Patents by Inventor Justin M. Lopchuk

Justin M. Lopchuk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MERGED SCAFFOLD TAF1 INHIBITORS
    Publication number: 20240002378
    Abstract: Disclosed are inhibitors for TAF1. Methods of using the disclosed compounds to treat cancer are also disclosed.
    Type: Application
    Filed: November 30, 2021
    Publication date: January 4, 2024
    Inventors: Justin M. LOPCHUK, Ernst SCHONBRUNN, Zachary SHULTZ, Md Rezaul KARIM, Jiandong CHEN
  • PROCESS FOR THE PREPARATION OF HETEROARYL-SUBSTITUTED SULFUR(VI) COMPOUNDS
    Publication number: 20230399302
    Abstract: The present disclosure provides processes for the synthesis of organic compounds, in particular processes for the synthesis of heteroaryl-substituted sulfur(VI) compounds by nucleophilic aromatic substitution.
    Type: Application
    Filed: October 29, 2021
    Publication date: December 14, 2023
    Inventors: Justin M. Lopchuk, Zachary P. SHULTZ, Thomas SCATTOLIN
  • PROCESSES AND COMPOUNDS FOR THE DECARBOXYLATIVE AMINATION OF REDOX-ACTIVE ESTERS WITH DIAZIRINES
    Publication number: 20220274930
    Abstract: The invention described herein relates generally to processes for the synthesis of amine-containing organic compounds. More specifically, described herein relates to processes for the decarboxylative amination of redox-active esters with diazirines and the products formed thereof. Compounds for use in the above processes are also described.
    Type: Application
    Filed: June 15, 2020
    Publication date: September 1, 2022
    Inventors: Justin M. LOPCHUK, Preeti P. CHANDRACHUD
  • Compositions and methods for treating cancer
    Patent number: 8975274
    Abstract: The present invention is bis-acridine or bis-quinoline intercalators having a modified bis(4-aminophenyl)ether tether to improve activity, selectivity, solubility and bioavailability of the antitumor compound.
    Type: Grant
    Filed: September 18, 2012
    Date of Patent: March 10, 2015
    Assignee: Trustees of Dartmouth College
    Inventors: Gordon W. Gribble, Justin M. Lopchuk
  • COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20140228392
    Abstract: The present invention is bis-acridine or bis-quinoline intercalators having a modified bis(4-aminophenyl)ether tether to improve activity, selectivity, solubility and bioavailability of the antitumor compound.
    Type: Application
    Filed: September 18, 2012
    Publication date: August 14, 2014
    Inventors: Gordon W. Gribble, Justin M. Lopchuk
  • Compositions and methods for treating cancer
    Patent number: 8530496
    Abstract: The present invention is bis-acridine or bis-quinoline intercalators having a modified bis(4-aminophenyl)ether tether to improve activity, selectivity, solubility and bioavailability of the antitumor compound.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: September 10, 2013
    Assignee: Trustees of Dartmouth College
    Inventors: Gordon W. Gribble, Justin M. Lopchuk
  • Compositions and Methods for Treating Cancer
    Publication number: 20120022097
    Abstract: The present invention is bis-acridine or bis-quinoline intercalators having a modified bis(4-aminophenyl)ether tether to improve activity, selectivity, solubility and bioavailability of the antitumor compound.
    Type: Application
    Filed: September 20, 2011
    Publication date: January 26, 2012
    Applicant: Trustees of Dartmouth College
    Inventors: Gordon W. Gribble, Justin M. Lopchuk