Abstract: A biometric evaluation system for a vehicle includes a vision sensor configured to detect a biometric quality of a user. The biometric evaluation system also includes an operational system for the vehicle. At least one processor is in communication with the vision sensor. The processor is configured to execute a first classification algorithm that performs a first biometric validation based on the biometric quality to estimate a state of the user. The first classification algorithm requires a first service latency. In response to an outcome of the first biometric validation, the at least one processor is further configured to execute a second classification algorithm that performs a second biometric validation to confirm the state of the user. The second classification algorithm requires a second service latency greater than the first service latency. The processor is further configured to communicate a signal to modify operation of the vehicle.

Abstract: A method to prevent intoxicated operation is described. The method includes providing instructions to a vehicle user to position a vehicle user body portion posture in a predefined alignment. The method further includes obtaining the vehicle user body portion posture from a first vehicle detector, and determining whether the vehicle user body portion posture is in the predefined alignment. The method includes activating a plurality of vehicle visual indicators to illuminate in a predefined manner when the vehicle user body portion posture is in the predefined alignment. The method further includes providing instructions to the vehicle user to move vehicle user eyes to track the plurality of vehicle visual indicators, and obtaining a vehicle user eye movement from a second vehicle detector. The method further includes determining whether the vehicle user eye movement meets a predetermined condition, and actuating a control action accordingly.

Abstract: A system is described for monitoring the behaviour of a human or animal subject and optionally initiating one or more events in a domain in response to the behaviour. The system comprises a plurality of subject sensors for monitoring the subject's behaviour including one or more body worn sensors and optionally one or more remote sensors; a subject device to be worn by the subject and to receive sensor data from the body worn sensors and from the optional remote sensors. A server may be arranged to receive sensor data from the subject device and to transmit instructions based on the subject sensor data. A domain device may also be provided to be located in the domain and to receive instructions from the server; and a plurality of domain actuators for causing one or more events in the domain in response to instructions from the domain device.

Abstract: A one-hand engageable vacuum tool connection assembly for connection to a commercial vehicle vacuum system that includes: a vacuum tool connection assembly hose having a first end and a second end; an upper assembly and a lower assembly having a tool connector where the tool connector engages a second end of the lower assembly swivel cuff and is typically adapted to receive one or a plurality of different types of vacuum tools. The vacuum tool engagement assembly is typically free of any flapper valve, metal or spring biased elements.

Abstract: Disclosed herein are self-assembling protein nanoparticles comprising passenger molecules of interest.

Abstract: N(57) Abstract: There is a need for new and alternative options for immune therapy of proliferative diseases such as cancer. This need C\11 may be address by providing a chimeric antigen receptor having an extracellular domain including a binding domain which recognises Nthe cancer-stem-cell-associated protein Lgr5; a transmembrane domain; and an intracellular signalling domain that activates a cellular .,, function. Such CAR T cells can be used to kill cancer cells and treat or prevent cancer in a subject.

Abstract: A method for performing simultaneous operations at a wellsite comprising two or more adjacent wellheads, each respectively connected to a well, may include the following steps: providing a fluid supply via upstream equipment to an intermediate supply point; fluidly connecting the intermediate supply point to a single wellhead, the fluidly connecting comprising connecting a first end of a flexible pipe to the intermediate supply point and a second end of the flexible pipe to a first wellhead; performing a wellbore operation on a first well using the fluid supply from the upstream equipment supplied to the first wellhead; disconnecting the second end of the flexible pipe from the first wellhead; and connecting the second end of the flexible pipe to a second wellhead.

Abstract: A method for performing simultaneous operations at a wellsite comprising two or more adjacent wellheads, each respectively connected to a well, may include the following steps: providing a fluid supply via upstream equipment to an intermediate supply point; fluidly connecting the intermediate supply point to a single wellhead, the fluidly connecting comprising connecting a first end of a flexible pipe to the intermediate supply point and a second end of the flexible pipe to a first wellhead; performing a wellbore operation on a first well using the fluid supply from the upstream equipment supplied to the first wellhead; disconnecting the second end of the flexible pipe from the first wellhead; and connecting the second end of the flexible pipe to a second wellhead.

Abstract: The present disclosure includes a vacuum stall canopy assembly for a car wash system having a first post assembly having a base leg permanently attached to the ground, a beam attached to the top of the first post assembly, a roof assembly disposed on an upper portion of the beam, a debris separator disposed on the beam, the debris separator having a first side and a second side, a main airline fluidly connected to the debris separator and configured to be connected to a source of vacuum suction, a first hose on the first side of the debris separator, and having a first nozzle on a distal end of the hose from the debris separator, and a second hose on the second side of the debris separator, and having a second nozzle on a distal end of the hose from the debris separator.

Abstract: A method for performing simultaneous operations at a wellsite comprising two or more adjacent wellheads, each respectively connected to a well, may include the following steps: providing a fluid supply via upstream equipment to an intermediate supply point; fluidly connecting the intermediate supply point to a single wellhead, the fluidly connecting comprising connecting a first end of a flexible pipe to the intermediate supply point and a second end of the flexible pipe to a first wellhead; performing a wellbore operation on a first well using the fluid supply from the upstream equipment supplied to the first wellhead; disconnecting the second end of the flexible pipe from the first wellhead; and connecting the second end of the flexible pipe to a second wellhead.

Abstract: A vehicle vacuuming system that includes: a vacuum housing having an air filter, a motor within the interior volume of the vacuum housing wherein the motor supplies air suction power to a vacuum air intake distal from the motor and through a vacuum hose operably engaged with the vacuum housing, and an air outlet proximate the motor; and a pressure notification system chosen from the group consisting of a light, a speaker, a mobile application, and combinations thereof operably connected to a pressure sensing system associated with the vehicle vacuuming system.

Abstract: Viewers of a video stream may generate video clips including different portions of the video stream. Popularity measures may be computed for the video clips, for example based on tracked actions associated with the video clips, such as frequency of playing and sharing of the video clips. The popularity measures may be used to select and provide video clips to viewers. Video items may be generated by streamers, such as may include selected portions of video of streamers playing a game. A video item generated by a particular streamer may be displayed to viewers only during times when that particular streamer is participating in an active game session. Viewers of the video item may provide input that allows viewers to receive a live stream of the streamer's active game session that it is being played simultaneously with the display of the video item.

Abstract: The present invention relates to an optimized chimeric antigen receptor (CAR), and genetically modified cells expressing the same, that can target a diverse range of cancer types. More specifically, the CAR has an optimized linker length that facilitates the targeting and lyse of a wide range of cancer cell types by CAR expressing T cells.

Abstract: A method for performing simultaneous operations at a wellsite comprising two or more adjacent wellheads, each respectively connected to a well, may include the following steps: providing a fluid supply via upstream equipment to an intermediate supply point; fluidly connecting the intermediate supply point to a single wellhead, the fluidly connecting comprising connecting a first end of a flexible pipe to the intermediate supply point and a second end of the flexible pipe to a first wellhead; performing a wellbore operation on a first well using the fluid supply from the upstream equipment supplied to the first wellhead; disconnecting the second end of the flexible pipe from the first wellhead; and connecting the second end of the flexible pipe to a second wellhead.

Abstract: A mattress for institutional use provides upper and lower surfaces offering different levels of firmness through the use of gradiated firmness in multiple polymer foam layers.