Patents by Inventor Justin Noehre

Justin Noehre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptidomimetic macrocycles
    Patent number: 10300109
    Abstract: Disclosed are peptidomimetic macrocycles comprising a helix, such as an alpha helix, and methods of using such macrocycles for the treatment of disease such as cancer. In other aspects, the peptidomimetic macrocycle comprises an ?,?-disubstituted amino acid, or may comprise a crosslinker linking the ?-positions of at least two amino acids or at least one of said two amino acids may be an ?,?-disubstituted amino acid. Further included is the targeting of components of the Wnt signaling pathway such as the Tcf4-/3-catenin complex.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: May 28, 2019
    Assignee: AILERON THERAPEUTICS, INC.
    Inventors: Huw M. Nash, Rosana Kapeller-Libermann, Jia-Wen Han, Tomi K. Sawyer, Justin Noehre, Noriyuki Kawahata
  • PEPTIDOMIMETIC MACROCYCLES
    Publication number: 20130072439
    Abstract: Disclosed are peptidomimetic macrocycles comprising a helix, such as an alpha helix, and methods of using such macrocycles for the treatment of disease such as cancer. In other aspects, the peptidomimetic macrocycle comprises an a,a-disubstituted amino acid, or may comprise a crosslinker linking the a-positions of at least two amino acids or at least one of said two amino acids may be an a,a-disubstituted amino acid. Further included is the targeting of components of the Wnt signaling pathway such as the Tcf4-/3-catenin complex.
    Type: Application
    Filed: September 22, 2010
    Publication date: March 21, 2013
    Inventors: Huw M. Nash, Rosana Kapeller-Libermann, Jia-wen Han, Tomi K. Sawyer, Justin Noehre, Noriyuki Kawahata
  • PEPTIDOMIMETIC MACROCYCLES
    Publication number: 20120178700
    Abstract: The present invention provides novel peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease.
    Type: Application
    Filed: September 22, 2009
    Publication date: July 12, 2012
    Applicant: Aileron Therapeutics, Inc.
    Inventors: Huw M. Nash, Rosana Kapeller-Libermann, Jiawen Han, Tomi K. Sawyer, Justin Noehre
  • PEPTIDOMIMETIC MACROCYCLES
    Publication number: 20120115793
    Abstract: The present invention provides novel peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease.
    Type: Application
    Filed: September 22, 2009
    Publication date: May 10, 2012
    Applicant: Alleron Therapeutics, Inc
    Inventors: Huw M. Nash, Rosana Kapeller-Libermann, Jiawen Han, Tomi K. Sawyer, Justin Noehre
  • PEPTIDOMIMETIC MACROCYCLES
    Publication number: 20120115783
    Abstract: The present invention provides novel peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease.
    Type: Application
    Filed: September 22, 2009
    Publication date: May 10, 2012
    Applicant: Alleron therapeutics, Inc
    Inventors: Huw M. Nash, Rosana Kapeller-Libermann, Jiawen Han, Tomi K. Sawyer, Justin Noehre
  • PEPTIDOMIMETIC MACROCYCLES
    Publication number: 20120101047
    Abstract: The present invention provides novel peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease.
    Type: Application
    Filed: September 22, 2009
    Publication date: April 26, 2012
    Applicant: Aileron Therapetics Inc.
    Inventors: Huw M. Nash, Rosana Kapeller-Libermann, Jiawen Han, Tomi K. Sawyer, Justin Noehre