Patents by Inventor Juven Lara
Juven Lara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10495552Abstract: A breath analysis system that includes a handle assembly with an analysis cartridge on an upper end thereof. The handle includes a main body portion with a pressure opening and a pressure transducer therein. The analysis cartridge includes a main body portion with an upper portion that defines a breath chamber, a lower portion that defines a fluid chamber and a filter assembly that is movable between a breath capture position and an analysis position. The filter assembly has an opening defined therethrough. In the breath capture position, the opening partially defines the breath chamber and in the analysis position the opening partially defines the fluid chamber. The system also includes an analysis device with a case, a door, a controller that controls the motor and a fluorescence detection assembly and a rotation assembly positioned in the case interior. The rotation assembly includes a shroud with a funnel portion for receiving the analysis cartridge.Type: GrantFiled: November 14, 2016Date of Patent: December 3, 2019Assignee: Pulse Health LLCInventors: Steve Cooper, Neal Andrews, Maura Mahon, Rachel Dreilinger, David Barsic, Weston Myler, Martin Krauss, Scot Herbst, James Ingle, Gerald Thomas, Rick Myers, Brian Young, Juven Lara, Charles Noll
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Publication number: 20190257757Abstract: Systems and methods directed to aldehyde detection are disclosed. An aldehyde detection system may capture aldehydes from a patient breath sample. Aldehydes of the breath sample may be used to form a mobile chromatography phase within an analysis device. The analysis device may include various modules configured to perform a high pressure liquid chromatography process that separates aldehydes according to size. A detection assembly may detect a relative value of the separated aldehydes. The analysis device may be configured to determine an aldehyde score or metric based on the detected aldehydes, which may assist in the diagnosis of certain medical conditions.Type: ApplicationFiled: May 3, 2019Publication date: August 22, 2019Inventors: Gerald Thomas, Juven Lara, Brian Young, Charles Noll, Craig Carlsen, James Ingle
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Publication number: 20190170614Abstract: An analysis cartridge the includes a main body portion and a filter assembly. The main body portion includes an upper portion that defines an upper chamber and a lower portion that defines a fluid chamber. The filter assembly is movable along a filter assembly path between a first position and a second position. The filter assembly has an opening defined therethrough. In the first position, the opening partially defines the upper chamber and in the second position the opening partially defines the fluid chamber.Type: ApplicationFiled: February 4, 2019Publication date: June 6, 2019Inventors: Martin Krauss, Maura Mahon, Andrew King, Steve Cooper, James Ingle, Gerald Thomas, David Barsic, Neal Andrews, Brian Young, Juven Lara, Charles Noll
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Publication number: 20190041332Abstract: Methods, systems and reagents are provided for detecting and quantifying carbonyl containing moieties in a variety of sample types.Type: ApplicationFiled: July 31, 2018Publication date: February 7, 2019Inventors: Gerald Thomas, Charles Noll, Juven Lara, Brian Young, Craig Carlsen, Bruce Branchaud, James Ingle
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Patent number: 10197477Abstract: An analysis cartridge the includes a main body portion and a filter assembly. The main body portion includes an upper portion that defines an upper chamber and a lower portion that defines a fluid chamber. The filter assembly is movable along a filter assembly path between a first position and a second position. The filter assembly has an opening defined therethrough. In the first position, the opening partially defines the upper chamber and in the second position the opening partially defines the fluid chamber.Type: GrantFiled: January 17, 2017Date of Patent: February 5, 2019Assignee: Pulse Health LLCInventors: Martin Krauss, Maura Mahon, Andrew King, Steve Cooper, James Ingle, Gerald Thomas, David Barsic, Neal Andrews, Brian Young, Juven Lara, Charles Noll
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Patent number: 9797815Abstract: A breath analysis system that includes a handle assembly with an analysis cartridge on an upper end thereof. The handle includes a main body portion with a pressure opening and a pressure transducer therein. The analysis cartridge includes a main body portion with an upper portion that defines a breath chamber, a lower portion that defines a fluid chamber and a filter assembly that is movable between a breath capture position and an analysis position. The filter assembly has an opening defined therethrough. In the breath capture position, the opening partially defines the breath chamber and in the analysis position the opening partially defines the fluid chamber. The system also includes an analysis device with a case, a door, a controller that controls the motor and a fluorescence detection assembly and a rotation assembly positioned in the case interior. The rotation assembly includes a shroud with a funnel portion for receiving the analysis cartridge.Type: GrantFiled: June 29, 2015Date of Patent: October 24, 2017Assignee: Pulse Health LLCInventors: Steve Cooper, Neal Andrews, Martin Krauss, Andrew E. King, Maura Mahon, Weston Myler, James Ingle, Gerald Thomas, Rachel Dreilinger, David Barsic, Rick Myers, Craig Carlsen, Scot Herbst, Brian Young, Juven Lara, Charles Noll
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Publication number: 20170284905Abstract: An analysis cartridge the includes a main body portion and a filter assembly. The main body portion includes an upper portion that defines an upper chamber and a lower portion that defines a fluid chamber. The filter assembly is movable along a filter assembly path between a first position and a second position. The filter assembly has an opening defined therethrough. In the first position, the opening partially defines the upper chamber and in the second position the opening partially defines the fluid chamber.Type: ApplicationFiled: January 17, 2017Publication date: October 5, 2017Inventors: Martin Krauss, Maura Mahon, Andrew King, Steve Cooper, James Ingle, Gerald Thomas, David Barsic, Neal Andrews, Brian Young, Juven Lara, Charles Noll
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Publication number: 20170242018Abstract: Methods, systems and reagents are provided for detecting and quantifying carbonyl containing moieties in a variety of sample types. The amount of time elapsed from capturing of the carbonyl containing moieties from a sample to the detection of the carbonyl containing moieties is less than about 2 hours. Compounds are provided to facilitate labeling and detection of the carbonyl containing moieties.Type: ApplicationFiled: February 17, 2017Publication date: August 24, 2017Inventors: Gerald Thomas, Juven Lara, Charles Noll, Brian Young, Craig Carlsen, Maura Mahon, James Ingle
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Publication number: 20170199125Abstract: A breath analysis system that includes a handle assembly with an analysis cartridge on an upper end thereof. The handle includes a main body portion with a pressure opening and a pressure transducer therein. The analysis cartridge includes a main body portion with an upper portion that defines a breath chamber, a lower portion that defines a fluid chamber and a filter assembly that is movable between a breath capture position and an analysis position. The filter assembly has an opening defined therethrough. In the breath capture position, the opening partially defines the breath chamber and in the analysis position the opening partially defines the fluid chamber. The system also includes an analysis device with a case, a door, a controller that controls the motor and a fluorescence detection assembly and a rotation assembly positioned in the case interior. The rotation assembly includes a shroud with a funnel portion for receiving the analysis cartridge.Type: ApplicationFiled: November 14, 2016Publication date: July 13, 2017Inventors: Steve Cooper, Neal Andrews, Maura Mahon, Rachel Dreilinger, David Barsic, Weston Myler, Martin Krauss, Scot Herbst, James Ingle, Gerald Thomas, Rich Myers, Brian Young, Juven Lara, Charles Noll
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Patent number: 9546930Abstract: An analysis cartridge the includes a main body portion and a filter assembly. The main body portion includes an upper portion that defines an upper chamber and a lower portion that defines a fluid chamber. The filter assembly is movable along a filter assembly path between a first position and a second position. The filter assembly has an opening defined therethrough. In the first position, the opening partially defines the upper chamber and in the second position the opening partially defines the fluid chamber.Type: GrantFiled: June 29, 2015Date of Patent: January 17, 2017Assignee: PULSE HEATH LLCInventors: Martin Krauss, Maura Mahon, Andrew E. King, Steve Cooper, James Ingle, Gerald Thomas, David Barsic, Neal Andrews, Brian Young, Juven Lara, Charles Noll
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Publication number: 20160370378Abstract: Fluorescence chromophores such as phenylene diamine derivatives can undergo oxidative coupling and polymerization to form optical, colorimetric and fluorogenic, multimers and polymers. The presence of carbonyl containing moieties such as aldehydes and ketones under favorable environmental conditions can initiate, catalyze, accelerate and modulate this reaction which in turn provides a mechanism for the detection and quantitation of such moieties. Selected phenylene diamine derivatives can be used for the detection and quantitation of aldehyde and ketones via measurement of the reaction and the associated spectroscopic transformation. In particular, the use of meta-phenylene diamine (rnPDA) and related compounds for aldehyde detection and quantitation is described. The method provides a convenient means for monitoring aldehyde and ketone levels without use of separation steps. The method is applicable to kinetic and quasi-endpoint detection assay formats.Type: ApplicationFiled: July 29, 2016Publication date: December 22, 2016Inventors: Gerald THOMAS, Brian YOUNG, Juven LARA, Charles NOLL, James INGLE
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Patent number: 9494495Abstract: A breath analysis system that includes a handle assembly with an analysis cartridge on an upper end thereof. The handle includes a main body portion with a pressure opening and a pressure transducer therein. The analysis cartridge includes a main body portion with an upper portion that defines a breath chamber, a lower portion that defines a fluid chamber and a filter assembly that is movable between a breath capture position and an analysis position. The filter assembly has an opening defined therethrough. In the breath capture position, the opening partially defines the breath chamber and in the analysis position the opening partially defines the fluid chamber. The system also includes an analysis device with a case, a door, a controller that controls the motor and a fluorescence detection assembly and a rotation assembly positioned in the case interior. The rotation assembly includes a shroud with a funnel portion for receiving the analysis cartridge.Type: GrantFiled: June 29, 2015Date of Patent: November 15, 2016Assignee: PULSE HEALTH LLCInventors: Steve Cooper, Neal Andrews, Maura Mahon, Rachel Dreilinger, David Barsic, Weston Myler, Martin Krauss, Scot Herbst, James Ingle, Gerald Thomas, Rick Myers, Brian Young, Juven Lara, Charles Noll
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Patent number: 9404836Abstract: Fluorescence chromophores such as phenylene diamine derivatives can undergo oxidative coupling and polymerization to form optical, colorimetric and fluorogenic, multimers and polymers. The presence of carbonyl containing moieties such as aldehydes and ketones under favorable environmental conditions can initiate, catalyze, accelerate and modulate this reaction which in turn provides a mechanism for the detection and quantitation of such moieties. Selected phenylene diamine derivatives can be used for the detection and quantitation of aldehyde and ketones via measurement of the reaction and the associated spectroscopic transformation. In particular, the use of meta-phenylene diamine (mPDA) and related compounds for aldehyde detection and quantitation is described. The method provides a convenient means for monitoring aldehyde and ketone levels without use of separation steps. The method is applicable to kinetic and quasi-endpoint detection assay formats.Type: GrantFiled: June 29, 2015Date of Patent: August 2, 2016Assignee: Pulse Health LLCInventors: Gerald Thomas, Brian Young, Juven Lara, Charles Noll, James Ingle
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Publication number: 20150377858Abstract: Fluorescence chromophores such as phenylene diamine derivatives can undergo oxidative coupling and polymerization to form optical, colorimetric and fluorogenic, multimers and polymers. The presence of carbonyl containing moieties such as aldehydes and ketones under favorable environmental conditions can initiate, catalyze, accelerate and modulate this reaction which in turn provides a mechanism for the detection and quantitation of such moieties. Selected phenylene diamine derivatives can be used for the detection and quantitation of aldehyde and ketones via measurement of the reaction and the associated spectroscopic transformation. In particular, the use of meta-phenylene diamine (mPDA) and related compounds for aldehyde detection and quantitation is described. The method provides a convenient means for monitoring aldehyde and ketone levels without use of separation steps. The method is applicable to kinetic and quasi-endpoint detection assay formats.Type: ApplicationFiled: June 29, 2015Publication date: December 31, 2015Inventors: Gerald Thomas, Brian Young, Juven Lara, Charles Noll, James Ingle
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Publication number: 20150377859Abstract: An analysis cartridge the includes a main body portion and a filter assembly. The main body portion includes an upper portion that defines an upper chamber and a lower portion that defines a fluid chamber. The filter assembly is movable along a filter assembly path between a first position and a second position. The filter assembly has an opening defined therethrough. In the first position, the opening partially defines the upper chamber and in the second position the opening partially defines the fluid chamber.Type: ApplicationFiled: June 29, 2015Publication date: December 31, 2015Inventors: Martin Krauss, Maura Mahon, Adrew E. King, Steve Cooper, James Ingle, Gerald Thomas, David Barsic, Neal Andrews, Brian Young, Juven Lara, Charles Noll
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Publication number: 20150377748Abstract: A breath analysis system that includes a handle assembly with an analysis cartridge on an upper end thereof. The handle includes a main body portion with a pressure opening and a pressure transducer therein. The analysis cartridge includes a main body portion with an upper portion that defines a breath chamber, a lower portion that defines a fluid chamber and a filter assembly that is movable between a breath capture position and an analysis position. The filter assembly has an opening defined therethrough. In the breath capture position, the opening partially defines the breath chamber and in the analysis position the opening partially defines the fluid chamber. The system also includes an analysis device with a case, a door, a controller that controls the motor and a fluorescence detection assembly and a rotation assembly positioned in the case interior. The rotation assembly includes a shroud with a funnel portion for receiving the analysis cartridge.Type: ApplicationFiled: June 29, 2015Publication date: December 31, 2015Inventors: Steve Cooper, Neal Andrews, Martin Krauss, Andrew E. King, Maura Mahon, Weston Myler, James Ingle, Gerald Thomas, Rachel Dreilinger, David Barsic, Rick Myers, Craig Carlsen, Scot Herbst, Brian Young, Juven Lara, Charles Noll
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Publication number: 20150377868Abstract: A breath analysis system that includes a handle assembly with an analysis cartridge on an upper end thereof. The handle includes a main body portion with a pressure opening and a pressure transducer therein. The analysis cartridge includes a main body portion with an upper portion that defines a breath chamber, a lower portion that defines a fluid chamber and a filter assembly that is movable between a breath capture position and an analysis position. The filter assembly has an opening defined therethrough. In the breath capture position, the opening partially defines the breath chamber and in the analysis position the opening partially defines the fluid chamber. The system also includes an analysis device with a case, a door, a controller that controls the motor and a fluorescence detection assembly and a rotation assembly positioned in the case interior. The rotation assembly includes a shroud with a funnel portion for receiving the analysis cartridge.Type: ApplicationFiled: June 29, 2015Publication date: December 31, 2015Inventors: Steve Cooper, Neal Andrews, Maura Mahon, Rachel Dreilinger, David Barsic, Weston Myler, Martin Krauss, Scot Herbst, James Ingle, Gerald Thomas, Rick Myers, Brian Young, Juven Lara, Charles Noll