Abstract: A core needle biopsy device includes a needle assembly, a drive assembly, and a user interface. The needle assembly includes a piercer and a hollow cutter. The piercer includes a sharp distal tip and a notch proximal to the distal tip. The piercer is slidably disposed within the cutter to sever a tissue sample into the notch of the piercer. The drive assembly is configured to selectively move the piercer and the cutter. The user interface includes one or more indicators and a single button. The single button is configured to initiate a plurality of movements of the drive assembly to control arming and firing of the piercer and the cutter. The one or more indicators are configured to transition between a plurality of predetermined states to define one or more predetermined status sequences indicative of movement of the piercer and the cutter via the drive assembly.

Abstract: A core needle biopsy device includes a body, a needle assembly, a drive assembly, and a tissue sample holder. The body includes a housing defining a recess. The needle assembly includes a piercer and a hollow cutter. The piercer includes a sharp distal tip and a notch proximal to the distal tip. The piercer is slidably disposed within the cutter to sever a tissue sample into the notch of the piercer. The drive assembly is configured to selectively move the piercer and the cutter. The tissue sample holder is formed in the recess. The tissue sample holder has a removable cover, a driver, and a wiper. The cover is disposed over the recess. The housing and the cover together define a sample chamber. The driver is configured to move the wiper relative to a portion of the biopsy device to manipulate a severed tissue sample into the sample chamber.

Abstract: A core needle biopsy device includes a needle assembly, a drive assembly, and a tissue sample holder. The needle assembly includes a piercer and a hollow cutter. The piercer includes a sharp distal tip and a notch proximal to the distal tip. The piercer is slidably disposed within the cutter to sever a tissue sample into the notch of the piercer. The drive assembly is configured to selectively move the piercer and the cutter. The tissue sample holder has a sample chamber, a drive member, and a wiper. The driver being configured to bend the wiper against a portion of the biopsy device to manipulate a severed tissue sample into the sample chamber.

Abstract: A core needle biopsy device includes a needle assembly, a drive assembly, and a tissue sample holder. The needle assembly includes a piercer and a hollow cutter. The piercer includes a sharp distal tip and a notch proximal to the distal tip. The piercer is slidably disposed within the cutter to sever a tissue sample into the notch of the piercer. The drive assembly is configured to selectively move the piercer and the cutter. The tissue sample holder has a sample chamber and a wiper. The wiper is movable relative to the piercer and cutter to manipulate a severed tissue sample into the sample chamber.

Abstract: A core needle biopsy device includes a needle assembly, a drive assembly, and a user interface. The needle assembly includes a piercer and a hollow cutter. The piercer includes a sharp distal tip and a notch proximal to the distal tip. The piercer is slidably disposed within the cutter to sever a tissue sample into the notch of the piercer. The drive assembly is configured to selectively move the piercer and the cutter. The user interface has a plurality of indicators. Each indicator of the plurality of indicators is configured to independently transition between a plurality of predetermined states to collectively define a plurality of predetermined status sequences that indicate movement of the piercer and the cutter via the drive mechanism.

Abstract: A core needle biopsy device includes a needle assembly, a cutter drive assembly, a piercer drive assembly and an actuation mechanism. The needle assembly includes a piercer and a hollow cutter. The piercer includes a sharp distal tip and a notch proximal to the distal tip. The piercer is slidably disposed within the cutter to sever a tissue sample into the notch. The cutter drive assembly is configured to move the cutter. The piercer drive assembly is configured to move the piercer. The piercer drive assembly includes a lead screw configured to move both a portion of the cutter drive assembly and a portion of the piercer drive assembly. The actuation mechanism is configured to engage bot the cutter drive assembly and the piercer drive assembly to initiate firing of the piercer and the cutter sequentially using the cut drive assembly and the piercer drive assembly.

Abstract: A marker delivery device includes a grip, a cannula, a push rod, and a marker element. The cannula extends distally from the grip. The push rod is configured to move within the cannula and includes a distal end with one or more seals configured to seal against an interior of the cannula. The marker element includes one or more barbs. The push rod is configured to generate a pressure within the cannula between the one or more seals and the marker element to eject the marker element from the cannula.

Abstract: A biopsy device includes a probe, a needle, a cutter, and a manually actuated needle rotation assembly. The probe includes a probe housing. The needle extends from the probe. The cutter is disposed within the needle. The cutter defines a cutter lumen and at least partially defines a vent lumen between an exterior of the cutter and an interior of the needle. The needle rotation assembly includes a pinion shaft. A portion of the pinion shaft is exposed relative to the probe housing such that the pinion shaft is configured for actuation using a single hand while grasping the biopsy device with the single hand.

Abstract: A biopsy device includes a probe, a needle, a cutter, and a manually actuated needle firing assembly. The needle extends from the probe. The cutter is disposed within the needle. The cutter defines a cutter lumen and at least partially defines a vent lumen between an exterior of the cutter and an interior of the needle. The needle firing assembly includs a catch and a release. The catch is reliantly biased to fire the needle. The release is configured to engage the catch to thereby hold the catch in a cocked position.

Abstract: A medical device localization assembly includes an exterior frame, at least one lateral bar, a plurality of locating members and a targeting guide. The exterior frame includes a distal face configured to compress against tissue. The at least one lateral bar extends within the exterior frame and at least one open recess is formed between the lateral bar and the exterior frame. The plurality of locating members are positioned along an inner side of the exterior frame and the at least one lateral bar. The plurality of locating members extend into the at least one open recess and the at least one open recess is configured to removably receive the targeting guide at the proximal face. The plurality of locating members are sized and shaped to removably hold the guide cube such that the plurality of locating members are configured to correspond to the shape of the targeting guide.