination object, comprising a) at least one arrangement for determining the spatial distribution of magnetic particles in at least one examination area of the examination object, comprising a means for generating a magnetic field with a spatial profile of the magnetic field strength such that there is produced in at least one examination area a first part-area having a low magnetic field strength and a second part-area having a higher magnetic field strength, a means for detecting signals which depend on the magnetization in the examination object, particularly in the examination area, that is influenced by a spatial change in the particles, and a means for evaluating the signals so as to obtain information about the, in particular temporally changing, spatial distribution of the magnetic particles in the examination area; and b) at least one means for generating mechanical displacements, in particu

Abstract: The invention relates to a method of determining a spatial distribution of magnetic particles in an examination zone, in which a magnetic field is generated that has a first sub-zone of lower magnetic field strength and a second sub-zone of higher magnetic field strength. The positions of the two sub-zones are changed, as a result of which the magnetization in the examination zone changes. Measured values that depend on the change in magnetization are acquired. A reference response function by means of which measured values can be determined mathematically from a spatial distribution of magnetic particles is then determined by means of at least extensive magnetic specimen distribution. Finally, the spatial distribution of magnetic particles is reconstructed from the measured values by means of the reference response function.

Abstract: The present invention relates to an apparatus (100) for influencing and/or detecting magnetic particles in a field of view (28), wherein the field of view (28) comprises at least one sub field of interest covering at least a portion of an object of interest containing magnetic particles.

Abstract: The present invention relates to an arrangement (10) for influencing and/or detecting magnetic particles in a region of action (300). The arrangement (10) comprises selection means (210) for generating a magnetic selection field (211) having a pattern in space of its magnetic field strength such that a first sub-zone (301) having a low magnetic field strength and a second sub zone (302) having a higher magnetic field strength are formed in the region of action (300), drive means (220) for changing the position in space of the two sub-zones (301, 302) in the region of action (300) by means of a magnetic drive field (221) so that the magnetization of the magnetic material changes locally, and receiving means (230) for acquiring detection signals, which detection signals depend on the magnetization in the region of action (300), which magnetization is influenced by the change in the position in space of the first and second sub-zone (301, 302).

Abstract: An arrangement for magnetic particle imaging and a method for influencing and/or detecting magnetic particles in a region of action is disclosed, which arrangement comprises: magnetic particles in a region of action, the magnetic particles being influenceable and/or detectable, selection means for generating a magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strengthare formed in the region of action, drive means for changing the position in space of the two sub-zones in the region of action by means of a magnetic drive field so that the magnetization of the magnetic particles changes locally, wherein each magneticparticle comprises a non-magnetic substrate with a layer of stainless steel.

Abstract: A radio frequency coil includes a non-cylindrical conformal surface (62, 76) that substantially conforms with a magnetic resonance subject. A plurality of conductor loops (60, 71, 72, 73, 74) are disposed in or on the non-cylindrical conformal surface. The plurality of conductor loops are configured to produce a substantially uniform Bi field in the magnetic resonance subject responsive to energizing at a Bi frequency. Optionally, a plurality of load-compensating conductor loops (90) are disposed in or on a compensatory non-cylindrical conformal surface (62) that substantially conforms with a magnetic resonance subject. The plurality of load-compensating conductor loops are configured to produce a non-uniform Bi field that compensates for a loading Bi non-uniformity caused by the magnetic resonance subject. Moreover, the coil may comprise switching means for switching the coil between a first mode of operation (e.g. a volume transmit mode) and a second mode of operation (e.g. a phased array reception mode).

Abstract: An arrangement and a method for influencing and/or detecting magnetic particles in a region of action is disclosed, which arrangement comprises: selection means for generating a magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strength are formed in the region of action, drive means for changing the position in space of the two sub-zones in the region of action by means of a magnetic drive field so that the magnetization of the magnetic particles changes locally, wherein the selection means comprise at least one permanent magnet comprising a high resistive permanent magnet material.

Abstract: A method and an arrangement for separating magnetic particles, magnetic particles and the use of magnetic particles are disclosed wherein the method comprises the steps of: —subjecting the magnetic particles to a first magnetic field such that the particle direction of easy magnetization is oriented parallel to the magnetic field vector of the first magnetic field, —subjecting the magnetic particles to a second magnetic field having an orientation rotated about an angle relative to the magnetic field vector of the first magnetic field, —applying a separating force on the magnetic particles.

Abstract: The invention relates to a method of determining a spatial distribution of magnetic particles in an examination area, in which a magnetic field is generated which has a first part-region having a relatively low magnetic field strength and a second part-region having a relatively high magnetic field strength. The position of the two part-regions is changed, as a result of which the magnetization in the examination area changes, and real measured values which depend on the change in magnetization are recorded. A dependence distribution which depends on a spatial distribution of magnetic particles is then determined such that a sum which comprises as summands a) the difference of the real measured values from fictitious measured values which are determined by applying a transfer function to the dependence distribution, and b) the product of a regularization parameter and of a regularization value which is determined by applying the regularization functional to the dependence distribution, is minimized.

Abstract: An arrangement and a method for influencing and/or detecting magnetic particles in a region of action is disclosed, which arrangement comprises:—selection means for generating a magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strength are formed in the region of action,—drive means for changing the position in space of the two sub-zones in the region of action by means of a magnetic drive field so that the magnetization of the magnetic particles changes locally,—receiving means for acquiring signals, which signals depend on the magnetization in the region of action, which magnetization is influenced by the change in the position in space of the first and second sub-zone, wherein the selection means and/or the drive means and/or the receiving means comprises at least partially a litz wire/stranded wire.

Abstract: An arrangement and a method for detecting and/or locating magnetic material, and the use of an arrangement in the examination of buildings is disclosed, which arrangement comprises: selection means for generating a magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strength are formed in the region of action, drive means for changing the position in space of the two sub-zones in the region of action by means of a magnetic drive field so that the magnetization of the magnetic material changes locally, receiving means for acquiring detection signals, which detection signals depend on the magnetization in the region of action, which magnetization is influenced by the change in the position in space of the first and second sub-zone, wherein the magnetic selection field comprises at least a time-variable field component varying at a frequency of at least about 100 Hz.

Abstract: Determination of at least one of physical, chemical and biological properties and parameters within an area of examination of an object of examination by introducing magnetic particles in at least a portion of the area of examination, generating a magnetic field with a spatial distribution of the magnetic field strength such that the area of examination includes a first sub-area with lower magnetic field strength and a second sub-area with a higher magnetic field strength, changing the spatial location of both sub-areas in the area of examination so that the magnetization of the particles changes locally, acquiring signals that depend on the magnetization in the area of examination influenced by the changing of the spatial location of both sub-areas, and evaluating the signals to obtain information about the anisotropy of the magnetic particles in the area of examination.

Abstract: The invention relates to a method of determining a spatial distribution of magnetic particles in an examination zone, in which a magnetic field is generated that has a first sub-zone of lower magnetic field strength and a second sub-zone of higher magnetic field strength. The positions of the two sub-zones are changed, as a result of which the magnetization in the examination zone changes. Measured values that depend on the change in magnetization are acquired. A reference response function by means of which measured values can be determined mathematically from a spatial distribution of magnetic particles is then determined by means of at least extensive magnetic specimen distribution. Finally, the spatial distribution of magnetic particles is reconstructed from the measured values by means of the reference response function.

Abstract: The invention relates to a method of determining a spatial distribution of magnetic particles in an examination area, in which a magnetic field is generated which has a first part-region having a relatively low magnetic field strength and a second part-region having a relatively high magnetic field strength. The position of the two part-regions is changed, as a result of which the magnetization in the examination area changes, and real measured values which depend on the change in magnetization are recorded. A dependence distribution which depends on a spatial distribution of magnetic particles is then determined such that a sum which comprises as summands a) the difference of the real measured values from fictitious measured values which are determined by applying a transfer function to the dependence distribution, and b) the product of a regularization parameter and of a regularization value which is determined by applying the regularization functional to the dependence distribution, is minimized.

Abstract: A radio frequency coil includes a non-cylindrical conformal surface (62, 76) that substantially conforms with a magnetic resonance subject. A plurality of conductor loops (60, 71, 72, 73, 74) are disposed in or on the non-cylindrical conformal surface. The plurality of conductor loops are configured to produce a substantially uniform Bi field in the magnetic resonance subject responsive to energizing at a Bi frequency. Optionally, a plurality of load-compensating conductor loops (90) are disposed in or on a compensatory non-cylindrical conformal surface (62) that substantially conforms with a magnetic resonance subject. The plurality of load-compensating conductor loops are configured to produce a non-uniform Bi field that compensates for a loading Bi non-uniformity caused by the magnetic resonance subject. Moreover, the coil may comprise switching means for switching the coil between a first mode of operation (e.g. a volume transmit mode) and a second mode of operation (e.g. a phased array reception mode).

Abstract: The invention relates to a method and an arrangement for influencing magnetic particles in a region of action. Methods and arrangements of this kind can be used to determine the spatial distribution of magnetic particles in the region of action or to heat up the magnetic particles locally. If, in addition to the magnetic particles, there is also interfering material in the region of action then this material may heat up in an unwanted way. To avoid unwanted heating-up of this kind, any interfering material that may be present is detected beforehand. If there is interfering material present, then an examination or investigation, or treatment, can be carried out with changed system parameters.

Abstract: The invention relates to a method and an arrangement for influencing magnetic particles in a region of action. Methods and arrangements of this kind can be used to determine the spatial distribution of magnetic particles in the region of action or to heat up the magnetic particles locally. If, in addition to the magnetic particles, there is also interfering material in the region of action then this material may heat up in an unwanted way. To avoid unwanted heating-up of this kind, any interfering material that may be present is detected beforehand. If there is interfering material present, then an examination or investigation, or treatment, can be carried out with changed system parameters.