Abstract: Autonomic threat detection is performed by collecting traffic samples of traffic patterns associated with a networked device having a device resident validation module. A threat analysis system is used to recognize a pattern of traffic indicative of a compromised device based at least in part upon the traffic samples. If the samples indicate a compromised device, the device is quarantined and a security check is performed on the device. The security check may include requesting data from the corresponding device resident validation module to determine if the device is compromised, analyzing data from the device resident validation module of the quarantined device and taking an action based upon analysis of the data. At least one of the data from the device resident validation module of the quarantined device or the traffic samples is utilized to autonomically train the threat analysis system to identify compromised devices.