Abstract: A dialysis system includes a dialysis instrument including a blood pump, a dialysate inlet pump, a dialysate outlet pump, and at least one fluid velocity sensor, each sensor including an emitter and a receiver, a dialyzer arranged (i) to receive blood pumped by the blood pump, (ii) to receive fresh dialysate pumped by the dialysate inlet pump and (iii) such that used dialysate is pumped from the dialyzer by the dialysate outlet pump, and a disposable cassette including a to-dialyzer dialysate pathway carrying dialysate pumped by the dialysate inlet pump and a from-dialyzer dialysate pathway carrying used dialysate pumped by the dialysate outlet pump, wherein at least one of the to-dialyzer dialysate pathway or the from-dialyzer dialysate pathway includes at least one sensing area so positioned and arranged such that when the disposable cassette is mounted to the instrument, the sensing area is coupled operably with both the emitter and the receiver of the at least one fluid velocity sensor.

Abstract: An air purging method includes: (a) detecting a low fluid level in a blood circuit indicating a high amount of air in the blood circuit; (b) stopping a blood pump; (c) closing a venous patient line; (d) opening a blood circuit air vent valve and a drain valve; and (e) running the blood pump to meter air through the air vent valve and the drain valve to a drain.

Abstract: An air purging method includes: (a) detecting a low fluid level in a blood circuit indicating a high amount of air in the blood circuit; (b) stopping a blood pump; (c) closing a venous patient line; (d) opening a blood circuit air vent valve and a drain valve; and (e) running the blood pump to meter air through the air vent valve and the drain valve to a drain.

Abstract: In general, multiple embodiments of a catheter/fistula needle to bloodline connection assurance device, which secures and strengthens a connection between an extension tube end of a catheter or fistula needle and a bloodline are provided. A first embodiment of the assurance device is configured to be compatible with any industrial catheter/fistula needle female luer connector and is specifically configured for use with a bloodline connector having locking clips which are biased slightly outwardly from the bloodline connector. The first embodiment of the assurance device is cylindrical and includes clamshell halves that open rotatably about at least one hinge. The first embodiment of the assurance device includes an upper, threaded portion and a lower housing portion. The interior wall of the upper portion defines a plurality of barbs configured to engage with distal or moveable ends of the locking clips.

Abstract: An air purging method includes: (a) detecting a low fluid level in a blood circuit indicating a high amount of air in the blood circuit; (b) stopping a blood pump; (c) closing a venous patient line; (d) opening a blood circuit air vent valve and a drain valve; and (e) running the blood pump to meter air through the air vent valve and the drain valve to a drain.

Abstract: An air purging method includes: (a) detecting a low fluid level in a blood circuit indicating a high amount of air in the blood circuit; (b) stopping a blood pump; (c) closing a venous patient line; (d) opening a blood circuit air vent valve and a drain valve; and (e) running the blood pump to meter air through the air vent valve and the drain valve to a drain.

Abstract: An access disconnect sensor for a patient undergoing extracorporeal blood processing includes an electrochemical fuel cell or sensor to detect blood leakage. The fuel cell includes circuitry for oxidizing glucose in the blood. The sensor also includes a transmitter to send a signal to a remote receiver that the sensor indicates the presence of blood. The circuitry may include a battery or may use electricity generated by the sensor to send a signal indicating a leak of blood or disconnection of the access needle.

Abstract: Systems and methods for removing hydrogen peroxide from water purification systems are provided. In a general embodiment, the present disclosure provides a water purification system including a water treatment unit, an electrodeionization unit and a hydrogen peroxide decomposition catalyst in fluid connection with the electrodeionization unit. The water purification system can be fluidly connected to a renal treatment system.

Abstract: A medical fluid delivery system includes a fluid disposable configured to hold and transport a medical fluid and an air separation chamber in fluid communication with the fluid disposable. The air separation chamber includes at least one fluid baffle floating within the air separation chamber and configured to separate air from medical fluid traveling through the chamber.

Abstract: A dialysis system includes a dialysis fluid disposable configured to hold and transport a dialysis fluid; an air separation chamber in fluid communication with the dialysis fluid disposable; and a dialysis instrument operable to pump dialysis fluid through the dialysis fluid disposable, the instrument including a vibrator configured to vibrate the air separation chamber to separate air from the dialysis fluid traveling through the chamber.

Abstract: A medical fluid delivery system includes a fluid disposable configured to hold and transport a medical fluid and an air separation chamber in fluid communication with the fluid disposable. The air separation chamber includes at least one fluid baffle floating within the air separation chamber and configured to separate air from medical fluid traveling through the chamber.

Abstract: A dialysis system includes a dialysis fluid disposable configured to hold and transport a dialysis fluid; an air separation chamber in fluid communication with the dialysis fluid disposable; and a dialysis instrument operable to pump dialysis fluid through the dialysis fluid disposable, the instrument including a vibrator configured to vibrate the air separation chamber to separate air from the dialysis fluid traveling through the chamber.

Abstract: A dialysis fluid cassette includes a rigid portion defining first and second valve chambers, the rigid portion further defining an air separation chamber in fluid communication with the first and second valve chambers, the air separation chamber including a baffle and structured such that when the cassette is placed in a dialysis instrument, (i) the baffle extends upwardly from a bottom of the air separation chamber and (ii) first and second openings to the air separation chamber, communicating fluidly and respectively with the first and second valve chambers, are located near the bottom of the air separation chamber, such that the dialysis fluid is forced up one side of the baffle and down the other side of the baffle when flowing through the air separation chamber.

Abstract: In general, multiple embodiments of a catheter/fistula needle to bloodline connection assurance device, which secures and strengthens a connection between an extension tube end of a catheter or fistula needle and a bloodline are provided. A first embodiment of the assurance device is configured to be compatible with any industrial catheter/fistula needle female luer connector and is specifically configured for use with a bloodline connector having locking clips which are biased slightly outwardly from the bloodline connector. The first embodiment of the assurance device is cylindrical and includes clamshell halves that open rotatably about at least one hinge. The first embodiment of the assurance device includes an upper, threaded portion and a lower housing portion. The interior wall of the upper portion defines a plurality of barbs configured to engage with distal or moveable ends of the locking clips.

Abstract: A system for monitoring water quality for dialysis, dialysis fluids, and body fluids treated by dialysis fluids, is disclosed. The system uses microelectromechanical systems (MEMS) sensors for detecting impurities in input water or dialysis fluid, and in the prepared dialysate. These sensors may also be used to monitor and check the blood of the patient being treated. These sensors include ion-selective sensors, for ions such as ammonium or calcium, and also include amperometric array sensors, suitable for ions from chlorine or chloramines, e.g., chloride. These sensors assist in the monitoring of water supplies from a city water main or well. The sensors may be used in conjunction with systems for preparing dialysate solutions from water for use at home or elsewhere.

Abstract: A dialysis system includes a dialysis machine with a variable fluid demand including at least a lower demand and a higher demand. A fluid source is in fluid communication with the dialysis machine and provides fluid to the dialysis machine at a fluid flow rate. A flow regulation device includes a fluid inlet in fluid communication with the fluid source and a fluid outlet in fluid communication with the dialysis machine. The flow regulation device is operable to expand and contract to provide a variable internal volume. The flow regulation device expands when the dialysis machine has the lower demand and contracts when the dialysis machine has the higher demand.

Abstract: An access disconnect sensor for a patient undergoing extracorporeal blood processing includes an electrochemical fuel cell or sensor to detect blood leakage. The fuel cell includes circuitry for oxidizing glucose in the blood. The sensor also includes a transmitter to send a signal to a remote receiver that the sensor indicates the presence of blood. The circuitry may include a battery or may use electricity generated by the sensor to send a signal indicating a leak of blood or disconnection of the access needle.

Abstract: A dialysis fluid cassette includes a rigid portion defining first and second valve chambers, the rigid portion further defining an air separation chamber in fluid communication with the first and second valve chambers, the air separation chamber including a baffle and structured such that when the cassette is placed in a dialysis instrument, (i) the baffle extends upwardly from a bottom of the air separation chamber and (ii) first and second openings to the air separation chamber, communicating fluidly and respectively with the first and second valve chambers, are located near the bottom of the air separation chamber, such that the dialysis fluid is forced up one side of the baffle and down the other side of the baffle when flowing through the air separation chamber.

Abstract: An air purging method includes: (a) detecting a low fluid level in a blood circuit indicating a high amount of air in the blood circuit; (b) stopping a blood pump; (c) closing a venous patient line; (d) opening a blood circuit air vent valve and a drain valve; and (e) running the blood pump to meter air through the air vent valve and the drain valve to a drain.

Abstract: An access disconnect sensor for a patient undergoing extracorporeal blood processing includes an electrochemical fuel cell or sensor to detect blood leakage. The fuel cell includes circuitry for oxidizing glucose in the blood. The sensor also includes a transmitter to send a signal to a remote receiver that the sensor indicates the presence of blood. The circuitry may include a battery or may use electricity generated by the sensor to send a signal indicating a leak of blood or disconnection of the access needle.