Patents by Inventor Justin E. Silpe

Justin E. Silpe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260206778
    Abstract: Described herein, are compositions and methods for preserving human milk, preventing rancidity of human milk, extending shelf life of human milk, and maintaining the nutritional properties of human milk. Specifically, the present disclosure provides, among other things, devices for storing preserved human milk and methods and compositions for preserving the same.
    Type: Application
    Filed: December 23, 2025
    Publication date: July 23, 2026
    Applicant: The Trustees of Princeton University
    Inventors: Justin E. Silpe, Bonnie L. Bassler
  • Patent number: 12507703
    Abstract: Described herein, are compositions and methods for preserving human milk, preventing rancidity of human milk, extending shelf life of human milk, and maintaining the nutritional properties of human milk. Specifically, the present disclosure provides, among other things, devices for storing preserved human milk and methods and compositions for preserving the same.
    Type: Grant
    Filed: January 17, 2025
    Date of Patent: December 30, 2025
    Assignee: The Trustees of Princeton University
    Inventors: Justin E. Silpe, Bonnie L. Bassler
  • Publication number: 20250169516
    Abstract: Described herein, are compositions and methods for preserving human milk, preventing rancidity of human milk, extending shelf life of human milk, and maintaining the nutritional properties of human milk. Specifically, the present disclosure provides, among other things, devices for storing preserved human milk and methods and compositions for preserving the same.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 29, 2025
    Applicant: The Trustees of Princeton University
    Inventors: Justin E. Silpe, Bonnie L. Bassler
  • Patent number: 12239142
    Abstract: Described herein, are compositions and methods for preserving human milk, preventing rancidity of human milk, extending shelf life of human milk, and maintaining the nutritional properties of human milk. Specifically, the present disclosure provides, among other things, devices for storing preserved human milk and methods and compositions for preserving the same.
    Type: Grant
    Filed: February 14, 2024
    Date of Patent: March 4, 2025
    Assignee: The Trustees of Princeton University
    Inventors: Justin E. Silpe, Bonnie L. Bassler
  • Patent number: 12209256
    Abstract: Recombinant phages that infect and kill bacterial hosts in response to user-defined inputs are provided. The components that encode the user-defined inputs can be combined, such that multiple inputs are maintained on a single recombinant phage, enabling precise control over the targeting strategy. The phages can be engineered to kill a specific bacterial species or multiple species simultaneously. Recombinant phages can also be engineered to harbor fluorescent and bioluminescent reporter genes that enable them to be used for tracking, detection, and in biosensing applications. Recombinant phages can also be used to lyse bacterial cells that produce recombinant proteins, as a rapid method to enable extraction and high-level purification of potentially valuable and/or industrially important proteins. Systems are provided that can be used to control the activity of a protein of interest, by taking advantage of an interaction between Qtip and a phage repressor protein.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: January 28, 2025
    Assignee: THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Justin E. Silpe, Bonnie L. Bassler
  • Publication number: 20240268402
    Abstract: Described herein, are compositions and methods for preserving human milk, preventing rancidity of human milk, extending shelf life of human milk, and maintaining the nutritional properties of human milk. Specifically, the present disclosure provides, among other things, devices for storing preserved human milk and methods and compositions for preserving the same.
    Type: Application
    Filed: February 14, 2024
    Publication date: August 15, 2024
    Applicant: The Trustees of Princeton University
    Inventors: Justin E. Silpe, Bonnie L. Bassler
  • Publication number: 20220010284
    Abstract: Disclosed are recombinant phages that infect and kill bacterial hosts in response to user-defined inputs. The components that encode the user-defined inputs can be combined, such that multiple inputs are maintained on a single recombinant phage, enabling precise control over the targeting strategy. The phages can be engineered to kill a specific bacterial species or multiple species simultaneously. Recombinant phages can also be engineered to harbor fluorescent and bioluminescent reporter genes that enable them to be used for tracking, detection, and in biosensing applications. Recombinant phages can also be used to lyse bacterial cells that produce recombinant proteins, as a rapid method to enable extraction and high-level purification of potentially valuable and/or industrially important proteins.
    Type: Application
    Filed: October 31, 2019
    Publication date: January 13, 2022
    Applicant: The Trustees of Princeton University
    Inventors: Justin E. Silpe, Bonnie L. Bassler
  • Patent number: 9068695
    Abstract: Magnetorheological (MR) antibubbles are used for fluid delivery. A method of transporting a substance in a fluid in accordance with the invention comprising the steps of forming an antibubble in the fluid, the antibubble containing the substance to be transported and magnetic or magnetizable particles, and guiding the antibubble through the fluid with a magnet. The particles are ferromagnetic, paramagnetic or diamagnetic, and the magnet is a permanent magnet or an electromagnet. The substance to be transported may include a reactant associated with a catalytic mechanism; a pigment; or a lubricant. The delivery system may include a substance or magnetic particles which are fluorescent.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: June 30, 2015
    Assignee: SMRT Delivery LLC
    Inventor: Justin E. Silpe
  • Publication number: 20130327409
    Abstract: Magnetorheological (MR) antibubbles are used for fluid delivery. A method of transporting a substance in a fluid in accordance with the invention comprising the steps of forming an antibubble in the fluid, the antibubble containing the substance to be transported and magnetic or magnetizable particles, and guiding the antibubble through the fluid with a magnet. The particles are ferromagnetic, paramagnetic or diamagnetic, and the magnet is a permanent magnet or an electromagnet. The substance to be transported may include a reactant associated with a catalytic mechanism; a pigment; or a lubricant. The delivery system may include a substance or magnetic particles which are fluorescent.
    Type: Application
    Filed: August 23, 2012
    Publication date: December 12, 2013
    Inventor: Justin E. Silpe