Patents by Inventor Justine D. Miller

Justine D. Miller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AGE-MODIFIED CELLS AND METHODS FOR MAKING AGE-MODIFIED CELLS
    Publication number: 20180230424
    Abstract: Provided are age-modified cells and method for making age modified cells using progerin or a progerin-like protein. The aging and/or maturation process can be accelerated and controlled for young and/or immature cells, such as a somatic cell, a stem cell, a stem cell-derived somatic cell, including an induced pluripotent stem cell-derived cell, by contacting with progerin or a progerin-like protein. Methods described by the present disclosure can produce age-appropriate cells from a somatic cell or a stem cell, such as an old cell and/or a mature cell. Such age-modified cells constitute model systems for the study of late-onset diseases and/or disorders.
    Type: Application
    Filed: April 2, 2018
    Publication date: August 16, 2018
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Lorenz Studer, Justine D. Miller
  • Age-modified cells and methods for making age-modified cells
    Patent number: 9963674
    Abstract: Provided are age-modified cells and method for making age modified cells using progerin or a progerin-like protein. The aging and/or maturation process can be accelerated and controlled for young and/or immature cells, such as a somatic cell, a stem cell, a stem cell-derived somatic cell, including an induced pluripotent stem cell-derived cell, by contacting with progerin or a progerin-like protein. Methods described by the present disclosure can produce age-appropriate cells from a somatic cell or a stem cell, such as an old cell and/or a mature cell. Such age-modified cells constitute model systems for the study of late-onset diseases and/or disorders.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: May 8, 2018
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Lorenz Studer, Justine D. Miller
  • AGE-MODIFIED CELLS AND METHODS FOR MAKING AGE-MODIFIED CELLS
    Publication number: 20160115444
    Abstract: Provided are age-modified cells and method for making age modified cells using progerin or a progerin-like protein. The aging and/or maturation process can be accelerated and controlled for young and/or immature cells, such as a somatic cell, a stem cell, a stem cell-derived somatic cell, including an induced pluripotent stem cell-derived cell, by contacting with progerin or a progerin-like protein. Methods described by the present disclosure can produce age-appropriate cells from a somatic cell or a stem cell, such as an old cell and/or a mature cell. Such age-modified cells constitute model systems for the study of late-onset diseases and/or disorders.
    Type: Application
    Filed: October 15, 2015
    Publication date: April 28, 2016
    Applicant: Memorial Sloan-Kettering Cancer Center
    Inventors: LORENZ STUDER, Justine D. Miller