Abstract: A modular valve assembly provides an airtight, shockproof, leakproof and evaporation proof closure effective for sealing engagement with the neck or outlet of a flexible or reducible container. The modular valve assembly is effective in preventing: (1) leakage of fluids from the container due to vibration or changes in temperature or pressure; (2) any backflow or reentry of contaminants through the valve assembly, including air; and (3) evaporation of fluid from the container. If the fluid initially is sterile, the closure maintains the sterility of the remaining fluid in the container during and between dispensings of the fluid. Thus, the modular valve assembly extends the useful life of the fluid in the container to its shelf life. Although the user makes many dispensings from it, the container behaves as though she or he had never opened it. Thermostable fluids delivered through this modular valve assembly have no need for preservatives or refrigeration.

Abstract: A modular valve assembly provides an airtight, shockproof, leakproof and evaporation proof closure effective for sealing engagement with the neck or outlet of a flexible or reducible container. The modular valve assembly is effective in preventing: (1) leakage of fluids from the container due to vibration or changes in temperature or pressure; (2) any backflow or reentry of contaminants through the valve assembly, including air; and (3) evaporation of fluid from the container. If the fluid initially is sterile, the closure maintains the sterility of the remaining fluid in the container during and between dispensings of the fluid. Thus, the modular valve assembly extends the useful life of the fluid in the container to its shelf life. Although the user makes many dispensings from it, the container behaves as though she or he had never opened it. Thermostable fluids delivered through this modular valve assembly have no need for preservatives or refrigeration.

Abstract: A modular cap delivery system comprising an elastomeric seal and conformably engaging seat can be affixed to or integrated in the neck of a container such as a bottle, flexible bag, tube, or any container having a neck and holding a quantity of a flowable medium. The configuration of the seal and seat eliminate the influx of air, airborne pathogens, or any contaminant into the container of flowable medium to which the delivery device is attached, thereby maintaining the integrity and sterility of a flowable material, even when challenged by direct contact through immersion in suspensions of bacteria or viruses. The delivery device is highly scalable in size, can work for viscous fluids that are difficult to flow, and enables a flowable material to be reformulated without preservatives or antioxidants. This provides the advantage of an enhanced therapeutic effect for many medications, particularly eye care solutions.