Patents by Inventor Jyh-Horng Sheu

Jyh-Horng Sheu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating or preventing the visual function loss by using 4-(phenylsulfanyl)butane-2-one (4-PSB-2)
    Patent number: 9907763
    Abstract: The present invention relates to a method of treating or preventing the visual function loss in optic nerve in a subject after crush injury by using 4-(Phenylsulfanyl)butane-2-one (4-PSB-2). The present invention has the ability of enhancing the protection effect of RGCs, preserving the visual function in optic nerve after crush injury, recovering the visual function loss, attenuating apoptosis in optic nerve after injury, and inhibiting the inflammatory responses in optic nerves after ON injury.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: March 6, 2018
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Shun-Ping Huang, Jyh-Horng Sheu, Zhi-Hong Wen, Rong-Kung Tsai
  • METHOD OF TREATING OR PREVENTING THE VISUAL FUNCTION LOSS BY USING 4-(PHENYLSULFANYL)BUTANE-2-ONE (4-PSB-2)
    Publication number: 20170304219
    Abstract: The present invention relates to a method of treating or preventing the visual function loss in optic nerve in a subject after crush injury by using 4-(Phenylsulfanyl)butane-2-one (4-PSB-2). The present invention has the ability of enhancing the protection effect of RGCs, preserving the visual function in optic nerve after crush injury, recovering the visual function loss, attenuating apoptosis in optic nerve after injury, and inhibiting the inflammatory responses in optic nerves after ON injury.
    Type: Application
    Filed: October 21, 2016
    Publication date: October 26, 2017
    Applicants: NATIONAL SUN YAT-SEN UNIVERSITY, TZU-CHI UNIVERSITY
    Inventors: SHUN-PING HUANG, JYH-HORNG SHEU, ZHI-HONG WEN, RONG-KUNG TSAI
  • Pharmaceutical uses of sulfur-containing compound
    Patent number: 9238620
    Abstract: The invention relates to uses of the sulfur-containing compound in inhibiting activities of a factor related to cancer metastasis and/or growth. Preferably, the invention relates to uses of the sulfur-containing compound in inhibiting lung cancer metastasis and/or growth.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: January 19, 2016
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Chieh-Hsi Wu, Jyh-Horng Sheu, Chih-Yi Chen, Yi-Chung Chien, Shuo-Chueh Chen, Chun-Hsu Pan, Chiung-Yao Huang
  • PHARMACEUTICAL USES OF SULFUR-CONTAINING COMPOUND
    Publication number: 20160009642
    Abstract: The invention relates to uses of the sulfur-containing compound in inhibiting activities of a factor related to cancer metastasis and/or growth. Preferably, the invention relates to uses of the sulfur-containing compound in inhibiting lung cancer metastasis and/or growth.
    Type: Application
    Filed: July 9, 2014
    Publication date: January 14, 2016
    Inventors: CHIEH-HSI WU, JYH-HORNG SHEU, CHIH-YI CHEN, YI-CHUNG CHIEN, SHUO-CHUEH CHEN, CHUN-HSU PAN, CHIUNG-YAO HUANG
  • Compounds from soft coral, method of preparation and pharmaceutical uses thereof
    Patent number: 8927594
    Abstract: The invention relates to compounds from the soft coral and the generation thereof. The invention also relates to the uses of the compounds from the soft coral in inhibiting inducible nitric oxide synthase and/or cyclooxygenase-2 and in treating the diseases associated with inducible nitric oxide synthase and/or cyclooxygenase-2.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: January 6, 2015
    Assignees: National Sun Yat-Sen University, National Museum of Marine Biology & Aquarium
    Inventors: Jyh-Horng Sheu, Wei-Hsien Wang, Zhi-Hong Wen, Bo-Wei Chen, Ping-Jyun Sung
  • Sulfur-containing compound, method of preparation and pharmaceutical uses thereof
    Patent number: 8722745
    Abstract: The invention relates to a sulfur-containing compound and the preparation thereof. The invention also relates to the uses of the sulfur-containing compound in inhibiting inducible nitric oxide synthase and/or cyclooxygenase-2 and in treating the diseases associated with inducible nitric oxide synthase and/or cyclooxygenase-2. This invention also describes a series of chemical analogues of the said sulfur-containing compound and the preparation of these compounds.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: May 13, 2014
    Assignee: National Sun Yat-Sen University
    Inventors: Jyh-Horng Sheu, Chih-Hua Chao, Zhi-Hong Wen
  • Pharmaceutical uses of diterpene excavatolide B from a coral or an analogue thereof
    Patent number: 8530513
    Abstract: The invention relates to use of a diterpene from a coral, excavatolide B, or an analogue thereof for treating a disease associated with inducible nitric oxide synthase, cyclooxygenase-2 and/or matrix metalloproteinase. The invention also relates to use of a diterpene from a coral, excavatolide B, and an analogue thereof for treating a disease associated with TNF-? and/or IL-6 over-expression.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: September 10, 2013
    Assignee: National Sun Yat-Sen University
    Inventors: Jyh-Horng Sheu, Ning-Sun Yang, Wen-Chi Wei, Chiung-Yao Huang
  • Sulfur-containing compound, method of preparation and pharmaceutical uses thereof
    Patent number: 8399661
    Abstract: The invention relates to a sulfur-containing compound and the preparation thereof. The invention also relates to the uses of the sulfur-containing compound in inhibiting inducible nitric oxide synthase and/or cyclooxygenase-2 and in treating the diseases associated with inducible nitric oxide synthase and/or cyclooxygenase-2. This invention also describes a series of chemical analogues of the said sulfur-containing compound and the preparation of these compounds.
    Type: Grant
    Filed: July 14, 2008
    Date of Patent: March 19, 2013
    Assignee: National Sun Yat-Sen University
    Inventors: Jyh-Horng Sheu, Chih-Hua Chao, Zhi-Hong Wen
  • COMPOUNDS FROM SOFT CORAL, METHOD OF PREPARATION AND PHARMACEUTICAL USES THEREOF
    Publication number: 20120071547
    Abstract: The invention relates to compounds from the soft coral and the generation thereof. The invention also relates to the uses of the compounds from the soft coral in inhibiting inducible nitric oxide synthase and/or cyclooxygenase-2 and in treating the diseases associated with inducible nitric oxide synthase and/or cyclooxygenase-2.
    Type: Application
    Filed: March 15, 2011
    Publication date: March 22, 2012
    Applicants: NATIONAL MUSEUM OF MARINE BIOLOGY & AQUARIUM, NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: JYH-HORNG SHEU, WEI-HSIEN WANG, ZHI-HONG WEN, BO-WEI CHEN, PING-JYUN SUNG
  • SULFUR-CONTAINING COMPOUND, METHOD OF PREPARATION AND PHARMACEUTICAL USES THEREOF
    Publication number: 20090062285
    Abstract: The invention relates to a sulfur-containing compound and the preparation thereof. The invention also relates to the uses of the sulfur-containing compound in inhibiting inducible nitric oxide synthase and/or cyclooxygenase-2 and in treating the diseases associated with inducible nitric oxide synthase and/or cyclooxygenase-2. This invention also describes a series of chemical analogues of the said sulfur-containing compound and the preparation of these compounds.
    Type: Application
    Filed: July 14, 2008
    Publication date: March 5, 2009
    Applicant: National Sun Yat-Sen University
    Inventors: Jyh-Horng Sheu, Chih-Hua Chao, Zhi-Hong Wen