Abstract: The present invention relates to a method for preparing a core-gap-shell nanoparticle having an average height of 0.1 nm to 10 nm, in which a Raman-active material is disposed between a core and a shell, and more specifically, to a method for preparing a core-gap-shell nanoparticle, which comprises introducing a shell made of an alloy of a second metal and a third metal, on the core particles of the first metal, the surface of which is modified with a Raman-active material; selectively removing the second metal by treating with a second metal etchant, followed by dealloying; the core-gap-shell nanoparticle prepared by the above method comprising a Raman-active material disposed in the gap, and uses of the core-gap-shell nanoparticle for biosensing and/or bioimaging.

Abstract: A lipid nanotablet according to the present disclosure includes: a supported lipid bilayer having a plurality of nanoparticles integrated in nanoparticle units; an immobile nano-receptor including at least one first surface molecule from among the plurality of nanoparticles and coupled to the surface of the nano-receptor, and a mobile nano-floater including at least one second surface molecule from among the plurality of nanoparticles coupled to the surface of the nano-floater. Interaction between the nano-receptor and the nano-floater is controlled according to the result of a reaction to an input by the at least one first surface molecule and the at least one second surface molecule, and the lipid nanotablet provides a logic result on the basis of the interaction.

Abstract: Provided is a nanoparticle including: a core structure; and a shell structure covering the core structure and separated from the core structure by a nanogap, wherein a macrocyclic host molecule exhibiting hydrophobicity inside and hydrophilicity outside and a Raman-active material inserted into the macrocyclic host molecule are provided on a surface of the core structure, and the macrocyclic host molecule and the Raman-active material fill the nanogap.

Abstract: The present invention relates to a method for detecting a target analyte using a gold nanoparticle, comprising growing a copper crystal specifically on a gold nanoparticle by treating the gold nanoparticle with a solution comprising a copper ion, a polymer having a primary or secondary amine group, and a reducing agent, a composition for amplifying a signal used in the detection method above, and a kit for detecting a target analyte comprising the composition for amplifying a signal above.

Abstract: Provided are: an array, a kit, and/or a device which are for analyzing, identifying, detecting, and/or visualizing target particles, and/or determining the presence or absence of the target particles, and use a substrate having an uneven surface coated with a lipid bilayer; and a method using same.

Abstract: A nanostructure including a metal core, a metal shell surrounding the metal core, and a dielectric layer disposed between the metal core and the metal shell and including a quantum dot, a composite including the nanostructure, a display panel including the composite, and an electronic device including the display panel.

Abstract: A nano computing device includes: a nanoparticle memory including a first molecule bound so as to store a molecular input; a nanoparticle reporter including a second molecule bound so as to generate an output; and a nanoparticle floater including at least two third molecules and fourth molecules so as to be bound to one of the nanoparticle memory and the nanoparticle reporter based on the molecular input and an instruction molecule.

Abstract: The present invention relates to a core-shell nanocomposite including fluorescent bodies disposed to have a uniform distance in a perpendicular direction from a surface thereof, to a method of manufacturing same, and to a use for a probe for metal-enhanced fluorescence.

Abstract: The present invention relates to a method for preparing a metal nanocube with a controlled corner sharpness index, comprising a step of reacting with a first surfactant and a predetermined surface-protecting agent; a method for preparing a metal nanocube aggregate having a purity of 95% or more, comprising a step of centrifuging in the presence of a second surfactant; a probe composition comprising the metal nanocube or metal nanocube aggregate prepared by the method; and a gold (Au) nanocube having an average edge length of 20 nm or less.

Abstract: The present invention relates to a method for preparing a core-gap-shell nanoparticle having an average height of 0.1 nm to 10 nm, in which a Raman-active material is disposed between a core and a shell, and more specifically, to a method for preparing a core-gap-shell nanoparticle, which comprises introducing a shell made of an alloy of a second metal and a third metal, on the core particles of the first metal, the surface of which is modified with a Raman-active material; selectively removing the second metal by treating with a second metal etchant, followed by dealloying; the core-gap-shell nanoparticle prepared by the above method comprising a Raman-active material disposed in the gap, and uses of the core-gap-shell nanoparticle for biosensing and/or bioimaging.

Abstract: A nanoparticle heterodimer in which Raman-active molecules are located at a binding portion of the nanoparticle heterodimer is disclosed. A core-shell nanoparticle heterodimer includes a gold or silver core having a surface to which oligo nucleotides are bonded; and a gold or silver shell covering the core. In addition, a core-shell nanoparticle dimer, a method for preparing same, and uses thereof are disclosed.

Abstract: The present invention relates to a method for detecting a target analyte using a gold nanoparticle, comprising growing a copper crystal specifically on a gold nanoparticle by treating the gold nanoparticle with a solution comprising a copper ion, a polymer having a primary or secondary amine group, and a reducing agent, a composition for amplifying a signal used in the detection method above, and a kit for detecting a target analyte comprising the composition for amplifying a signal above.

Abstract: Disclosed herein are an artificial cell membrane including a supported lipid bilayer (SLB) including a substrate and mobility-decreased metal particles bonded onto the substrate; an analysis device or kit including the artificial cell membrane and examining the interactions between molecules, in which one molecule is bonded to the surface of a mobility-decreased metal particle bonded to the artificial cell membrane and the other molecule is bonded to the surface of a mobility-increased metal particle bonded to a lipid at a low valency; a method of examining the interactions between molecules using the analysis device; a kit for quantitative or qualitative analysis of a target material including the artificial cell membrane by plasmonic scattering measurements; and a multiple analysis kit capable of detecting a plurality of target materials using a plurality of metal particles having different plasmonic scattering wavelengths and/or having mobility on a supported lipid bilayer.

Abstract: The present invention relates to nanoparticles in the shape of nanosnowman with a head part and a body part, a preparation method thereof, and a detection method using the same. More particularly, the present invention relates to nanoparticles in the shape of nanosnowman with head and body parts, which can offer platforms for DNA-based assembly of various aligned and unconventional nanostructures and is highly applicable to the detection of DNA and an analyte associated, with the onset and progression of a particular disease, a preparation method thereof, and a detection method using the same.

Abstract: The present invention relates to a core-shell nanocomposite including fluorescent bodies disposed to have a uniform distance in a perpendicular direction from a surface thereof, to a method of manufacturing same, and to a use for a probe for metal-enhanced fluorescence.

Abstract: The present invention relates to a nanoparticle heterodimer in which Raman-active molecules are located at a binding portion of the nanoparticle heterodimer, and more particularly, to a core-shell nanoparticle heterodimer comprising: a gold or silver core having a surface to which oligonucleotides are bonded; and a gold or silver shell covering the core. In addition, the present invention relates to the core-shell nanoparticle dimer, to a method for preparing same, and to the use thereof.

Abstract: Disclosed herein are an artificial cell membrane including a supported lipid bilayer (SLB) including a substrate and mobility-decreased metal particles bonded onto the substrate; an analysis device or kit including the artificial cell membrane and examining the interactions between molecules, in which one molecule is bonded to the surface of a mobility-decreased metal particle bonded to the artificial cell membrane and the other molecule is bonded to the surface of a mobility-increased metal particle bonded to a lipid at a low valency; a method of examining the interactions between molecules using the analysis device; a kit for quantitative or qualitative analysis of a target material including the artificial cell membrane by plasmonic scattering measurements; and a multiple analysis kit capable of detecting a plurality of target materials using a plurality of metal particles having different plasmonic scattering wavelengths and/or having mobility on a supported lipid bilayer.

Abstract: The present invention relates to nanoparticles in the shape of nanosnowman with a head part and a body part, a preparation method thereof, and a detection method using the same. More particularly, the present invention relates to nanoparticles in the shape of nanosnowman with head and body parts, which can offer platforms for DNA-based assembly of various aligned and unconventional nanostructures and is highly applicable to the detection of DNA and an analyte associated, with the onset and progression of a particular disease, a preparation method thereof, and a detection method using the same.

Abstract: The present invention is to provide a nanoparticle, which can be used effectively for Raman analysis based on very high amplification effect of electromagnetic signal by plasomonic coupling of nanogap formation inside thereof and high reproducibility, and which includes core and surrounding shell with nanogap formation between the same and the method of synthesis thereof. The present invention is also to provide the method for detecting the analyte using the above nanoparticle and the analyte detection kit including the above nanoparticle.

Abstract: The present invention relates to a nanoparticle heterodimer in which Raman-active molecules are located at a binding portion of the nanoparticle heterodimer, and more particularly, to a core-shell nanoparticle heterodimer comprising: a gold or silver core having a surface to which oligonucleotides are bonded; and a gold or silver shell covering the core. In addition, the present invention relates to the core-shell nanoparticle dimer, to a method for preparing same, and to the use thereof.