Patents by Inventor K. Aoki

K. Aoki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of the Neurotoxic Component of a Botulinum Toxin
    Publication number: 20080096822
    Abstract: A method and composition for treating a patient suffering from a disease, disorder or condition and associated pain include the administration to the patient of a therapeutically effective amount of a neurotoxin selected from a group consisting of Botulinum toxin types A, B, C, D, E, F and G.
    Type: Application
    Filed: December 18, 2007
    Publication date: April 24, 2008
    Applicant: ALLERGAN, INC
    Inventors: K. Aoki, Michael Grayston, Steven Carlson, Judith Leon
  • NEUROTOXIC COMPONENT OF A BOTULINUM TOXIN
    Publication number: 20080003318
    Abstract: A method and composition for treating a patient suffering from a disease, disorder or condition and associated pain include the administration to the patient of a therapeutically effective amount of a neurotoxin selected from a group consisting of Botulinum toxin types A, B, C, D, E, F and G.
    Type: Application
    Filed: February 15, 2007
    Publication date: January 3, 2008
    Applicant: ALLERGAN, INC.
    Inventors: K. Aoki, Michael Grayston, Steven Carlson, Judith Leon
  • METHOD FOR TREATING SMOOTH MUSCLE DISORDERS WITH A NEUROTOXIC COMPONENT OF A BOTULINUM TOXIN
    Publication number: 20080004219
    Abstract: A method and composition for treating a patient suffering from a disease, disorder or condition and associated pain include the administration to the patient of a therapeutically effective amount of a neurotoxin selected from a group consisting of Botulinum toxin types A, B, C, D, E, F and G.
    Type: Application
    Filed: February 15, 2007
    Publication date: January 3, 2008
    Applicant: ALLERGAN, INC.
    Inventors: K. Aoki, Michael Grayston, Steven Carlson, Judith Leon
  • USE OF THE NEUROTOXIC COMPONENT OF A BOTULINUM TOXIN FOR THE TREATMENT OF PAIN ASSOCIATED WITH MUSCLE ACTIVITY OR CONTRACTURE
    Publication number: 20070202129
    Abstract: A method and composition for treating a patient suffering from a disease, disorder or condition and associated pain include the administration to the patient of a therapeutically effective amount of a neurotoxin selected from a group consisting of Botulinum toxin types A, B, C, D, E, F and G.
    Type: Application
    Filed: April 26, 2007
    Publication date: August 30, 2007
    Applicant: ALLERGAN, INC.
    Inventors: K. Aoki, Michael Grayston, Steven Carlson, Judith Leon
  • Post-translational modifications and Clostridial neurotoxins
    Publication number: 20060258843
    Abstract: The present invention discloses modified neurotoxins with altered biological persistence. In one embodiment, the modified neurotoxins are derived from Clostridial botulinum toxins. Such modified neurotoxins may be employed in treating various conditions, including but not limited to muscular disorders, hyperhidrosis, and pain.
    Type: Application
    Filed: May 31, 2005
    Publication date: November 16, 2006
    Inventors: Lance Steward, Ester Fernandez-Salas, Athena Spanoyannis, K. Aoki, Wei-Jen Lin
  • Methods for treating myofascial pain
    Publication number: 20060210589
    Abstract: A method and composition for treating a patient suffering from a disease, disorder or condition and associated pain include the administration to the patient of a therapeutically effective amount of a neurotoxin selected from a group consisting of Botulinum toxin types A, B, C, D, E, F and G.
    Type: Application
    Filed: April 13, 2006
    Publication date: September 21, 2006
    Inventors: K. Aoki, Michael Grayston, Steven Carlson, Judith Leon
  • Chimera botulinum toxin type E
    Publication number: 20060039929
    Abstract: The present invention relates to a toxin comprising a modified light chain of a botulinum toxin type E, wherein the modified light chain comprises amino acid sequence PFVNKQFN (SEQ ID NO: 144) at the N-terminus, and amino acid sequence xExxxLL (SEQ ID NO: 112) at the C-terminus, wherein x is any amino acid.
    Type: Application
    Filed: January 14, 2005
    Publication date: February 23, 2006
    Inventors: Ester Fernandez-Salas, Lance Steward, Todd Herrington, K. Aoki
  • Methods for treating pain associated with arthritis
    Publication number: 20050266029
    Abstract: A method and composition for treating a patient suffering from a disease, disorder or condition and associated pain include the administration to the patient of a therapeutically effective amount of a neurotoxin selected from a group consisting of Botulinum toxin types A, B, C, D, E, F and G.
    Type: Application
    Filed: June 22, 2005
    Publication date: December 1, 2005
    Applicant: ALLERGAN, INC.
    Inventors: K. Aoki, Michael Grayston, Steven Carlson, Judith Leon
  • Therapeutic use of botulinum toxins types A and B
    Publication number: 20050129716
    Abstract: A method of treating a patient suffering from a disease, disorder or condition includes the administration to the patient of a therapeutically effective amount of botulinum toxin of a selected serotype until the patient experiences loss of clinical response to the administered botulinum toxin and thereafter administering to the patient a therapeutically effective amount of another botulinum toxin of a different serotype.
    Type: Application
    Filed: January 5, 2004
    Publication date: June 16, 2005
    Inventors: K. Aoki, Michael Grayston, Steven Carlson, Judith Leon
  • Methods for treating various disorders with a neurotoxic component of a botulinum toxin
    Publication number: 20050084504
    Abstract: A method and composition for treating a patient suffering from a disease, disorder or condition and associated pain include the administration to the patient of a therapeutically effective amount of a neurotoxin selected from a group consisting of Botulinum toxin types A, B, C, D, E, F and G.
    Type: Application
    Filed: September 2, 2004
    Publication date: April 21, 2005
    Applicant: ALLERGAN, INC.
    Inventors: K. Aoki, Michael Grayston, Steven Carlson