Patents by Inventor Juyan Liu

Juyan Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • spore oil and use thereof in preparation of anti-cancer-related fatigue medicaments
    Patent number: 12622939
    Abstract: Ganoderma lucidum spore oil and use thereof in the preparation of anti-cancer-related fatigue medicaments are provided. The content of triglycerides in the Ganoderma lucidum spore oil is greater than 90%. Ganoderma lucidum triterpenoids are not detected. The Ganoderma lucidum spore oil is extracted by means of supercritical CO2, eluted with a silica gel column and a mixed solution of petroleum ether-ethyl acetate, concentrated under reduced pressure and vacuum-dried. The Ganoderma lucidum spore oil is highly effective in mitigating cancer-related fatigue, has good safety, and can be used in the preparation of medicaments for treating cancer-related fatigue.
    Type: Grant
    Filed: January 17, 2024
    Date of Patent: May 12, 2026
    Assignee: GUANGZHOU HANFANG PHARMACEUTICAL CO., LTD.
    Inventors: Juyan Liu, Wendong Xu, Hongfei Cai, Jing Li, Cheng Yuan, Yaming Han, Lin Cao, Shunzhi Tang, Yukang Mao, Guocai Wang, Qin Zhang
  • PREPARATION METHOD OF PAEONIFLORIN-6'-O-BENZENE SULFONATE
    Publication number: 20240270781
    Abstract: Provided in the present disclosure is a preparation method of paeoniflorin-6?-O-benzene sulfonate. The method uses crude paeoniflorin instead of paeoniflorin as a raw material, which more complies with actual requirements of an industrial production process of paeoniflorin-6?-O-benzene sulfonate, and uses an organometallic catalyst, an acid-binding agent and chemically active benzenesulfonyl chloride to react with paeoniflorin. Compared with the prior art, the method significantly increases the yield of crude paeoniflorin-6?-O-benzene sulfonate which is separated and purified by means of column chromatography and then refined to obtain paeoniflorin-6?-O-benzenesulfonate with a content of at least 98%, thereby realizing industrial production of the paeoniflorin-6?-O-benzene sulfonate.
    Type: Application
    Filed: October 19, 2021
    Publication date: August 15, 2024
    Inventors: Wendong XU, Cheng YUAN, Shunzhi TANG, Juyan LIU, Hongfei CAI, Bai BAI, Jing LI, Yuping FU, Songtao LI, Wancai PENG, Yonghua LI, Yao LI, Jirong LI, Shaoheng WEI, Jiali LI
  • GANODERMA LUCIDUM SPORE OIL AND USE THEREOF IN PREPARATION OF ANTI-CANCER-RELATED FATIGUE MEDICAMENTS
    Publication number: 20240197799
    Abstract: Ganoderma lucidum spore oil and use thereof in the preparation of anti-cancer-related fatigue medicaments are provided. The content of triglycerides in the Ganoderma lucidum spore oil is greater than 90%. Ganoderma lucidum triterpenoids are not detected. The Ganoderma lucidum spore oil is extracted by means of supercritical CO2, eluted with a silica gel column and a mixed solution of petroleum ether-ethyl acetate, concentrated under reduced pressure and vacuum-dried. The Ganoderma lucidum spore oil is highly effective in mitigating cancer-related fatigue, has good safety, and can be used in the preparation of medicaments for treating cancer-related fatigue.
    Type: Application
    Filed: January 17, 2024
    Publication date: June 20, 2024
    Inventors: Juyan Liu, Wendong Xu, Hongfei Cai, Jing Li, Cheng Yuan, Yaming Han, Lin Cao, Shunzhi Tang, Yukang Mao, Guocai Wang, Qin Zhang