Patents by Inventor Justin Cisar

Justin Cisar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FLUORINATED QUINOLINE, QUINOXALINE AND BENZO[B][1,4]OXAZINE DERIVATIVES AS DIHYDROOROTATE DEHYDROGENASE (DHODH) INHIBITORS FOR THE TREATMENT OF CANCER, AUTOIMMUNE AND INFLAMMATORY DISEASES
    Publication number: 20240166622
    Abstract: Disclosed are compounds, compositions, and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula (I) as follows: wherein X, Y, R1a, R1b, Z1, Z2, Z3, R2, and R3, are defined herein.
    Type: Application
    Filed: October 30, 2020
    Publication date: May 23, 2024
    Inventors: Justin Cisar, Scott Kuduk, Aihua Wang, Zhuming Zhang, Chao-yuan Wang
  • BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS
    Publication number: 20240158414
    Abstract: Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula I as follows: wherein R1, R2, R3, and Q are defined herein.
    Type: Application
    Filed: October 9, 2020
    Publication date: May 16, 2024
    Inventors: Justin Cisar, Scott Kuduk, Lindsey DeRatt, Yvan Rene Ferdinand Simonnet
  • FLUORINATED QUINOLINE AND QUINOXALINE DERIVATIVES AS DIHYDROOROTATE DEHYDROGENASE (DHODH) INHIBITORS FOR THE TREATMENT OF CANCER, AUTOIMMUNE AND INFLAMMATORY DISEASES
    Publication number: 20230037448
    Abstract: Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula (I) as follows: wherein R1a, R1b, R2, and R3, are defined herein.
    Type: Application
    Filed: October 30, 2020
    Publication date: February 9, 2023
    Inventors: Justin Cisar, Colleen Keohane, Scott Kuduk
  • DIHYDROOROTATE DEHYDROGENASE INHIBITORS
    Publication number: 20220089568
    Abstract: Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula (I) as follows: wherein R1a, R1b, R2, and R3, are defined herein.
    Type: Application
    Filed: January 10, 2020
    Publication date: March 24, 2022
    Inventors: Justin Cisar, Scott Kuduk, Chao-yuan Wang, Yvan Rene Ferdinand Simonnet, Colleen Elizabeth Keohane, Edgar Jacoby
  • DIHYDROOROTATE DEHYDROGENASE INHIBITORS
    Publication number: 20220081422
    Abstract: Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Embodiments of such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5a, R5b, X and Y, are defined herein.
    Type: Application
    Filed: February 6, 2020
    Publication date: March 17, 2022
    Inventors: Justin Cisar, Scott Kuduk, Zhuming Zhang, Aihua Wang, Yvan Simonnet