Patents by Inventor Justin M. Saul

Justin M. Saul has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11090410
    Abstract: Provided herein are scaffolds and methods useful to promote the formation of functional clusters on a tissue, for example, motor endplates (MEPs) or a component thereof on skeletal muscle cells or tissue, as well as the use of scaffolds so produced for repairing a tissue injury or defect.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: August 17, 2021
    Assignee: WAKE FOREST UNIVERSITY HEALTH SCIENCES
    Inventors: George J. Christ, Justin M. Saul, John B. Scott, Benjamin T. Corona, Benjamin S. Harrison, Catherine Ward
  • Patent number: 10434213
    Abstract: Provided herein are keratin compositions (e.g., keratin gels, scaffolds, particulates, and the like) including a compound of interest, useful for release and/or delivery of the compound of interest (e.g., in vivo or in vitro). In some embodiments, the composition is a composition formulated for controlled release of the compound of interest.
    Type: Grant
    Filed: March 7, 2011
    Date of Patent: October 8, 2019
    Assignee: Wake Forest University Health Sciences
    Inventors: Mark E. Van Dyke, Justin M. Saul, Thomas L. Smith, Roche de Guzman
  • Patent number: 10398739
    Abstract: A composition comprising microcapsules, the microcapsules containing both live mammalian ovarian granulosa cells and live mammalian ovarian theca cells, is described. In some embodiments, the granulosa cells and the theca cells are contained in separate microcapsules in the composition; in some embodiments, the granulosa cells and the theca cells are contained together in the same microcapsules in the composition. The composition is can be used for estrogen, and optionally also progesterone, delivery, and hence is preferably free or essentially free of oocytes. Methods of using the same and pharmaceutical formulations containing the same are also described.
    Type: Grant
    Filed: September 2, 2014
    Date of Patent: September 3, 2019
    Assignee: Wake Forest University Health Sciences
    Inventors: Emmanuel C. Opara, James J. Yoo, Justin M. Saul, Sittadjody Sivanandane, Anthony Atala
  • Publication number: 20180236131
    Abstract: Provided herein are scaffolds and methods useful to promote the formation of functional clusters on a tissue, for example, motor endplates (MEPs) or a component thereof on skeletal muscle cells or tissue, as well as the use of scaffolds so produced for repairing a tissue injury or defect.
    Type: Application
    Filed: April 18, 2018
    Publication date: August 23, 2018
    Inventors: George J. Christ, Justin M. Saul, John B. Scott, Benjamin T. Corona, Benjamin S. Harrison, Catherine Ward
  • Patent number: 9968705
    Abstract: Provided herein are scaffolds and methods useful to promote the formation of functional clusters on a tissue, for example, motor endplates (MEPs) or a component thereof on skeletal muscle cells or tissue, as well as the use of scaffolds so produced for repairing a tissue injury or defect.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: May 15, 2018
    Assignee: Wake Forest University Health Sciences
    Inventors: George J. Christ, Justin M. Saul, John B Scott, Benjamin T. Corona, Benjamin S. Harrison, Catherine Ward
  • Patent number: 9763986
    Abstract: A composition comprising microcapsules, the microcapsules containing both live mammalian ovarian granulosa cells and live mammalian ovarian theca cells, is described. In some embodiments, the granulosa cells and the theca cells are contained in separate microcapsules in the composition; in some embodiments, the granulosa cells and the theca cells are contained together in the same microcapsules in the composition The composition is can be used for estrogen, and optionally also progesterone, delivery, and hence is preferably free or essentially free of oocytes. Methods of using the same and pharmaceutical formulations containing the same are also described.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: September 19, 2017
    Assignee: Wake Forest University Health Sciences
    Inventors: Emmanuel Opara, James J. Yoo, Justin M. Saul, Sittadjody Sivanandane, Anthony Atala
  • Publication number: 20160206665
    Abstract: A composition comprising microcapsules, the microcapsules containing both live mammalian ovarian granulosa cells and live mammalian ovarian theca cells, is described. In some embodiments, the granulosa cells and the theca cells are contained in separate microcapsules in the composition; in some embodiments, the granulosa cells and the theca cells are contained together in the same microcapsules in the composition The composition is can be used for estrogen, and optionally also progesterone, delivery, and hence is preferably free or essentially free of oocytes. Methods of using the same and pharmaceutical formulations containing the same are also described.
    Type: Application
    Filed: February 3, 2016
    Publication date: July 21, 2016
    Inventors: Emmanuel Opara, James J. Yoo, Justin M. Saul, Sittadjody Sivanandane, Anthony Atala
  • Publication number: 20160166620
    Abstract: A composition comprising microcapsules, the microcapsules containing both live mammalian ovarian granulosa cells and live mammalian ovarian theca cells, is described. In some embodiments, the granulosa cells and the theca cells are contained in separate microcapsules in the composition; in some embodiments, the granulosa cells and the theca cells are contained together in the same microcapsules in the composition. The composition is can be used for estrogen, and optionally also progesterone, delivery, and hence is preferably free or essentially free of oocytes. Methods of using the same and pharmaceutical formulations containing the same are also described.
    Type: Application
    Filed: September 2, 2014
    Publication date: June 16, 2016
    Inventors: Emmanuel C. Opara, James J. Yoo, Justin M. Saul, Sittadjody Sivanandane, Anthony Atala
  • Patent number: 9283251
    Abstract: A composition comprising microcapsules, the microcapsules containing both live mammalian ovarian granulosa cells and live mammalian ovarian theca cells, is described. In some embodiments, the granulosa cells and the theca cells are contained in separate microcapsules in the composition; in some embodiments, the granulosa cells and the theca cells are contained together in the same microcapsules in the composition The composition is can be used for estrogen, and optionally also progesterone, delivery, and hence is preferably free or essentially free of oocytes. Methods of using the same and pharmaceutical formulations containing the same are also described.
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: March 15, 2016
    Assignee: Wake Forest University Health Sciences
    Inventors: Emmanuel Opara, James J. Yoo, Justin M. Saul, Sittadjody Sivanandane, Anthony Atala
  • Publication number: 20140234388
    Abstract: Provided herein are scaffolds and methods useful to promote the formation of functional clusters on a tissue, for example, motor endplates (MEPs) or a component thereof on skeletal muscle cells or tissue, as well as the use of scaffolds so produced for repairing a tissue injury or defect.
    Type: Application
    Filed: September 28, 2012
    Publication date: August 21, 2014
    Applicant: Wake Forest University Health Sciences
    Inventors: George J. Christ, Justin M. Saul, John B Scott, Benjamin T. Corona, Benjamin S. Harrison, Catherine Ward
  • Publication number: 20140127308
    Abstract: A composition comprising microcapsules, the microcapsules containing both live mammalian ovarian granulosa cells and live mammalian ovarian theca cells, is described. In some embodiments, the granulosa cells and the theca cells are contained in separate microcapsules in the composition; in some embodiments, the granulosa cells and the theca cells are contained together in the same microcapsules in the composition The composition is can be used for estrogen, and optionally also progesterone, delivery, and hence is preferably free or essentially free of oocytes. Methods of using the same and pharmaceutical formulations containing the same are also described.
    Type: Application
    Filed: February 21, 2012
    Publication date: May 8, 2014
    Applicant: Wake Forest University Health Sciences
    Inventors: Emmanuel Opara, James J. Yoo, Justin M. Saul, Sittadjody Sivanandane, Anthony Atala
  • Publication number: 20110217356
    Abstract: Provided herein are keratin compositions (e.g., keratin gels, scaffolds, particulates, and the like) including a compound of interest, useful for release and/or delivery of the compound of interest (e.g., in vivo or in vitro). In some embodiments, the composition is a composition formulated for controlled release of the compound of interest.
    Type: Application
    Filed: March 7, 2011
    Publication date: September 8, 2011
    Inventors: Mark E. Van Dyke, Justin M. Saul, Thomas L. Smith, Roche de Guzman