Patents by Inventor Jyun-Han Ka

Jyun-Han Ka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FOLIC ACID-MEDIATED MAGNETIC NANOPARTICLE CLUSTERS FOR COMBINED TARGETING, DIAGNOSIS, AND THERAPY APPLICATIONS
    Publication number: 20110085987
    Abstract: The preparation method of the magnetic nanoparticle (MNP) includes steps of: (a) reacting folic acid (FA) with Pluronic F127 (PF127) to form FA-PF127; (b) reacting poly(acrylic acid) (PAA) with FeCl3 to form PAA-bound iron oxide (PAAIO); and (c) reacting FA-PF127 with PAAIO via N-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDAC) mediation to form FA-PF127-PAAIO. FA-PF127-PAAIO is nontoxic and shows the superparamagnetic property at room temperature. The Nile red-loaded FA-PF127-PAAIO can be performed as the chemotherapy agent and the contrast agent on magnetic resonance (MR) imaging.
    Type: Application
    Filed: January 27, 2010
    Publication date: April 14, 2011
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Li-Fang Wang, Jia-Jyun Lin, Jenn-Shing Chen, Shih-Jer Huang, Jyun-Han Ka, Yun-Ming Wang, Ting-Jung Chen