Patents by Inventor Justin Maxhimer

Justin Maxhimer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Radioprotectants targeting thrombospondin-1 and CD47
    Patent number: 8951527
    Abstract: Described herein is the discovery that cell and tissue survival can be dramatically increased following radiation exposure through inhibition of the interaction between TSP-1 and CD47. This effect is shown using antisense molecules, peptides, and antibodies, which can now be used as radioprotectant agents. These agents find application in minimizing, reducing and/or preventing tissue damage following intentional and accidental radiation exposure, as well as increasing the therapeutic efficacy of radiation therapies by protecting non-target tissue from incidental radiation damage and by increasing tumor ablation following radiation treatment.
    Type: Grant
    Filed: August 5, 2009
    Date of Patent: February 10, 2015
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Jeffrey S. Isenberg, David D. Roberts, Justin Maxhimer
  • RADIOPROTECTANTS TARGETING THROMBOSPONDIN-1 AND CD47
    Publication number: 20110135641
    Abstract: Described herein is the discovery that cell and tissue survival can be dramatically increased following radiation exposure through inhibition of the interaction between TSP-1 and CD47. This effect is shown using antisense molecules, peptides, and antibodies, which can now be used as radioprotectant agents. These agents find application in minimizing, reducing and/or preventing tissue damage following intentional and accidental radiation exposure, as well as increasing the therapeutic efficacy of radiation therapies by protecting non-target tissue from incidental radiation damage and by increasing tumor ablation following radiation treatment.
    Type: Application
    Filed: August 5, 2009
    Publication date: June 9, 2011
    Inventors: Jeffrey S. Isenberg, David D. Roberts, Justin Maxhimer