Patents by Inventor Jwu-Sheng Tung

Jwu-Sheng Tung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Large scale affinity chromatography of macromolecules
    Patent number: 6372425
    Abstract: A process of purifying target molecules is described that involves the selection of ligands based on identifying, in real time, association and dissociation constants with a given target molecule; using this information to select at least one ligand that exhibit predetermined association and dissociation constants with a given target molecule; anchoring a quantity of ligand to an activated solid support; contacting a quantity of target molecules with the anchored ligand(s); removing low affinity target molecules from anchored ligand and eluting particularly pure target molecules.
    Type: Grant
    Filed: August 21, 1998
    Date of Patent: April 16, 2002
    Assignee: Merck & Co., Inc.
    Inventors: Beth Arnold, Paul M. Keller, Anthony J. Conley, Alan R. Shaw, Jwu-Sheng Tung
  • Antistasin derived anticoagulant protein
    Patent number: 5189019
    Abstract: A protein having a molecular weight of about 6,000 daltons which is biologically active in the inhibition of Factor Xa during the blood coagulation cascade, a method for producing the protein, methods for inhibiting blood coagulation using the protein, and suitable pharmaceutical compositions.
    Type: Grant
    Filed: April 23, 1990
    Date of Patent: February 23, 1993
    Assignee: Merck & Co., Inc.
    Inventors: Linda O. Palladino, Melvin Silberklang, Jwu-Sheng Tung, Simon W. Law, George E. Mark