Patents by Inventor Jyoti K. Jaiswal

Jyoti K. Jaiswal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF RECOMBINANT HUMAN ACID SPHINGOMYELINASE TO IMPROVE SKELETAL MYOFIBER REPAIR
    Publication number: 20230226221
    Abstract: Compositions and methods for the treatment of muscular dystrophies are provided.
    Type: Application
    Filed: June 29, 2021
    Publication date: July 20, 2023
    Inventors: Jyoti K. Jaiswal, Aurelia Defour, Daniel Bittel, Goutam Chandra, Sreetama Sen Chandra
  • Prussian blue-inspired constructs for multimodal imaging and therapy
    Patent number: 9987378
    Abstract: The invention describes a coordination polymer construct for multimodal imaging and therapy. The construct consists of a core particle made of a novel coordination polymer. The core is coated with a biocompatible coating that stabilizes the particles in a physiological environment. The biocompatible coating can contain attached targeting agents, imaging agents and therapeutic agents or combinations one or more of the targeting, imaging and therapeutic agents. When administered to a subject or a subject-derived specimen, the resulting coordination polymer core-shell construct enables multimodal imaging and therapy, which improves the diagnostic and treatment outcomes of the conditions or diseases where it is administered. The invention describes the novel material, base for the construct, methods for the preparation of the said construct and its use as a multimodal imaging and therapy agent.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: June 5, 2018
    Assignee: Children's National Medical Center
    Inventors: Rohan Fernandes, Matthieu F. Dumont, Raymond W. Sze, Laurie S. Conklin, Hilary A. Hoffman, Jyoti K. Jaiswal
  • Prussian blue-inspired constructs for multimodal imaging and therapy
    Patent number: 9561183
    Abstract: The invention describes a coordination polymer construct for multimodal imaging and therapy. The construct consists of a core particle made of a novel coordination polymer. The core is coated with a biocompatible coating that stabilizes the particles in a physiological environment. The biocompatible coating can contain attached targeting agents, imaging agents and therapeutic agents or combinations one or more of the targeting, imaging and therapeutic agents. When administered to a subject or a subject-derived specimen, the resulting coordination polymer core-shell construct enables multimodal imaging and therapy, which improves the diagnostic and treatment outcomes of the conditions or diseases where it is administered. The invention describes the novel material, base for the construct, methods for the preparation of the said construct and its use as a multimodal imaging and therapy agent.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: February 7, 2017
    Assignee: Children's National Medical Center
    Inventors: Rohan Fernandes, Matthieu F. Dumont, Raymond W. Sze, Laurie S. Conklin, Hilary A. Hoffman, Jyoti K. Jaiswal