Abstract: This specification relates to a process for preparing a purified human milk oligosaccharide (“HMO”) from an HMO-containing solution (e.g., a fermentation broth) by a process comprising mixed bed ion exchange, and a product of such a process.

Abstract: This specification relates to a process for preparing a purified human milk oligosaccharide (“HMO”) from an HMO-containing solution (e.g., a fermentation broth) by a process comprising removal of an antifoam agent, and a product of such a process.

Abstract: Compositions comprising mevalonolactone, mevalonic add, mevalonate, salts of mevalonic acid, mevalonolactone monohydrate, or any combination thereof and methods of use are provided for topical application for skin care, skin supplement, hair care, and oral care. More specifically, the present disclosure is directed towards compositions comprising mevalonolactone, mevalonic acid, mevalonate, salts of mevalonic acid, mevalonolactone monohydrate, or any combination thereof for providing a skin care benefit and/or multiple skin care benefits.

Abstract: Compositions and methods are provided for producing crystalline forms of organic acids or salts or lactones thereof from an aqueous solution. More specifically, methods are provided for producing a crystalline form of a salt of mevalonic acid (also referred to as X-MVA) from an aqueous solution, comprising subjecting the aqueous solution comprising said X-MVA to a purification step to produce a purified solution and crystallizing said X-MVA from said purified solution by water solvent crystallization. Methods are also provided for producing mevalonolactone from an aqueous solution comprising X-MVA, comprising subjecting the aqueous solution comprising said X-MVA to cation exchange thereby converting said aqueous solution comprising X-MVA to an aqueous solution comprising mevalonolactone (MVL). Methods are also provided for producing mevalonolactone monohydrate crystals.

Abstract: Disclosed herein are aqueous compositions comprising fructose and methods of production thereof. A method for producing an aqueous composition comprising fructose can comprise, for example, conducting an enzymatic reaction by contacting water, sucrose, and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan having at least 30% alpha-1,3-linkages. A soluble fraction produced by such a reaction comprises at least about 55% fructose on a dry weight basis, and can be separated from insoluble poly alpha-1,3-glucan product(s), thereby providing an aqueous composition comprising fructose.

Abstract: This specification relates to a process for preparing fucose from a human milk oligosaccharide (“HMO”) comprising a fucose moiety, as well as L-fucose compositions prepared by such a process.

Abstract: Disclosed herein are aqueous compositions comprising fructose and methods of production thereof. A method for producing an aqueous composition comprising fructose can comprise, for example, conducting an enzymatic reaction by contacting water, sucrose, and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan having at least 30% alpha-1,3-linkages. A soluble fraction produced by such a reaction comprises at least about 55% fructose on a dry weight basis, and can be separated from insoluble poly alpha-1,3-glucan product(s), thereby providing an aqueous composition comprising fructose.

Abstract: Disclosed herein are aqueous compositions comprising fructose and methods of production thereof. A method for producing an aqueous composition comprising fructose can comprise, for example, conducting an enzymatic reaction by contacting water, sucrose, and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan having at least 30% alpha-1,3-linkages. A soluble fraction produced by such a reaction comprises at least about 55% fructose on a dry weight basis, and can be separated from insoluble poly alpha-1,3-glucan product(s), thereby providing an aqueous composition comprising fructose.

Abstract: Disclosed herein are aqueous compositions comprising fructose and methods of production thereof. A method for producing an aqueous composition comprising fructose can comprise, for example, conducting an enzymatic reaction by contacting water, sucrose, and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan having at least 30% alpha-1,3-linkages. A soluble fraction produced by such a reaction comprises at least about 55% fructose on a dry weight basis, and can be separated from insoluble poly alpha-1,3-glucan product(s), thereby providing an aqueous composition comprising fructose.

Abstract: The invention relates to an improved process for the production of a sugar alcohol from the corresponding sugar through catalytic hydrogenation. Especially, the invention relates to a process for reducing the interference of sugar-derived aldonic acids in the hydrogenation process by adjusting the hydrogenation conditions so that the activity of the catalyst is maintained. In one embodiment of the invention, the process of the invention is carried out by adjusting the hydrogenation temperature by starting the hydrogenation at a lower temperature and then gradually rising the temperature to the final hydrogenation temperature. In another embodiment of the invention, the process of the invention is carried out by adding small-molecular monocarboxylic acids to the hydrogenation solution.

Abstract: The invention relates to an improved process for the production of a sugar alcohol from the corresponding sugar through catalytic hydrogenation. Especially, the invention relates to a process for reducing the interference of sugar-derived aldonic acids in the hydrogenation process by adjusting the hydrogenation conditions so that the activity of the catalyst is maintained. In one embodiment of the invention, the process of the invention is carried out by adjusting the hydrogenation temperature by starting the hydrogenation at a lower temperature and then gradually rising the temperature to the final hydrogenation temperature. In another embodiment of the invention, the process of the invention is carried out by adding small-molecular monocarboxylic acids to the hydrogenation solution.