Abstract: Provided herein are methods of separating host cell lipases from a production protein in chromatographic processes and methods of improving polysorbate-80 stability in a production protein formulation by separating host cell lipases from the production protein using chromatographic processes. Also provided herein are compositions comprising antibodies or antigen binding fragments thereof that bind to cytotoxic T lymphocyte associated antigen 4 (CTLA4). In another aspect, such compositions further comprise a reduced level of host cell proteins and/or increased level of polysorbate-80 (PS-80) stability.

Abstract: A discrete VRM card includes a first VRM controller and a second VRM controller. The discrete VRM card also includes a first primary power stage, a second primary power stage, and an adaptable spare stage. The discrete VRM card includes a first switch and a second switch. Closing the first switch connects the adaptable spare converter with an output of the first primary power stage. Closing the second switch connects the adaptable spare converter an output of the second primary power stage.

Abstract: Provided herein are methods of separating host cell lipases from a production protein in chromatographic processes and methods of improving polysorbate-80 stability in a production protein formulation by separating host cell lipases from the production protein using chromatographic processes. Also provided are pharmaceutical compositions comprising less than 1 ppm of a host cell lipase.

Abstract: Provided are methods and systems for providing personalized communications. An exemplary method can comprise determining an interest level in contributing to a media message for a recipient. The method can comprise selecting, based on the interest level, a plurality of contributors from a network of members associated with a recipient. The method can also comprise receiving at least two messages in one or more formats from the plurality of contributors. The method can further comprise combining the at least two messages into a media message. The method can comprise providing the media message to a recipient.

Abstract: Provided are methods and systems for providing personalized communications. An exemplary method can comprise determining an interest level in contributing to a media message for a recipient. The method can comprise selecting, based on the interest level, a plurality of contributors from a network of members associated with a recipient. The method can also comprise receiving at least two messages in one or more formats from the plurality of contributors. The method can further comprise combining the at least two messages into a media message. The method can comprise providing the media message to a recipient.