Patents by Inventor Justine Cunningham

Justine Cunningham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING GLYCOGEN STORAGE DISORDERS
    Publication number: 20220387562
    Abstract: The present disclosure relates to compositions and methods useful for treating glycogen storage disorders, such as type II glycogen storage disorder, also referred to herein as Pompe disease. Using the compositions and methods of the disclosure, a patient (e.g., a mammalian patient, such as a human patient) having Pompe disease may be administered a viral vector, such as an adeno-associated viral (AAV) vector, that contains a transgene encoding acid alpha-glucosidase.
    Type: Application
    Filed: October 23, 2020
    Publication date: December 8, 2022
    Inventors: John T. GRAY, Justine CUNNINGHAM, Salvador RICO
  • Cells that lack p19ink4d and p27kip1 activity and methods of use thereof
    Patent number: 6589505
    Abstract: Non-human animals that have been manipulated so as not to express a functional p19INK4d and p27KIP1 proteins are described. One particular non-human animal exemplified is a p19INK4d-double null, p27KIP1-double null mouse. Such knockout mice exhibit bradykinesia, proprioceptive abnormalities, seizure-like activity, and generally die 14-24 days after birth. In addition, mammalian cells having the p19INK4d-double null, p27KIP1-double null genotype are characterized. Methods of making and using the non-human knockout animals and cells are disclosed.
    Type: Grant
    Filed: January 14, 2000
    Date of Patent: July 8, 2003
    Assignee: St. Jude Children's Research Hospital
    Inventors: Martine F. Roussel, Richard Smeyne, Frederique Zindy, Justine Cunningham, Neil Segil, Ping Chen
  • Knockout mice and cells that lack p19INK4d and p27KIP1 activity and methods of use thereof
    Patent number: 6245965
    Abstract: Non-human animals that have been manipulated so as not to express a functional p19INK4d and p27KIP1 proteins are described. One particulat non-human animal exemplified is a p19INK4d-double null, p27KIP1-double null mouse. Such knockout mice exhibit bradykinesia, proprioceptive abnormalties, seizure-like activity, and generally die 14-24 days after birth. In addition, mammalian cells having the p19INK4d-double null, p27KIP1-double null genotype are characterized. Methods of making and using the non-human knockout animals and cells are disclosed.
    Type: Grant
    Filed: January 29, 1999
    Date of Patent: June 12, 2001
    Assignee: St. Jude Children's Research Hospital
    Inventors: Martine F. Roussel, Richard Smeyne, Frederique Zindy, Justine Cunningham