Patents by Inventor Justis P. Ehlers

Justis P. Ehlers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10888455
    Abstract: Systems and methods are provided for image-guided delivery of therapeutics to an eye. An optical coherence tomography (OCT) imager is configured to produce at least one OCT image of the eye. A therapeutic delivery system is configured to deliver a therapeutic to the eye through a distal end of a delivery mechanism. A system control is configured to determine a position of the distal end of the delivery mechanism and control the therapeutic delivery system according to at least the determined position.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: January 12, 2021
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Sunil K. Srivastava, Justis P. Ehlers, Yuankai K. Tao
  • Patent number: 10628940
    Abstract: Systems and methods are provided for automated analysis of angiographic images. An angiographic imaging system is configured to capture a first image of a region of interest, representing a first time, and a second image of a region of interest, representing a second time. A registration component is configured to register the first image to the second image. A difference component is configured to generate a difference image from the first image and the second image. A pattern recognition component is configured to assign a clinical parameter to the region of interest from the difference image and at least one of the first image and the second image.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: April 21, 2020
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Sunil K. Srivastava, Justis P. Ehlers
  • Publication number: 20200077883
    Abstract: Systems and methods are provided for evaluating an eye using retinal fluid volumes to provide a clinical parameter. An optical coherence tomography (OCT) image of an eye of a patient is obtained. The OCT image is segmented to produce a total retinal volume and one or both of a subretinal fluid volume and an intraretinal fluid volume for a region of interest within the eye. A metric is generated as a function of the total retinal volume and one or both of the subretinal fluid volume and the intraretinal fluid volume. A clinical parameter for the patient is determined from the metric. The determined clinical parameter is provided to a user at a display.
    Type: Application
    Filed: September 12, 2019
    Publication date: March 12, 2020
    Inventors: Justis P. Ehlers, Atsuro Uchida, Sunil Srivastava
  • Publication number: 20190231591
    Abstract: Systems and methods are provided for image-guided delivery of therapeutics to an eye. An optical coherence tomography (OCT) imager is configured to produce at least one OCT image of the eye. A therapeutic delivery system is configured to deliver a therapeutic to the eye through a distal end of a delivery mechanism. A system control is configured to determine a position of the distal end of the delivery mechanism and control the therapeutic delivery system according to at least the determined position.
    Type: Application
    Filed: April 11, 2019
    Publication date: August 1, 2019
    Inventors: Sunil K. Srivastava, Justis P. Ehlers, Yuankai K. Tao
  • Patent number: 10278859
    Abstract: Systems and methods are provided for image-guided delivery of therapeutics to an eye. An optical coherence tomography (OCT) imager is configured to produce at least one OCT image of the eye. A therapeutic delivery system is configured to deliver a therapeutic to the eye through a distal end of a delivery mechanism. A system control is configured to determine a position of the distal end of the delivery mechanism and control the therapeutic delivery system according to at least the determined position.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: May 7, 2019
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Sunil K. Srivastava, Justis P. Ehlers, Yuankai K. Tao
  • Patent number: 10058243
    Abstract: Systems and methods are provided for evaluating an eye of a patient from a set of OCT data. A layer segmentation component is configured to identify and segment a plurality of retinal layers within the set of OCT data. The plurality of layers include a layer of interest. A mapping component is configured to generate at least one of an en face representation of the layer of interest and a three-dimensional reconstruction of the layer of interest from the segmented plurality of layers. A parameter generator is configured to derive at least one parameter, representing a thickness of the layer of interest, from the at least one of the en face representation of the layer of interest and the three-dimensional reconstruction of the layer of interest. A user interface is configured to provide the determined at least one parameter to a display.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: August 28, 2018
    Assignee: The Cleveland Clinic Foundation
    Inventors: Justis P. Ehlers, Sunil Srivastava
  • Patent number: 10052016
    Abstract: Systems and methods are provided for evaluating an eye of a patient. A first imager interface receives a first image of at least a portion of the eye generated via a first imaging modality, and a second imager interface receives a second image of at least a portion of the eye generated via a second imaging modality. A first feature extractor extracts a first set of numerical features from the first image, with one feature representing a spatial extent of one of a tissue layer, a tissue structure, and a pathological feature. A second feature extractor extracts a second set of numerical features from the second image, with one feature representing one of a number and a location of vascular irregularities within the eye. A pattern recognition component evaluates the first plurality of features and the second plurality of features to assign a clinical parameter to the eye.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: August 21, 2018
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Justis P. Ehlers, Sunil Srivastava
  • Patent number: 9946046
    Abstract: An apparatus for selectively connecting an accessory item to a surgical microscope includes a center pivot. An adapter arm includes an adapter support having a substantially planar support body which extends laterally in an outboard direction from the center pivot and has laterally spaced inboard and outboard support regions separated by a laterally oriented centerline. The adapter arm is configured to accept at least a portion of the accessory item in a supporting relationship. An undermount adapter includes a substantially planar undermount body having laterally spaced inboard and outboard body regions separated by a laterally oriented centerline. A plurality of microscope attachment throughholes each throughhole extend through the undermount body. Each throughhole is configured to accept a fastener for securement of the undermount adapter to the surgical microscope. An arm receiver is configured to accept the adapter tongue of the adapter arm in a supporting relationship.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: April 17, 2018
    Assignee: The Cleveland Clinic Foundation
    Inventors: Justis P. Ehlers, Sunil K. Srivastava
  • Patent number: 9848770
    Abstract: A surgical imaging system is provided. The surgical imaging system includes a surgical microscope and a telecentric optical coherence tomography scanning unit configured to scan a sample through at least one optical component associated with the surgical microscope.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: December 26, 2017
    Assignee: The Cleveland Clinic Foundation
    Inventors: Justis P. Ehlers, Yuankai K. Tao, Sunil K. Srivastava
  • Patent number: 9703066
    Abstract: An apparatus for selectively connecting an accessory item to a surgical microscope includes a center pivot. An adapter arm includes an adapter support having a substantially planar support body which extends laterally in an outboard direction from the center pivot and has laterally spaced inboard and outboard support regions separated by a laterally oriented centerline. The adapter arm is configured to accept at least a portion of the accessory item in a supporting relationship. An undermount adapter includes a substantially planar undermount body having laterally spaced inboard and outboard body regions separated by a laterally oriented centerline. A plurality of microscope attachment throughholes each throughhole extend through the undermount body. Each throughhole is configured to accept a fastener for securement of the undermount adapter to the surgical microscope. An arm receiver is configured to accept the adapter tongue of the adapter arm in a supporting relationship.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: July 11, 2017
    Assignee: The Cleveland Clinic Foundation
    Inventors: Justis P. Ehlers, Sunil K. Srivastava
  • Publication number: 20170156582
    Abstract: Systems and methods are provided for evaluating an eye of a patient. A first imager interface receives a first image of at least a portion of the eye generated via a first imaging modality, and a second imager interface receives a second image of at least a portion of the eye generated via a second imaging modality. A first feature extractor extracts a first set of numerical features from the first image, with one feature representing a spatial extent of one of a tissue layer, a tissue structure, and a pathological feature. A second feature extractor extracts a second set of numerical features from the second image, with one feature representing one of a number and a location of vascular irregularities within the eye. A pattern recognition component evaluates the first plurality of features and the second plurality of features to assign a clinical parameter to the eye.
    Type: Application
    Filed: December 5, 2016
    Publication date: June 8, 2017
    Inventors: Justis P. Ehlers, Sunil Srivastava
  • Publication number: 20160242639
    Abstract: Systems and methods are provided for evaluating an eye of a patient from a set of OCT data. A layer segmentation component is configured to identify and segment a plurality of retinal layers within the set of OCT data. The plurality of layers include a layer of interest. A mapping component is configured to generate at least one of an en face representation of the layer of interest and a three-dimensional reconstruction of the layer of interest from the segmented plurality of layers. A parameter generator is configured to derive at least one parameter, representing a thickness of the layer of interest, from the at least one of the en face representation of the layer of interest and the three-dimensional reconstruction of the layer of interest. A user interface is configured to provide the determined at least one parameter to a display.
    Type: Application
    Filed: February 25, 2016
    Publication date: August 25, 2016
    Inventors: Justis P. Ehlers, Sunil Srivastava
  • Publication number: 20160106583
    Abstract: Systems and methods are provided for image-guided delivery of therapeutics to an eye. An optical coherence tomography (OCT) imager is configured to produce at least one OCT image of the eye. A therapeutic delivery system is configured to deliver a therapeutic to the eye through a distal end of a delivery mechanism. A system control is configured to determine a position of the distal end of the delivery mechanism and control the therapeutic delivery system according to at least the determined position.
    Type: Application
    Filed: October 19, 2015
    Publication date: April 21, 2016
    Inventors: Sunil K. Srivastava, Justis P. Ehlers, Yuankai K. Tao
  • Patent number: 9299139
    Abstract: Systems and methods are provided for volumetric analysis of pathologies. A segmentation component is configured to determine, for each of a series of images of a region of interest containing a pathological feature, a set of segmentation boundaries within the image representing a cross-section of the pathological feature. A mesh generation component is configured to link the sets of segmentation boundaries from adjacent images in the series of images to generate a polygonal mesh representing a volumetric reconstruction of the pathological feature. A volumetric measurement component is configured to calculate volumetric parameters from the volumetric reconstruction representing the pathological feature. A user interface is configured to provide the calculated volumetric parameters to an associated display.
    Type: Grant
    Filed: March 26, 2013
    Date of Patent: March 29, 2016
    Assignee: The Cleveland Clinic Foundation
    Inventors: Justis P. Ehlers, David Xu, Peter K. Kaiser, William J. Dupps, Sunil K. Srivastava
  • Publication number: 20160071266
    Abstract: Systems and methods are provided for automated analysis of angiographic images. An angiographic imaging system is configured to capture a first image of a region of interest, representing a first time, and a second image of a region of interest, representing a second time. A registration component is configured to register the first image to the second image. A difference component is configured to generate a difference image from the first image and the second image. A pattern recognition component is configured to assign a clinical parameter to the region of interest from the difference image and at least one of the first image and the second image.
    Type: Application
    Filed: September 8, 2015
    Publication date: March 10, 2016
    Inventors: Sunil K. Srivastava, Justis P. Ehlers
  • Publication number: 20150342460
    Abstract: Imaging and visualization systems, instruments, and methods using optical coherence tomography (OCT) are disclosed. A method for OCT image capture includes determining a location of a feature of interest within an operative field. The method also includes determining a relative positioning between the feature of interest and an OCT scan location. Further, the method includes controlling capture of an OCT image at a set position relative to the feature of interest based on the relative positioning.
    Type: Application
    Filed: August 11, 2015
    Publication date: December 3, 2015
    Inventors: Joseph A. Izatt, Cynthia A. Toth, Sina Farsiu, Paul V. Hahn, Yuankai K. Tao, Justis P. Ehlers, Justin V. Migacz, Stephanie J. Chiu
  • Publication number: 20150055093
    Abstract: A surgical imaging system is provided. The surgical imaging system includes a surgical microscope and a telecentric optical coherence tomography scanning unit configured to scan a sample through at least one optical component associated with the surgical microscope.
    Type: Application
    Filed: August 22, 2014
    Publication date: February 26, 2015
    Inventors: Justis P. Ehlers, Yuankai K. Tao, Sunil K. Srivastava
  • Publication number: 20140221822
    Abstract: Systems and methods are provided for tracking a depth of a surgical instrument in an optical coherence tomography (OCT) guided surgical procedure. An OCT device is configured to image a region of interest to provide OCT data. A scan processor is configured to determine a relative position of the instrument and a target within the region of interest from at least the OCT data, where the instrument is one of in front of the target, within the target, or below the target. A feedback element is configured to communicate the relative position of the instrument and the target to a user in a human comprehensible form.
    Type: Application
    Filed: February 4, 2014
    Publication date: August 7, 2014
    Applicant: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Justis P. Ehlers, Sunil K. Srivastava, Yuankai Tao
  • Publication number: 20140119624
    Abstract: Systems and methods are provided for volumetric analysis of pathologies. A segmentation component is configured to determine, for each of a series of images of a region of interest containing a pathological feature, a set of segmentation boundaries within the image representing a cross-section of the pathological feature. A mesh generation component is configured to link the sets of segmentation boundaries from adjacent images in the series of images to generate a polygonal mesh representing a volumetric reconstruction of the pathological feature. A volumetric measurement component is configured to calculate volumetric parameters from the volumetric reconstruction representing the pathological feature. A user interface is configured to provide the calculated volumetric parameters to an associated display.
    Type: Application
    Filed: March 26, 2013
    Publication date: May 1, 2014
    Applicant: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Justis P. Ehlers, David Xu, Peter K. Kaiser, William J. Dupps, Sunil K. Srivastava
  • Publication number: 20140085714
    Abstract: An apparatus for selectively connecting an accessory item to a surgical microscope includes a center pivot. An adapter arm includes an adapter support having a substantially planar support body which extends laterally in an outboard direction from the center pivot and has laterally spaced inboard and outboard support regions separated by a laterally oriented centerline. The adapter arm is configured to accept at least a portion of the accessory item in a supporting relationship. An undermount adapter includes a substantially planar undermount body having laterally spaced inboard and outboard body regions separated by a laterally oriented centerline. A plurality of microscope attachment throughholes each throughhole extend through the undermount body. Each throughhole is configured to accept a fastener for securement of the undermount adapter to the surgical microscope. An arm receiver is configured to accept the adapter tongue of the adapter arm in a supporting relationship.
    Type: Application
    Filed: September 27, 2013
    Publication date: March 27, 2014
    Applicant: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Justis P. Ehlers, Sunil K. Srivastava