Abstract: A coating for an expandable portion of a catheter comprising a lipophilic matrix and a plurality of micro-reservoirs dispersed in the lipophilic matrix is disclosed. The plurality of micro-reservoirs comprises an active agent. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided.

Abstract: A coating for an expandable portion of a catheter comprising a lipophilic matrix and a plurality of micro-reservoirs dispersed in the lipophilic matrix is disclosed. The plurality of micro-reservoirs comprises an active agent. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided.

Abstract: The invention concerns a laboratory product transport element for a laboratory transport system with an energy receiver and/or energy accumulator to provide drive power, at least one signal receiver to receive control signals, a control unit to generate drive signals as a function of at least one control signal obtained from the at least one signal receiver, movement devices for independent movement of the laboratory product transport element on a transfer path as a function of the drive signals of the control unit, in which the drive devices are driven by the drive power and at least one holder to hold a laboratory product being transported. The invention also concerns a laboratory transport system with at least one laboratory product transport element according to an embodiment of the invention and a transfer path arrangement. The invention also concerns methods for operation of laboratory transport systems according to an embodiment of the invention.

Abstract: A coating for an expandable portion of a catheter comprising a lipophilic matrix and a plurality of micro-reservoirs dispersed in the lipophilic matrix is disclosed. The plurality of micro-reservoirs comprises an active agent. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided.

Abstract: A coating for an expandable portion of a catheter comprising a hydrophobic matrix and a dispersed phase is disclosed. The dispersed phase comprises a plurality of micro-reservoirs dispersed in the hydrophobic matrix, wherein the plurality of micro-reservoirs comprises a first active agent and a first biodegradable or bioerodable polymer. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided.

Abstract: The invention concerns a laboratory product transport element for a laboratory transport system with an energy receiver and/or energy accumulator to provide drive power, at least one signal receiver to receive control signals, a control unit to generate drive signals as a function of at least one control signal obtained from the at least one signal receiver, movement devices for independent movement of the laboratory product transport element on a transfer path as a function of the drive signals of the control unit, in which the drive devices are driven by the drive power and at least one holder to hold a laboratory product being transported. The invention also concerns a laboratory transport system with at least one laboratory product transport element according to an embodiment of the invention and a transfer path arrangement. The invention also concerns methods for operation of laboratory transport systems according to an embodiment of the invention.

Abstract: The invention concerns a laboratory product transport element for a laboratory transport system with an energy receiver and/or energy accumulator to provide drive power, at least one signal receiver to receive control signals, a control unit to generate drive signals as a function of at least one control signal obtained from the at least one signal receiver, movement devices for independent movement of the laboratory product transport element on a transfer path as a function of the drive signals of the control unit, in which the drive devices are driven by the drive power and at least one holder to hold a laboratory product being transported. The invention also concerns a laboratory transport system with at least one laboratory product transport element according to an embodiment of the invention and a transfer path arrangement. The invention also concerns methods for operation of laboratory transport systems according to an embodiment of the invention.

Abstract: The invention concerns a laboratory product transport element for a laboratory transport system with an energy receiver and/or energy accumulator to provide drive power, at least one signal receiver to receive control signals, a control unit to generate drive signals as a function of at least one control signal obtained from the at least one signal receiver, movement devices for independent movement of the laboratory product transport element on a transfer path as a function of the drive signals of the control unit, in which the drive devices are driven by the drive power and at least one holder to hold a laboratory product being transported. The invention also concerns a laboratory transport system with at least one laboratory product transport element according to an embodiment of the invention and a transfer path arrangement. The invention also concerns methods for operation of laboratory transport systems according to an embodiment of the invention.

Abstract: A coating for an expandable portion of a catheter comprising a hydrophobic matrix and a dispersed phase is disclosed. The dispersed phase comprises a plurality of micro-reservoirs dispersed in the hydrophobic matrix, wherein the plurality of micro-reservoirs comprises a first active agent and a first biodegradable or bioerodable polymer. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided.

Abstract: A coating for an expandable portion of a catheter comprising a hydrophobic matrix and a dispersed phase is disclosed. The dispersed phase comprises a plurality of micro-reservoirs dispersed in the hydrophobic matrix, wherein the plurality of micro-reservoirs comprises a first active agent and a first biodegradable or bioerodable polymer. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided.

Abstract: The invention concerns a laboratory product transport element for a laboratory transport system with an energy receiver and/or energy accumulator to provide drive power, at least one signal receiver to receive control signals, a control unit to generate drive signals as a function of at least one control signal obtained from the at least one signal receiver, movement devices for independent movement of the laboratory product transport element on a transfer path as a function of the drive signals of the control unit, in which the drive devices are driven by the drive power and at least one holder to hold a laboratory product being transported. The invention also concerns a laboratory transport system with at least one laboratory product transport element according to an embodiment of the invention and a transfer path arrangement. The invention also concerns methods for operation of laboratory transport systems according to an embodiment of the invention.

Abstract: A coating for an expandable portion of a catheter comprising a hydrophobic matrix and a dispersed phase is disclosed. The dispersed phase comprises a plurality of micro-reservoirs dispersed in the hydrophobic matrix, wherein the plurality of micro-reservoirs comprises a first active agent and a first biodegradable or bioerodable polymer. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided.

Abstract: The invention concerns a laboratory product transport element for a laboratory transport system with an energy receiver and/or energy accumulator to provide drive power, at least one signal receiver to receive control signals, a control unit to generate drive signals as a function of at least one control signal obtained from the at least one signal receiver, movement devices for independent movement of the laboratory product transport element on a transfer path as a function of the drive signals of the control unit, in which the drive devices are driven by the drive power and at least one holder to hold a laboratory product being transported. The invention also concerns a laboratory transport system with at least one laboratory product transport element according to an embodiment of the invention and a transfer path arrangement. The invention also concerns methods for operation of laboratory transport systems according to an embodiment of the invention.

Abstract: A method for training a user in a medical procedure utilizes an interactive computer system with a virtual representation of at least one organ and at least one instrument. The representation of surface area parts of the virtual organ to be treated are covered with a graphical identification marker. The computer system includes a table stored in memory comprising situations arising within the medical procedure predefined through positions of the instrument(s), positions of the organ(s), the logical sequence of steps to be executed within the medical procedure, different aspect values for the graphical identification markers and assessment values for the situation. Upon interaction of the user with the organ and the instrument, graphical identification markers change their aspect according to the stored value in the table for the predefined situation and the corresponding assessment value is stored in a history log table within the computer system.

Abstract: A simulation device is disclosed for practicing manipulations of at least one elongated medical instrument, comprising a housing presenting at least one instrument input and enclosing a first motion sensor for tracking the motions of a first elongated medical instrument inserted therein. The housing encloses a bifurcating device having one input connected to the instrument input as well as at least a first and a second outputs. The bifurcating device further comprises a deflecting mechanism for guiding the first and a second elongated medical instruments from its input, respectively, through the first and second outputs, the first output being connected to the first motion sensor while the second output is connected to a second motion sensor for tracking the motions of the second elongated medical instrument. Thus, the operator's feelings are very close from those of a real medical intervention, the respective behaviour of the instruments being substantially identical.

Abstract: The present invention relates to a simulation device (2), for practicing manipulations of at least one elongated medical instrument (101, 102), comprising a housing (11) presenting at least one instrument input (10) and enclosing a first motion sensor (18) for tracking the motions of a first elongated medical instrument (101) inserted therein. The housing encloses a bifurcating device (14, 140) having one input (13, 142) connected to the instrument input as well as at least a first and a second outputs (23, 24), the bifurcating device further comprising a deflecting mechanism (15, 141) for guiding the first and a second elongated medical instruments (101, 102) from its input, respectively, through the first and second outputs, the first output being connected to the first motion sensor while the second output is connected to a second motion sensor for tracking the motions of the second elongated medical instrument.

Abstract: Devices are provided for determining the longitudinal and angular positions of a rotationally symmetrical apparatus, when guided inside an element surrounding the same is provided. In one implementation, a device is provided that comprises a bead held in motion-transmitting contact with the apparatus, and includes an imaging optical navigation sensor that measures the motion of the bead by comparing successive images of its outer surface. The bead may be made of a paramagnetic material. Further, the device may include a magnetic device for applying a magnetic force onto the bead to secure its contact with the apparatus. Additional features of the device may be used to identify the insertion and withdrawal of the apparatus in the device as they cause a displacement of the bead, therefore allowing the determination of the absolute position of the apparatus.

Abstract: An actuator for an elongated object may include one or two electromagnetically-activated braking mechanisms to provide haptic sensations in conjunction with a device that tracks a rotationally symmetric instrument manipulated by a user. A contact-free motion sensor may provide information about the longitudinal movement and about the rotational movement of the instrument, and a control unit may receive movement information from the motion sensor and may be connected with the electromagnetically-activated braking mechanisms. Each braking mechanism may include a first surface and a second surface, the second one at least being movable in the direction of the first one to pinch or release the instrument as a function of the motion information provided by the motion sensor. In the case of two braking mechanisms a braking force may be applied on the guided instrument for both degrees of freedom independently.

Abstract: A method for training a user in a medical procedure utilizes an interactive computer system with a virtual representation of at least one organ and at least one instrument. The representation of surface area parts of the virtual organ to be treated are covered with a graphical identification marker. The computer system includes a table stored in memory comprising situations arising within the medical procedure predefined through positions of the instrument(s), positions of the organ(s), the logical sequence of steps to be executed within the medical procedure, different aspect values for the graphical identification markers and assessment values for the situation. Upon interaction of the user with the at least one organ and the at least one instrument, one or more graphical identification markers change their aspect according to the stored value in the table for the predefined situation and the corresponding assessment value is stored in a history log table within the computer system.

Abstract: A device for determining the longitudinal and angular position of a rotationally symmetrical apparatus when guided inside a longitudinal element surrounding the same, including an imaging optical navigation sensor that measures the motion of the underlying surface by comparing successive images, and translates this image translation into a measurement of the longitudinal and rotational motion of the instrument. Features of the captured image are used to identify the insertion or withdrawal of the instrument, and to identify specific areas of the moving surface passing underneath the sensor, therefore allowing to establish the absolute position of the instrument, or to identify which instrument was inserted or in what cavity a tracking instrument was inserted. The device comprises a light source and a light detector. Light emitted by said light source is directed onto a surface of the rotationally symmetrical apparatus.