Abstract: A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. Additional embodiments herein provide coupling constraint configured to interface with a coupling assembly during a histotripsy procedure.

Abstract: The present disclosure includes improved apparatuses and methods related to meat processing. One example method includes performing a first cut in association with a rinsing process performed on an animal, wherein performing the first cut includes severing at least one jugular vein of the animal; and subsequent to performing the first cut, performing a second cut that includes one of: making an incision in a vena cava of the animal that provides an exit location for treatment solution introduced into a circulatory system of the animal; and severing the vena cava of the animal such that the severed vena cava provides an exit location for treatment solution introduced into the circulatory system of the animal.

Abstract: The present disclosure includes improved apparatuses and methods related to meat processing. One example method includes performing a first cut in association with a rinsing process performed on an animal, wherein performing the first cut includes severing at least one jugular vein of the animal; and subsequent to performing the first cut, performing a second cut that includes one of: making an incision in a vena cava of the animal that provides an exit location for treatment solution introduced into a circulatory system of the animal; and severing the vena cava of the animal such that the severed vena cava provides an exit location for treatment solution introduced into the circulatory system of the animal.