Abstract: Fluid regulators are disclosed. An example apparatus includes a vale body, a valve seat, and protrusions. The valve body has an inlet and an outlet. The valve seat is located within the valve body and is positioned between the inlet and the outlet. The protrusions are formed by and extend along an inner wall of the valve body between the valve seat and the outlet, and end adjacent the outlet. At least one of the protrusions is spaced relative to others of the protrusions. The protrusions are to increase a uniformity of a flow pattern of fluid flowing through a cross-section of the outlet. Each of the protrusions has a central axis oriented perpendicularly to a corresponding surrounding portion of the inner wall.

Abstract: Fluid regulators are disclosed. An example a valve body including an inlet, an outlet, and an aperture disposed between the inlet and the outlet, the outlet includes surface structures to increase a uniformity of a flow pattern of fluid flowing through a cross-section of the outlet.

Abstract: Spring seat vibration damper apparatus for use with fluid pressure regulators are disclosed. A disclosed apparatus includes a first spring seat of a fluid pressure regulator defining a first protrusion and a second spring seat of the fluid pressure regulator defining a second protrusion. The second protrusion is configured to receive at least a portion of the first protrusion. The first spring seat moves relative to the second spring seat to provide a damping effect between the protrusions.

Abstract: Fluid regulators are disclosed. An example a valve body including an inlet, an outlet, and an aperture disposed between the inlet and the outlet, the outlet includes surface structures to increase a uniformity of a flow pattern of fluid flowing through a cross-section of the outlet.

Abstract: A rotary fluid machine 10 has a rotor 12, a stator 14, and a plurality of gates. The rotor 12 and stator 14 are rotatable relative to each other and arranged one inside the other to define a working chamber 18 there between. Gates 16 are supported in radial gate slots 20 formed in the rotor 12 and cyclically extend from and retract into the gate slots 20 as the rotor 12 rotates about stator 14. A plurality of demountable lobes is supported on an outer circumferential surface 24 of stator 14. The surface 24 forms a surface of the working chamber 18. Circumferential surface 24 is composed of an intermediate surface 48 which extends in an axial direction and opposite curved surfaces 46. The gate 16 has opposite rounded corners 130 separated by an axial planar surface 132.

Abstract: A pressure sensor device and its use for confirming achievement of a selected pressure in a high pressure process (HPP) for sanitizing food is disclosed. The device includes at least a base and a sheet, each of which is substantially impermeable to the working fluid of the HPP and is deformable at the selected pressure. Microcapsules interposed between flat overlapping portions of the base and sheet contain a color former and burst upon pressurization of the environment surrounding the device. Release of the color former is detected to confirm that the pressurization occurred. The device can be associated with one or more foodstuffs (e.g., a packaged food product or a group of such packages) and remain associated therewith to continuously indicate that the foodstuff(s) have been subjected to the selected pressure and are therefore sanitized.

Abstract: The present invention relates to methods of identifying gene targets, including methods of using ribonucleoprotein (RNP) immunoprecipitation-microarrays to identify cancer gene targets, such as subsets of RNP-associated mRNAs in breast cancer cell lines. Also presented, are ribonucleotide binding protein-associated biomarkers, panels or sets of ribonucleotide binding protein-associated biomarkers, methods and compositions comprising ribonucleotide-binding protein, associated nucleotides, nucleotide arrays, and kits, plus methods of using HuR-associated biomarkers to facilitate the diagnosis of, monitoring the disease status of, and the progression of treatment of breast cancers to facilitate the diagnosis of and monitoring the disease status or progression of treatment of breast cancers, including drug-resistant breast cancers.

Abstract: A pressure sensor device and its use for confirming achievement of a selected pressure in a high pressure process (HPP) for sanitizing food is disclosed. The device includes at least a base and a sheet, each of which is substantially impermeable to the working fluid of the HPP and is deformable at the selected pressure. Microcapsules interposed between flat overlapping portions of the base and sheet contain a color former and burst upon pressurization of the environment surrounding the device. Release of the color former is detected to confirm that the pressurization occurred. The device can be associated with one or more foodstuffs (e.g., a packaged food product or a group of such packages) and remain associated therewith to continuously indicate that the foodstuff(s) have been subjected to the selected pressure and are therefore sanitized.

Abstract: A rotary fluid machine 10 has a rotor 12, a stator 14, and a plurality of gates. The rotor 12 and stator 14 are rotatable relative to each other and arranged one inside the other to define a working chamber 18 there between. Gates 16 are supported in radial gate slots 20 formed in the rotor 12 and cyclically extend from and retract into the gate slots 20 as the rotor 12 rotates about stator 14. A plurality of demountable lobes is supported on an outer circumferential surface 24 of stator 14. The surface 24 forms a surface of the working chamber 18. Circumferential surface 24 is composed of an intermediate surface 48 which extends in an axial direction and opposite curved surfaces 46. The gate 16 has opposite rounded corners 130 separated by an axial planar surface 132.

Abstract: A pressure sensor device and its use for confirming achievement of a selected pressure in a high pressure process (HPP) for sanitizing food is disclosed. The device includes at least a base and a sheet, each of which is substantially impermeable to the working fluid of the HPP and is deformable at the selected pressure. Microcapsules interposed between flat overlapping portions of the base and sheet contain a color former and burst upon pressurization of the environment surrounding the device. Release of the color former is detected to confirm that the pressurization occurred. The device can be associated with one or more foodstuffs (e.g., a packaged food product or a group of such packages) and remain associated therewith to continuously indicate that the foodstuff(s) have been subjected to the selected pressure and are therefore sanitized.

Abstract: The disclosure relates to methods of treating whole, cut, or other processed botanical ingredient(s) in a manner that reduces the load of viable food-contaminating organisms (human or other animal pathogens and food spoilage organisms), preferably without substantially altering one or more of the organoleptic properties of the ingredient(s). The method includes subjecting a botanical foodstuff to a high pressure processing (HPP) treatment and to aseptically sealing the foodstuff within a package that contains a microbistat. Such treatments improve the storage stability of the foodstuff and preferably do not significantly alter one or more organoleptic properties of the botanical ingredient(s). Packaged foodstuffs treated as described herein exhibit beneficial properties, such as retention of taste, appearance, and texture and extended shelf life, relative to non-treated foodstuffs.

Abstract: The disclosure relates to method of treating foodstuffs such as whole or cut vegetables or fruits or cuts of meat in a manner that reduces the load of human or other animal pathogens in the foodstuff, preferably without substantially altering its appearance, one or more of its organoleptic properties, or some combination of these. The method includes contacting the foodstuff with a pathogenostatic fluid such as an acidic solution, preferably at a reduced pressure, and thereafter subjecting the foodstuff to an HPP process. Foodstuffs treated in this manner can be packaged in the presence of the pathogenostatic fluid, in the presence of a sauce, or in the presence of substantially no liquid. Packaged foodstuffs treated as described herein exhibit beneficial properties, such as retention of taste, appearance, and texture and extended shelf life, relative to non-treated foodstuffs.

Abstract: A pressure sensor device and its use for confirming achievement of a selected pressure in a high pressure process (HPP) for sanitizing food is disclosed. The device includes at least a base and a sheet, each of which is substantially impermeable to the working fluid of the HPP and is deformable at the selected pressure. Microcapsules interposed between flat overlapping portions of the base and sheet contain a color former and burst upon pressurization of the environment surrounding the device. Release of the color former is detected to confirm that the pressurization occurred. The device can be associated with one or more foodstuffs (e.g., a packaged food product or a group of such packages) and remain associated therewith to continuously indicate that the foodstuff(s) have been subjected to the selected pressure and are therefore sanitized.

Abstract: A caster for use in aircraft along a cargo deck comprises a housing having at least one wall, a pivot assembly, a brake assembly and at least one spring. A pivot assembly can have at least one wall, first and second ends, and a base between the first and second ends, wherein the first end of the pivot assembly can be elevated above the second end of the pivot assembly. The wall of the pivot assembly can be rotatably linked to the wall of the housing. An optional brake assembly can be on the first end of the pivot assembly. At least one spring can be on the second end of the pivot assembly. A cover on or above the at least one spring can be secured to the wall of the housing.

Abstract: A manually operated detail sander comprises a first plate, a second plate and a sheet of sanding material. The first plate has uniform thickness and includes first and second sides that define a sculpting profile. The second plate has the thickness of the first plate and has an ergonomic profile including an elongate fastening edge extending at least partially across and joined to the first side of the first plate. The sheet of sanding material extends across the second side of the first plate.

Abstract: The present invention relates to methods of identifying gene targets, including methods of using ribonucleoprotein (RNP) immunoprecipitation-microarrays to identify cancer gene targets, such as subsets of RNP-associated mRNAs in breast cancer cell lines. Also presented, are ribonucleotide binding protein-associated biomarkers, panels or sets of ribonucleotide binding protein-associated biomarkers, methods and compositions comprising ribonucleotide-binding protein, associated nucleotides, nucleotide arrays, and kits to facilitate the diagnosis of and monitoring the disease status or progression of treatment of breast cancers, including drug-resistant breast cancers.

Abstract: A caster for use in aircraft along a cargo deck comprises a housing having at least one wall, a pivot assembly, a brake assembly and at least one spring. A pivot assembly can have at least one wall, first and second ends, and a base between the first and second ends, wherein the first end of the pivot assembly can be elevated above the second end of the pivot assembly. The wall of the pivot assembly can be rotatably linked to the wall of the housing. An optional brake assembly can be on the first end of the pivot assembly. At least one spring can be on the second end of the pivot assembly. A cover on or above the at least one spring can be secured to the wall of the housing.

Abstract: A multi-use wayside railway control system for installation and use in operating wayside railway equipment in a railway wayside application selected from among a plurality of differing railway wayside applications usable in the control system. The system includes detectors responsive to and generating data indicative of operating conditions of the selected wayside application A controller receives data from the detectors and is responsive to the data for operating the wayside equipment. A programmed processor associated with the controller includes a software program storage device for storing a plurality of separately selectable operating programs, each of the operating programs comprising application specific information for a selected wayside application and corresponding configuration of wayside equipment.

Abstract: A control valve system is disclosed which provides a mechanism by which the valve can be moved to its fail-safe position. The system includes a valve actuator which receives pressurized fluid from a regulator. The regulator is provided with a reverse pressure exhaust valve such that if pressure within the valve actuator is to be alleviated, as when the valve is to be positioned into its fail-safe position, the reverse pressure exhaust valve is opened thereby providing an immediate and accurate passageway through which excess pressure within the regulator outlet can be alleviated.