Patents by Inventor Jyun-Liang LIN

Jyun-Liang LIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Base editing enzymes
    Patent number: 12286654
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Grant
    Filed: June 15, 2022
    Date of Patent: April 29, 2025
    Assignee: Metagenomi, Inc.
    Inventors: Jyun-Liang Lin, Alan Brooks, Cristina Butterfield, Christopher Brown, Cindy Castelle, Brian C. Thomas
  • ENGINEERED AND CHIMERIC NUCLEASES
    Publication number: 20250002886
    Abstract: Disclosed herein are engineered nucleases and nuclease systems, including chimeric nucleases and chimeric nuclease systems. Engineered and chimeric nucleases disclosed herein include nucleic acid guided nuclease. Additionally disclosed herein are methods of generating engineered nucleases and methods of using the same.
    Type: Application
    Filed: September 13, 2024
    Publication date: January 2, 2025
    Inventors: Brian C. Thomas, Alan Brooks, Christopher Brown, Cristina Noel Butterfield, Daniela S.A. Goltsman, Jyun-Liang Lin, Isabel Nocedal, Morayma Temoche-Diaz
  • BASE EDITING ENZYMES
    Publication number: 20240309404
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: May 2, 2024
    Publication date: September 19, 2024
    Inventors: Brian C. THOMAS, Jyun-Liang LIN, Alan BROOKS, Cristina BUTTERFIELD, Christopher BROWN, Cindy CASTELLE, Morayma TEMOCHE-DIAZ, Benjamin FREEMAN, Christine ROMANO, Rebecca LAMOTHE
  • ENGINEERED AND CHIMERIC NUCLEASES
    Publication number: 20230416710
    Abstract: Disclosed herein are engineered nucleases and nuclease systems, including chimeric nucleases and chimeric nuclease systems. Engineered and chimeric nucleases disclosed herein include nucleic acid guided nuclease. Additionally disclosed herein are methods of generating engineered nucleases and methods of using the same.
    Type: Application
    Filed: November 17, 2022
    Publication date: December 28, 2023
    Inventors: Brian C. THOMAS, Christopher BROWN, Cristina BUTTERFIELD, Jyun-Liang LIN, Alan BROOKS, Morayma M. TEMOCHE-DIAZ, Greg COST, Rebecca LAMOTHE
  • BASE EDITING ENZYMES
    Publication number: 20230374482
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: May 31, 2023
    Publication date: November 23, 2023
    Inventors: Brian C. THOMAS, Alan BROOKS, Cristina BUTTERFIELD, Christopher BROWN, Cindy CASTELLE, Jyun-Liang LIN
  • BASE EDITING ENZYMES
    Publication number: 20230348877
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: March 8, 2023
    Publication date: November 2, 2023
    Inventors: Jyun-Liang LIN, Alan BROOKS, Cristina BUTTERFIELD, Christopher BROWN, Cindy CASTELLE, Brian C. Thomas
  • BASE EDITING ENZYMES
    Publication number: 20230348876
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: March 7, 2023
    Publication date: November 2, 2023
    Inventors: Jyun-Liang LIN, Alan BROOKS, Cristina BUTTERFIELD, Christopher BROWN, Cindy CASTELLE, Brian C. Thomas
  • BASE EDITING ENZYMES
    Publication number: 20220364067
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: June 15, 2022
    Publication date: November 17, 2022
    Inventors: Jyun-Liang LIN, Alan BROOKS, Cristina BUTTERFIELD, Christopher BROWN, Cindy CASTELLE